ie Pocket 



ARMACY 



by John Aulde 



H 




Class J^_5j_i._ 



Book. 







OopyrightN - 



COFYRIGHT DEPOSIT. 



THE POCKET PHARMACY 

WITH THERAPEUTIC INDEX 



A RESUME OF THE CLINICAL APPLICATIONS OF 

REMEDIES ADAPTED TO THE POCKET-CASE, 

FOR THE TREATMENT OF EMERGENCIES AND ACUTE DISEASES 



BY 

JOHN AULDE, M. D. 



o 



SECOND EDITION 



•> r o o ■ o „ 



NEW YORK 
D. APPLETON AND COMPANY 

1901 



^ 



y* 



+HE L5BRARY Oh 
CONGRESS, 

Two Cop»E3 Received 

NOV, 16 1901 

Copyright entry 
CLASS Co XXc J 

I copy a 



Copyright, 1892, 1901, 
By D. APPLETON AND COMPANY. 



All rights reserved. 



c$y 



•: • • •• 



•• •• 



PREFACE TO SECOND EDITION. 



In preparing the copy for a new edition some 
minor corrections have been made and a new 
section added, on Nuclein, a remedy which will 
be found serviceable to the physician in general 
practice in a wide range of cases. No changes 
have been made in the original teachings, since 
clinical experience fully confirms their practical 
value. Indeed, the entire work is based upon 
bedside observation, although, unfortunately, 
through a slight ambiguity in the text, the in- 
ference was drawn that the recommendations 
were based entirely on speculative investigations. 

In most instances reviewers dealt kindly with 
the book, due appreciation for which is hereby 
acknowledged, but some of the criticisms would 
have been amusing had they not been ridiculous. 
One writer said there were too many indications 
for well-known remedies, although reference to 
Bartholow, Brunton, and Ringer will show others 

3 



4 THE POCKET PHARMACY. 

not included in these notes. Several regarded 
the doses advised as too small, while a limited 
number condemned them as too large. The truth 
is that the doses — i. e., tablets — were adapted to 
meet the probable demands of the physician upon 
his pocket pharmacy in the treatment of emergen- 
cies and acute diseases at all seasons of the year 
and for all classes of patients. Where one tablet 
is regarded as too small, two or more can be ad- 
ministered, or the intervals shortened, and the 
tablets carrying too large a dose can readily be 
dissolved in water and given in the form of a 
solution. 

To the general practitioner of long experience 
the recommendations will be accepted as good 
suggestions, but judging from the many compli- 
mentary letters sent me, I am convinced that the 
little volume has been found to possess intrinsic 
clinical merits of utility, and, in addition, a special 
value for its influence in developing the lines of a 
modern therapy, notably with reference to the 
restoration of cell function as a factor in scientific 
medicine. 

Another criticism related to the uncertainty 
of tablet triturates, but this will scarcely hold now 
that tablets are almost universally employed and 
opposition to their use has subsided. Hence, the 



PREFACE TO SECOND EDITION. 5 

manufacturing chemists of the country are mak- 
ing an effort to extend their lines in this direction, 
by offering to supply physicians with a complete 
outfit. This plan, however, is strikingly systema- 
tized with a view to the introduction of high- 
priced remedies and special combinations, in order 
to secure profits not possible in handling the inex- 
pensive products here advocated. 

The author begs here to acknowledge many 
evidences of appreciation shown by his medical 
confreres, and to assure them of his continued 
interest in the modern trend of scientific medi- 
cine; and, believing that the art medendi can be 
still farther advanced, his present intention is to 
devote several years to study and physiological 
research. 

Edgewood Farm, Kennett Square, Pa. ? 
January, igoi. 



CONTENTS. 



PAGE 

Preface 3 

Introduction 7 

Explanatory note . 13 

acetanilide compound 1 7 

Aconite 24 

Alterative pill 33 

Arsenic sulphide 36 

Atropine sulphate 40 

Bryonia alba 52 

Calcium sulphide 58 

Calcium sulphide compound 67 

Calomel 68 

Camphor ..' 71 

Cannabis indica 75 

Copper arsenite 81 

Gelsemium 98 

Ipecac 106 

Iron arseniate no 

Mercury biniodide 121 

Morphine hydrochlorate 137 

Morphine hydrochlorate and tartar emetic . . . 143 
Quinine hydrochlorate . . . . . . . 146 

Rhus toxicodendron 161 

Strophanthus 167 

Strychnine arseniate 169 

Trinitrin 180 

Zinc sulpho-carbolate 184 

nuclein solution 185 

Therapeutic index 203 

6 



INTRODUCTION. 

In the preparation of the following pages it has 
been found expedient to include references and indica- 
tions for the employment of other remedies besides 
those mentioned in the list of contents. This has been 
done more with a view to guide the recent graduate 
than in the expectation that the small brochure would 
in any event supplant the excellent works on practice 
and therapeutics now in the market. 

For the purpose of bringing before the reader the 
general plan and scope of the work, a brief synopsis 
of the objects sought for in its preparation will not be 
inappropriate. No excuse is necessary for offering to 
the medical profession at this time a fragmentary work 
of this character, since it is well known that a revolu- 
tion is taking place in our methods of practice, due in 
part to the uniform advance of the science, but more 
especially to the revelations of the microscope and 
the study of bacteriology. Notwithstanding the fact 
that too much dependence has been placed upon the 
deductions from laboratory investigations, there is rea- 
son to believe that eventually we shall be better pre- 
pared to interpret the results thus obtained, and turn 
them to therapeutic account in various ways which at 
present we are unable to comprehend. Physiological 
investigation and clinical experience, however, must 



8 THE POCKET PHARMACY. 

go hand in hand, else the superstructure will be frail 
indeed. Clinical experience is the crucial test ; physi- 
ological and chemical postulates, however attractive, 
are entitled to become a part of the medical edifice 
only after their true value has been estimated by this 
searching inquiry. 

Aside from surgical operations and wounds requir- 
ing surgical attendance, nearly all diseased conditions 
may properly be regarded as the result of disordered 
function, the disorder beginning originally in the cell. 
Unfortunately, we are not at present able to recognize 
positively many diseases in the formative period ; 
hence, when frankly declared, the system is surcharged 
with effete material, causing a derangement of function, 
masking the abnormal conditions with which we have 
to contend, and it is not saying too much that great 
harm may follow the indiscriminate employment of 
large doses of medicine. 

Medicine should be administered on the same gen- 
eral plan which governs the use of electricity ; that is, 
by applying it to the part affected. In the treatment 
of lumbago by means of the faradaic current, we apply 
the electrodes to the muscles involved, because gen- 
eral faradization would be of comparatively little value. 
While it would be out of place here to enter into a 
discussion of the physiological questions connected 
with the employment of electricity for this special pur- 
pose, it will serve to illustrate certain principles which 
should be observed in the administration of medicines. 
A quarter of a century ago, and even during later 
years, medicaments have been employed with a view 
to cause a profound effect upon the system without 
any special regard for the peculiar character of the 
disorder present. Thus, mercury for syphilis was given 



INTRODUCTION. g 

to produce salivation ; purgatives were employed with 
the expectation that free catharsis would preclude the 
necessity for bleeding. Astringents were employed 
with the firm belief that they possessed some occult 
power which would correct all the harm following the 
exhibition of purgatives, and rational medicine as late 
as a decade ago presented the sad spectacle of a medley 
of contradictions. To the thoughtful student it was 
decidedly irrational. 

We are now, however, approaching the dawn of a 
brighter day, as we are learning to set aside the gross 
manifestations of disease in order that we may study 
more closely the derangement of cell-function, upon 
which they depend. Having acquired this knowledge 
by studying the pathological changes occurring in dis- 
ease, we endeavor to discover, if possible, remedies 
which, by their known physiological actions, would be 
best calculated to arrest or counteract the changes 
occurring in disease. This naturally leads us to study 
the effect of medication upon the diseased cell, which, 
being interpreted, means clinical observation, the basis 
of all successful therapy. So thoroughly convinced 
am I of this being the true method of studying the 
virtues of therapeutic agents that I have rather hesi- 
tatingly called it "cellular therapy." 

If this doctrine be true, and the recommendations 
in the succeeding pages, if faithfully carried out, may 
be verified by any physician, then it follows that small 
doses are to be preferred — in fact, they are a necessity. 
The rule that all functions are impaired by over-stimu- 
lation applies with even greater force to cell-function, 
upon which the integrity of vital organs depends. The 
proposition is axiomatic, and requires no attempt in 
the way of demonstration Thousands of physicians 



IO THE POCKET PHARMACY. 

can testify to the therapeutic value of properly selected 
remedies, although they may have been unable hitherto 
to give a satisfactory explanation of the same. In 
the light furnished by the doctrine of cellular therapy, 
the solution is easy; th'e opportunity to demonstrate 
its practical utility is within the reach of every phy- 
sician who will study the subject in an unprejudiced 
manner. 

There are several factors entering into the question 
of the advantages of administering small doses of 
medicine which may profitably be passed in review. 
Incidentally, this subject has received attention under 
the different medicaments selected, the object being to 
elucidate more clearly the general principles involved 
and underlying the treatment of disease according to 
the method advocated. These factors may be grouped 
as follows: 

i. Medicines, for the most part, are poisons, and, as 
a consequence, extreme caution is necessary in their 
employment in order to avoid injuring the delicate 
structures or deranging functions. While it is true 
that they do contain the elementary principles, their 
combination is such that they are well calculated to 
produce harmful results unless properly guarded by 
the skillful and conscientious physician. Strophanthus, 
well known as a deadly arrow-poison in Central Africa, 
is probably one of our most active and reliable car- 
diac medicaments. Arsenite of copper, used in the 
form of Paris-green, is one of the drugs used by those 
of suicidal intent, and generally succeeds in producing 
death, preceded by violent vomiting and purging, but 
it is a very useful stomachic and intestinal remedy. 
Aconite is another poison which has served the medi- 
cal profession well, but used by the laity without a 



INTRODUCTION. II 

proper knowledge of its properties, it has undoubtedly 
done a great deal of harm. 

2. Medicines act in very many cases through the 
nervous system, being distributed by the blood, al- 
though some of them remain in the tissues, by which 
means the nerves are constantly brought into contact 
with the drug, either in its original form or under 
some modified form brought about by the action of 
the economy. There is a belief prevalent that all 
poisons, unless promptly eliminated, are carried direct 
to the liver, hence this organ is liable to suffer during 
continued medication when proper care is not taken to 
avoid accumulation. 

3. Medicines have in some instances what is termed 
a specific action. Thus, quinine is given for malaria, 
mercury for syphilis, aconite for fever, rhus toxico- 
dendron and salicylates for rheumatic affections, and 
bryonia for inflammatory conditions affecting serous 
membranes. 

4. Medicines are said to be " alterative " when cer- 
tain effects follow their administration, which can not 
be definitely explained upon a physiological basis. 
Arsenic has always been regarded as a powerful alter- 
ative, and it is only within recent years that we have 
been able to form any definite conceptions of the role 
it plays in the economy. By studying its effects upon 
the modifications of cell activity in diseased conditions, 
much useful information will be gained concerning its 
true value ; it will then be employed with more pre- 
cision and with better results from a therapeutic stand- 
point. 

The recommendations here put forward are in many 
instances based upon speculative investigations ; rea- 
soning from analogy has enabled me to extend the 



I2 THE POCKET PHARMACY. 

employment of a number of remedies where thera- 
peutic virtues have been demonstrated by the con- 
vincing evidence furnished by clinical experiment. 

The original plan contemplated a brief preliminary 
note attached to each of the selected remedies, intended 
to cover their physiological actions, but the notes ac- 
cumulated so rapidly that at the last moment this feat- 
ure was abandoned. Owing to lack of space, a large 
amount of valuable material has been discarded, so 
that " unsupported statements " must be tested by 
members of the profession who favor reform by mak- 
ing an advance air along the line. 



EXPLANATORY NOTE. 



THE POCKET PHARMACY. 



CONTENTS. 



Acetanilide compound : 

5 Acetanilide, 70 parts. 
Caffeine, 10 parts. 
Sodium bicarb. (C. P.), 20 
parts. 

Aconite, tincture, ^l ss. 

Alterative pill : 

5 Pulv. opii, 

Pulv. ipecac, aa gr. 1 / 8 . 

Mass. hydrarg., gr. ss. 
M. et ft. pil. no. j. 

Arsenic sulphide, gr. x / IOO , 

Atropine sulphate, gr. z / soo . 

Bryonia, tincture, Til ss. 

Calcium sulphide, gr. x / 10 . 

Calcium sulphide com- 
pound : 

5 Morphinse hydrochloras, 
Pilocarpine hydrochloras, 

aa gr. V200. 
Calcii sulphidi, gr. ^40 . 

M. et ft. pil. no, j. 

Calomel, gr.%. 

Camphor, saturated tinct- 
ure, tt], y 4 . 



Cannabis indica, ext., gr. 

/ao- 

Copper arsenite, gr. x / ioo . 
Gelsemium, fl. ex., m ss. 
Ipecac, gr. y 4 . 
Iron arseniate, gr. x / 25 . 
Mercury biniodide, gr. x / ioo . 
Morphine hydrochlorate, 

gr. 1 /*. 
Morphine hydrochlorate 

and tartar emetic, aa 

Nuclein solution, iil 48 / I5 o. 
Quinine hydrochlorate, 

gr. y 4 . ^ 

Rhus toxicodendron, tinct- 
ure, TTl ss. 

Strophanthus, tinct., TTl ij. 
Strychnine arseniate, gr. 

/roo • 

Trinitrin, gr.y 2S0 . 

Zinc sulphocarbolate, 
gr. ss. 



14 



THE POCKET PHARMACY. 



The pocket-case containing the foregoing medica- 
ments is of the following dimensions : 4 X 6 3 / 4 X 3 / 4 
inches, contains twenty-four phials, 13 X 43 mm., and 
is adapted to the pocket of an ordinary coat. The 
medicines have been selected with a view to meet emer- 
gencies, although it will be found useful by general 
practitioners in the treatment of diseases of children, 
and is calculated to carry sufficient material for the 
ordinary wants of a physician who is not engaged in 
special lines of practice. No doubt many have felt 
the need of such a convenience, and lately quite a 
number of practitioners have been supplying them- 
selves with such an outfit, but in making the attempt 
great difficulty has been experienced, owing to the in- 
ability to obtain medicines in such form that they could 
be conveniently used at the bedside. This difficulty, 
however, no longer exists, as tablet triturates and 
small pills or granules can be obtained through manu- 
facturing pharmacists at very reasonable prices, per- 
fectly reliable. If properly kept — free from light, heat, 
and moisture — these pellets will not deteriorate with 
age, although it is advisable from time to time to test 
their solubility. Those who prefer to use liquids can 
do so, but they are far less convenient than the pills or 
tablets. 

In giving directions for use, where it is advised 
that certain medicaments be given together or in com- 
bination, it means simply that they are to be given at 
the same time, although they are not mixed before ad- 
ministration. Occasionally it will be found best to 
give medicines to children in liquid form, in which 
case the pills can be dissolved separately in water; 
they are then usually taken in teaspoonful doses at the 
intervals suggested. The doses advised are those gen- 



EXPLANATORY NOTE. 1 5 

erally indicated ; the same is true of the periods at 
which the medicine should be taken, but, of course, 
there will be special occasions when these directions 
must be varied. That is a matter wholly within the 
province of the physician, but the suggestion is made 
that these directions be adopted in the beginning ; they 
ought to be continued until there is substantial reason 
for making a change. Physicians who adopt this plan 
for the first time will be surprised at the prompt effects 
secured from medicine, but they will be more aston- 
ished at the number of ailments which can be met by 
this small number of drugs, all because of the more 
thorough acquaintance with their therapeutic proper- 
ties. 

But little space could be spared for directions in 
regard to diet and hygiene, but a few hints are given 
in different sections. 

Directions have been given for " solutions " of ar- 
senite of copper for local use. A small bottle of tab- 
lets, each containing one grain of the crude drug, 
should be kept in stock ; one of these tablets is added 
to four ounces of boiled water, and, in order to effect a 
perfectly clear solution, diluted hydrochloric acid is 
added drop by drop — the mixture being frequently 
shaken, until all of the coloring matter disappears. 
This is substantially a solution of the chlor-arsenite of 
copper, and will be found a remedy of great utility. 

In giving directions for the employment of medica- 
ments directed to the condition of the alimentary canal, 
I have frequently suggested the employment of a " sa- 
line." I have had excellent results from the use in 
this manner of magnesium sulphate deprived of its 
water of crystallization ; after drying, it appears in the 
form of a fine white powder, and with a few drops of 



j6 THE POCKET PHARMACYo 

lemon-juice and a little water children will take it 
readily. Care must be exercised, however, that too 
much water is not allowed, which would increase the 
activity of'the kidneys and produce no effect upon the 
bowels. Taken in the early morning, a teaspoonful of 
the dried salts in less than a third of a goblet of water 
will usually produce one or more free movements of 
the bowels ; but the dose must not be repeated too 
frequently, else a bad habit of the intestinal tract will 
be developed. 

The " Therapeutic Index," or " Index of Diseases," 
includes over one thousand references, and is arranged 
alphabetically throughout for convenience. Under the 
various medicaments, which are themselves in alpha- 
betical order, the diseases follow r in like manner ; and 
in referring to the different remedies for any particu- 
lar disease, the latter will be readily found by running 
the eye over the list, which has been printed in bold- 
faced type. 

The medicaments best suited to this plan of medi- 
cation include tablet triturates (half-grain size), com- 
pressed tablets, and small pills or granules, each of 
which contains the exact amount of the drug. The 
fact that solutions are frequently recommended will 
enable the physician to determine from time to time 
their solubility. 

The pocket-case is offered to the medical profession 
with the utmost confidence that the contents will be 
found, upon judicious use, to produce the effects prom- 
ised ; but these medicaments must be given with proper 
regard for the diseased conditions present, and not 
used hap-hazard. 



THE POCKET PHARMACY. 



ACETANILIDE COMPOUND. 

Formula : ]J Acetanilide 70 parts ; 

Caffeine 10 parts ; 

Sodium bicarb. (C. P.) . . 20 parts. 

Each tablet, pill, or granule contains a total of half 
a grain, being approximately one third of a grain of 
acetanilide and one twentieth of a grain of the alkaloid 
caffeine. For convenience in administration in special 
cases, where larger doses are required, tablets each 
containing a total of two grains will be found de- 
sirable. The small dose is best adapted to children. 

Alcoholism. — May be used as a temporary ex- 
pedient in place of the bromides, chloral, or chlorala- 
mid in delirium tremens. It will be well in these cases 
to give in combination with the drug strychnine ar- 
seniate, cannabis indica, or capsicum, according to the 
special indications. 

Angina Pectoris. — It may be used cautiously in 
this disease to relieve the pain. One or two pills can 
be given every five minutes until six pills are taken, 
when an* interval should be allowed before again ex- 
hibiting the medicine. 

Catarrh, Acute Nasal. — In these cases, as seen 
in adults, a pill should be given every ten minutes for 
2 



1 8 THE POCKET PHARMACY, 

an hour, then at less frequent intervals, to relieve 
headache, congestion, or neuralgic pains. 

Convulsions. — Most efficacious for the relief of 
local irritation acting as the exciting cause. A dose is 
given every ten minutes for an hour, other treatment 
being directed to the cause. 

Dentition. — This remedy promises the best results 
in overcoming the irritation due to teething. A pill 
may be given every two hours until several doses have 
been taken. In case of convulsions, several may be 
given during the first hour, when a hot bath or wet 
pack is indicated. The condition of the digestive ap- 
paratus should then receive attention, teething troubles 
being frequently due to a lack of bone-making ma- 
terial. Phosphoric acid would be a suitable remedy. 

Diphtheria. — May be used cautiously to relieve 
hyperpyrexia; whether in frequent small doses or a 
single large dose, must be determined by the individual 
susceptibility of the patient. A dose may be given 
every ten minutes for an hour to a child five years of 
age, the effect studied, and the temperature taken an 
hour after the administration of the last dose. In case 
large doses are required or deemed advisable, the 
remedy should be guarded by strophanthus or strych- 
nine arseniate. Collapse will require the rectal ad- 
ministration of oxygen gas or the employment of a 
solution of hydrogen peroxide by enema. 

Enteritis. — May be used in place of anodynes and 
hypnotics in persons who are spare — not anaemic — but 
not so advantageously in sthenic cases. A dose is 
given every ten minutes for an hour, then less fre- 
quently. 

Fever. — Will be found useful in the treatment of 
nearly all cases in which hyperpyrexia forms an ele- 



ACETANILIDE COMPOUND. ICJ 

ment of danger, but must be given with caution to 
"flabby" patients, owing to its unfavorable influence 
upon the cardiac muscle and contained ganglia. An 
adult can take a pill every half-hour for several hours 
as a preliminary to the administration of larger doses, 
but the temperature and condition of the circulation 
must be carefully watched. 

Gastralgia. — Affords in many cases instant relief 
in gastralgia, gastric ulcer, and gastritis, and along 
with antiseptics and suitable diet great improvement 
will follow. It is especially useful when the gastritis 
is associated with migraine and the attacks paroxys- 
mal. As these attacks often depend upon a sluggish 
condition of the liver, it is well to add mercury bini- 
odide to the treatment. 

Glandular Enlargement. — Maybe used to allay 
pain when the tumors occur about the neck. A pill 
can be given every hour or two. 

Gout. — It promises to be of service in allaying the 
pain when the condition of the heart will admit of its 
employment. One or two pills are given every hour 
for several hours, until dosage and tolerance are estab- 
lished. 

Headache. — It is useful in nearly all forms of 
headache as a palliative. A pill is taken every ten 
minutes for an hour, or, in case the condition of the 
patient will warrant, several pills may be given at once. 

Heart, Hypertrophied. — Aids materially in regu- 
lating arterial tension and relieving pain, if used in 
small doses. A dose is given every hour or two. 

Hectic. — Produces a feeling of comfort, but is only 
palliative. It should be given preferably in the fore- 
noon, when the temperature is rising ; a dose every half- 
hour for several hours. 



20 THE POCKET PHARMACY. 

Hematuria. — Useful to check pain and create a 
feeling of comparative comfort ; a dose every half-hour 
until relief is afforded. 

Haemoptysis. — Produces an effect upon the circu- 
lation which adapts the system to other treatment, and 
in addition it will relieve the pain. A single dose of 
three grains may be given, or several smaller doses at 
intervals of ten minutes. 

Haemorrhage, Intestinal. — May be permitted to 
take the place of morphine in suitable cases, but the 
condition of the circulation and the temperature must 
be carefully studied in order to avoid unfavorable 
symptoms. 

Hepatitis. — Is useful to allay pain and subdue high 
temperature in suitable cases. A dose is given every 
ten minutes for an hour, and this is repeated in the 
course of a few hours. 

Hysteria. — May have a favorable effect in allaying 
the excitement ; a dose is given every half-hour for 
several hours. 

Influenza. — Used as an analgesic to relieve head- 
ache and neuralgia, and as an antipyretic in the early 
stages to reduce the temperature. It is advisable in 
these cases to combine it with quinine ; two grains of 
each given every three hours will relieve headache 
and other pains, stimulate the cutaneous system, re- 
duce fever, promote sleep, and effect a marked change 
for the better in twenty-four hours in most threaten- 
ing cases. 

Insomnia. — Useful when due to nervous depres- 
sion, chronic alcoholism, or reflex irritation ; a pill is 
given every ten minutes for an hour. 

Intermittent. — To control neuralgia — " brow- 
ague," often a concomitant of the disease — a dose is 



ACETANILIDE COMPOUND. 21 

given every ten minutes for an hour, the patient being 
advised to avoid exposure to the sun and the mias- 
matic influences of the early mornings and evenings. 

Laryngismus Stridulus. — Ought to be of value 
here as an antispasmodic. A child five years of age 
suffering from this disease can take a pill every ten 
minutes for an hour. 

Locomotor Ataxia. — Relieves the pain and pro- 
motes sleep without in any way deranging the digest- 
ive apparatus. In case a pill every hour during the 
day is not sufficient, or is too troublesome, a tablet 
containing two grains taken three or four times a 
day will prove acceptable. 

Lumbago. — To provide quick relief when there is 
great pain. A pill can be given every ten minutes for 
an hour, or, in suitable cases, three to five grains can 
be administered at once. 

Mania. — May prove of temporary benefit, along 
with cannabis indica ; a dose of each may be given 
every ten minutes for an hour, then at less frequent 
intervals during the day. 

Measles. — A very useful remedy in the early stages 
with high fever and excitement. 

Meningitis, Cerebral. — Useful to allay the pain 
and quiet the nervous system. A dose is given every 
half-hour for several hours, and the effect watched. 

Nervousness. — A dose is given every ten minutes 
for an hour, just previous to retiring, to allay excite- 
ment through its benumbing influence upon the sensory 
nerves. 

Neuralgia. — Almost uniformly affords relief, but 
is not curative in the true sense of the term. A pill 
may be taken every ten minutes for an hour, and re- 
peated in the course of three or four hours. In suit- 



2 2 THE POCKET PHARMACY. 

able cases a tablet containing two grains may be given 
at once, and repeated hourly until several doses are 
taken, when treatment should be directed to removal 
of the cause. 

Parotiditis. — May be used to allay pain ; a dose 
every hour will not interfere with other treatment. 

Pericarditis. — May be employed to allay pain, but 
too much dependence must not be placed upon it. 

Peritonitis. — Should be used cautiously to allay 
pain and reduce temperature, but the effect upon the 
circulation must be noted in case considerable dosage 
is long continued. 

Phthisis. — Is useful to reduce the fever, and is at 
the same time a pain-reliever even in small doses. A 
dose is given every half-hour or hour during the fore- 
noon. 

Pleurisy. — Gives prompt relief from pain, but does 
not seem to arrest the progress of the disease, so that 
other medication must be continued at the same time. 
It may be given with benefit in combination with bry- 
onia. 

Pleurodynia. — Will allay the pain temporarily, 
when treatment can be adopted looking to the removal 
of the cause. 

Pneumonia. — For the cases to which it is adapted 
this combination will prove very valuable as an anal- 
gesic and antipyretic. A dose is given every ten min- 
utes for an hour, then according to the indications. 

Rheumatism, Acute. — May be used for its anti- 
pyretic effect and as an analgesic, but when first ad- 
ministered the tolerance of the patient must be care- 
fully studied. 

Rheumatoid Arthritis. — Useful here simply as 
a pain-reliever, but by promoting sleep the patient is 



ACETANILIDE COMPOUND. 



23 



in a better condition to be benefited by other medi- 
cation. A dose is given every hour or two, or a 
tablet containing two grains is taken three times 
a day. 

Scarlet Fever. — Useful to reduce temperature and 
relieve pain in the early stages of the disease, but care 
must be had to avoid depression as the disease pro- 
gresses. 

Sciatica. — A very useful remedy for the relief of 
pain of all forms. Some preparation of phosphorus 
may be added to the treatment to secure permanent 
relief. 

Seasickness. — Will be of value in relieving head- 
ache for the time being. Creasote in pill form may be 
added to the treatment with benefit. 

Sexual Excitement. — Several doses taken before 
retiring will have a tendency to allay local irritation 
and obtund the sensory nerves ; but hot water should 
be freely used at bed-hour, and, in addition, light 
covering is recommended. 

Spinal Congestion. — Should be used to allay pain 
and lessen tension. In severe cases a single dose of 
three to five grains can be given, and followed by 
smaller doses according to indications. 

Sunstroke. — Of value in thermic fever, but less 
prompt than antipyrine. 

Testicle, Disease of. — Is a suitable remedy for 
the relief of pain ; a dose can be given every ten min- 
utes for an hour, then less frequently. It may be used 
as an anodyne to allay the pain of orchitis and epi- 
didymitis, but caution is necessary when long con- 
tinued. 

Tic-douloureux. — A useful remedy to relieve the 
pain temporarily. A study of the cause will probably 



24 



THE POCKET PHARMACY. 



lead to the employment of medicaments calculated to 
correct the diathesis upon which it depends. 

Toothache. — To subdue the pain of abscess form- 
ing at the root ; and may also be employed to relieve 
toothache occurring from exposure to cold. 

Typhoid Fever. — Of value to relieve pain and as 
an antipyretic, but must be given cautiously to " flab- 
by " patients at any stage of the disease. It is best 
adapted to cases of hyperpyrexia, when two to six 
grains can be given at once in the early portion of the 
day, to be followed later by two-grain doses not oftener 
than two hours, although it should not be continued 
later than six o'clock in the evening. It must be given 
with discrimination after the disease has been in prog- 
ress for a period of two weeks. The neuralgic pains 
sometimes ushering in the disease may be promptly 
subdued by this combination. 



ACONITE. 

Each tablet, pill, or granule contains one half minim 
of the tincture, prepared from the root which has been 
subjected to assay, and is known to contain a specified 
percentage of alkaloid. 

Amenorrhcea. — It is useful in those cases where 
the menses are suddenly checked by exposure, asso- 
ciated with heightened temperature and rapid pulse ; 
should be combined with gelsemium and followed by 
strychnine arseniate, to overcome the depression suc- 
ceeding an attack. Pulsatilla is also highly recom- 
mended, but there may be indications for bryonia and 
cannabis indica. 

Aneurism. — May be employed in aneurism to slow 



ACONITE. 25 

the circulation, but is less efficient in relieving pain 
than bryonia. Barium chloride and ergot, with a light 
diet (the patient to remain in the recumbent posture), 
are effective measures. 

Angina Pectoris. — Is a useful remedy when there 
is increased cardiac activity, although gelsemium is 
probably preferable as a temporary expedient. Alter- 
ative remedies are especially indicated. 

Aphonia. — Has been recommended in painful con- 
tractions of the throat which sometimes affect singers, 
but can not compare in efficiency with belladonna and 
bryonia. 

Apoplexy. — Is employed to decrease arterial ten- 
sion and lessen the frequency of the pulse, Much 
benefit will be secured by the addition of gelsemium 
and small doses of strychnine arseniate. 

Asthma. — Is sometimes useful in the asthma ac- 
companying nasal catarrh in children, but copper ar- 
senite in the form of a solution is preferable. 

Bronchitis. — In acute bronchitis a pill is given 
every ten minutes for an hour at the beginning of an 
attack, then at less frequent intervals — the medicine to 
be dissolved in the mouth The recumbent posture is 
believed to favor early recovery. 

Catarrh, Acute Nasal. — Useful at the beginning 
of an attack in both adults and children. For adults 
a dose is given every ten minutes for an hour, then at 
less frequent intervals. 

Cerebral Concussion. — In the treatment of this 
disease aconite is to be combined with gelsemium ; 
both to be given until some of the physiological effects 
are observed, and followed by the exhibition of calcium 
sulphide and bryonia. 

Cerebral Congestion. — To reduce the activity of 



2 6 THE POCKET PHARMACY. 

the circulation and prevent effusion. Bryonia is indi- 
cated at the same time, when pain exists. 

Chordee. — A dose is given every half-hour, begin- 
ning early in the afternoon ; a light covering to be used 
at night, and the parts to be bathed freely with hot 
water before retiring. 

Climacteric Disorders. — Will relieve the head- 
ache, fidgets, and palpitation ; a dose every ten min- 
utes for an hour, then one every hour — the pill to be 
dissolved in the mouth. 

Convulsions. — To lessen arterial tension ; a dose 
every ten minutes, alone or in combination with gel- 
semium. 

Cough. — Valuable in that form known as 4< throat 
cough," along with atropine ; a dose of aconite is dis- 
solved in the mouth every hour. 

Croup. — In the early stages of the catarrhal form 
to subdue inflammation, with atropine to check secre- 
tion and lessen spasm. In addition, it will be found 
beneficial to use a spray of a solution of hydrogen per- 
oxide (Marchand's). A pill is dissolved in the mouth 
every ten minutes for an hour, and a dose of atropine 
is taken at intervals of an hour or two in the same 
manner. Our object in these cases is to prevent the 
formation of membrane, and maintain as far as possible 
antisepsis. Emetics, unless used with great circumspec- 
tion, by causing depression, do more harm than good. 

Cystitis. — Is used to relieve fever in acute cases, 
along with atropine or hyoscyamus, to be followed by 
the administration of quinine. 

Diarrhoea. — To reduce the pulse-rate and temper- 
ature, with bryonia to allay the sharp, lancinating pains. 
A dose of each is given every hour, with copper arsen- 
ite, as indicated. 



ACONITE. 



27 



Dropsy. — It is indicated in that form of dropsy 
occurring in scarlet fever, accompanied by a rise in 
temperature. 

Dysmenorrhea. — Useful in the congestive form, 
or when the menses cease suddenly after exposure to 
cold. A dose every ten minutes for an hour, then at 
less frequent intervals. It may be used in combination 
with gelsemium or cannabis indica to advantage, ac- 
cording to the special indications presenting. 

Endocarditis. — Given in small doses at short in- 
tervals, it will modify favorably the force of the dis- 
ease, if it does not act as a prophylactic. The patient 
should maintain the recumbent posture. 

Enteritis. — Aconite is useful in the acute stage; 
a dose every half-hour until the activity of the circu- 
lation is subdued. 

Epistaxis. — Useful in the treatment of children, to 
reduce the pulse-rate; the patient to maintain the up- 
right posture. 

Erysipelas. — Valuable at the commencement only ; 
when the skin is hot and dry, it should be alternated 
with rhus toxicodendron. Not infrequently the addi- 
tion of gelsemium will more quickly reduce the pulse 
and temperature than aconite alone. 

Fever. — Aconite is a remedy whose value in the 
treatment of fever can not be doubted. Some authors 
would have us believe its application so universal that 
the medicament and thermometer should go hand in 
hand, but there are serious objections to the adoption 
of this as a rule of practice. For the most part, the 
employment of aconite, and other remedies of this class, 
is nothing more than symptomatic treatment. True, 
aconite favors the discharge of heat from the body, 
aids in carrying off effete material through increased 



2 8 THE POCKET PHARMACY. 

urinary secretion and greater activity of the cutaneous 
system, but it does not lessen the heat-production. 
The successful employment of aconite hinges upon the 
physical condition of the patient and the type or char- 
acter of the disease. The reduced pulse which aconite 
produces seems to favor the activity of certain con- 
servative or vegetative processes in nature, which tend 
to reorganize, so to speak, the normal functions. In 
other words, as the circulation approaches the normal, 
a more favorable opportunity presents for cell-activity 
being restored. Hence it is that aconite is said to be 
best adapted to the strong and robust — the sthenic 
cases. If given in the early stage of fever to persons 
who have previously enjoyed fairly good health, this 
remedy will generally produce most remarkable results, 
unless the type or character of the disease be of such 
a nature that arterial sedatives will have no influence 
upon its course. As examples may be cited fulminant 
cases of diphtheria, grave attacks of scarlet or typhoid 
fever, where aconite must be employed with discrimi- 
nation. The remedy should be given in small doses at 
short intervals, in order to keep the blood charged with 
it, while the effect upon the temperature and circulation 
must be frequently noted. 

Aconite in toxic doses is deposited in the tissues ; 
the blood of an animal poisoned by the drug is harm- 
less to another animal. The question, then, for us to 
decide where aconite seems to be clearly indicated is, 
How shall we best secure the effect upon the pulse ? 
In case large doses at long intervals are decided upon, 
we must be prepared to witness untoward effects when 
the tissues become surcharged with the poison ; the 
effect upon cell activity may be the opposite of that 
desired, and as a consequence the large doses decrease 



ACONITE. 



2 9 



temperature only to be followed by a rise. In the ex- 
hibition of the small dose the effect is secured through 
the action of the remedy upon the nerve-cells regulat- 
ing the circulatory apparatus, but no opportunity is 
afforded for cumulative action, as above described ; 
the effect is produced through the blood, rather than 
through the medium of the tissues, and much depres- 
sion to the patient thereby saved. In the exhibition 
of the drug, therefore, these factors must be kept con- 
stantly in view if we desire to obtain therapeutic re- 
sults and avoid the bad effects. 

Gonorrhoea. — Employed in the acute stage, alone 
or with gelsemium, to quiet arterial excitement. A 
dose may be given every hour or half-hour. 

Headache. — Indicated when the face is flushed, 
showing a disturbance of the tension of the capillaries. 
Small doses of aconite at short intervals not only re- 
duce the pulse-rate, but favor the contraction of the 
capillaries. A dose may be given every ten minutes 
for an hour — the pill to be dissolved in the mouth. 

Heart, Hypertrophied. — Should be used cau- 
tiously and in very small doses, especially when there 
is valvular disease. A dose every three or four hours 
dissolved in the mouth. 

Heart, Valvular Disease of the. — Small doses 
can be given, but great caution is necessary ; the 
patient should maintain the recumbent posture. 

Haemoptysis. — Aconite may be used in conjunc- 
tion with ergot hypodermatically to reduce the pulse- 
rate. A dose may be given every five or ten minutes 
for an hour ; the addition of gelsemium will be advis- 
able, unless there be some special contra-indication. 

Hepatitis. — Used to reduce the pulse-rate and 
favor the activity of the skin and kidneys. 



30 



THE POCKET PHARxMACY. 



Inflammation. — Useful in the beginning to reduce 
the pulse-rate and temperature, alone or in combina- 
tion with gelsemium. A dose is given every ten min- 
utes for an hour, then at less frequent intervals. 

Influenza. — Applicable in the early stages, but con- 
tinued too long causes depression. A dose is given 
every ten minutes for an hour, then at less frequent 
intervals for twenty-four or forty-eight hours. 

Insomnia. — Useful when dependent upon derange- 
ment of the capillary circulation ; indicated when the 
skin is dry, with elevated arterial tension. A pill is 
given every ten minutes for an hour. 

Intermittent. — Aconite is used as a preliminary 
treatment to the administration of quinine; it may be 
combined with gelsemium to advantage. A pill of each 
is given every ten minutes for an hour or two, or until 
the skin becomes moist and the arterial tension is 
lowered. 

Laryngitis, Acute. — To reduce the pulse-rate and 
counteract the local congestion. Excellent results fol- 
low its combination with atropine. The preliminary 
treatment should be followed by the use of calcium 
sulphide — a pill every two hours. 

Measles. — It is useful to reduce fever and bronchial 
congestion, alone or with gelsemium; a dose every 
half-hour for a child three years of age during the fore- 
noon, to be followed by quinine. 

Meningitis, Cerebral.— To subdue the activity of 
the circulation ; a dose is given every half-hour for 
several hours. 

Metritis.— In the acute stage, along with a hot 
douche of a solution of hydrogen peroxide, and followed 
by calcium sulphide. 

Nephritis, Acute.— Aconite in the acute nephritis 



ACONITE. 



31 



of scarlet fever is of decided value; it lessens the 
pulse-rate and reduces the temperature. It may be 
given alone or in combination with gelsemium. 

Nervousness. — A few doses of the tincture may 
be given about bed-hour, at intervals of five minutes; 
the addition of gelsemium is indicated when there is 
high arterial tension. 

Neuralgia. — Is adapted to purely symptomatic 
cases, with high arterial tension and increased pulse- 
rate. A pill is dissolved in the mouth every ten min- 
utes for an hour or two. Aconitine, the alkaloid, is 
considered preferable for the treatment of these cases. 

Parotiditis. — Useful in the early stages along with 
dry heat, but no poultice, except perhaps moist clay. 

Pericarditis. — Used to lessen the frequency of the 
cardiac action when the contractions are strong; a 
dose every hour or two. 

Peritonitis. — Indicated in the early stage to sub- 
due the active circulation. The dose must be regu- 
lated according to the effect produced upon the patient 
in connection with the employment of salines. 

Pertussis.— Is indicated when the pulse is rapid, 
although it has less influence for good in this disorder 
than gelsemium. 

Pharyngitis.— Indicated in combination with atro- 
pine when there is a rapid pulse; a dose is given every 
hour, and followed by calcium sulphide. 

Pleurisy. — Useful in the early stage in combination 
with bryonia, to prevent effusion. 

Pneumonia. — Adapted to the early stages of the 
disease when there is rapid pulse-rate and high tem- 
perature, alone or in combination with gelsemium, to 
be followed at the proper time by quinine. 

Puerperal Convulsions.— Small doses should be 



32 



THE POCKET PHARMACY. 



given at short intervals, but it is important that the 
cause should be removed if possible. Anaesthetics or 
venesection may be required, and local antiseptics are 
always in order. 

Puerperal Fever. — Of value only at the begin- 
ning of an attack. The uterus must be thoroughly 
cleansed, the bowels relieved by salines, and sodium 
salicylate, or quinine given in substantial doses. 

Puerperal Peritonitis. — The use of aconite would 
be the same substantially as recommended for the re- 
lief of puerperal fever, puerperal peritonitis being fre- 
quently but a later stage of the disease. The plan to 
be pursued is practically the same in both cases. 

Rheumatism, Acute. — Is generally employed in 
the early stage, but lately only as a preliminary to the 
use of sodium salicylate or salol. 

Scarlet Fever. — A remedy of great usefulness in 
the early stages to reduce fever and pulse-rate, but 
given too long or in too large doses it has'a bad effect 
upon the heart. 

Testicle, Diseases of the. — Is useful only in the 
early stages of inflammatory action, alone or with 
Pulsatilla, to reduce fever and allay pain. A well- 
fitting suspensory bandage is applied at once, and 
must be worn constantly in order to lessen the force 
of the disease in orchitis and epididymitis. 

Tic-douloureux. — The alkaloid aconitine has been 
highly recommended for the relief of this disorder ; but 
where this is not procurable, a dose of the tincture 
may be given every ten or fifteen minutes, in combina- 
tion with cannabis indica, rhus toxicodendron, mercury 
biniodide, arseniate of iron, or strychnine arseniate, 
according to the indications. 

Tonsillitis. — Always indicated in sore throat, alone 



ACONITE. 



33 



or in combination with atropine, to allay pain and re- 
duce temperature and pulse-rate. Local measures will 
include the use of a solution of hydrogen peroxide, 
together with solutions of an antiseptic character, such 
as copper arsenite or mercury biniodide. 

Trismus. — Will be of some benefit as a preliminary 
treatment, although it is not curative. 

Typhoid Fever. — Should be exhibited only in the 
beginning of the disease, before the true character of 
the malady has been declared. 

Typhus. — Useful only in the early stage, to reduce 
the pulse-rate ; continued longer, it is liable to have a 
depressant effect upon the heart. 



ALTERATIVE PILL. 



[ aa gr. % ; 

2. , ; 



Formula : ]J, Pulvis opii, 

Pulvis ipecac, 

Massae hydrargyri gr. ss. 

Misce et fiat tab. trit. vel pilula no. j. 
Biliousness. — In biliousness with abdominal pain, 
headache, nausea, heavy breath, and constipation, this 
combination answers an admirable purpose. The blue 
mass in small doses, in combination with ipecac, pro- 
duces a favorable action upon the liver and alimentary 
tract and upon the skin, while it contains just sufficient 
opium to allay pain without in any way interfering 
with the secretions. Remarkable effects follow its ju- 
dicious employment. The class of cases to which it is 
adapted might be specified as " bilious " ; there is for 
the most part a regular production (secretion) of bile, 
but after a time, during which elimination is arrested, 
when secretion stops and constipation prevents elimi- 



34 



THE POCKET PHARMACY. 



nation. Usually a pill is given every hour for six or 
eight hours, but when the patient is seen late in the 
day two pills can be given every hour, in which case it 
will be necessary to administer a saline on the follow- 
ing morning. When it is desired to produce a pro- 
found effect, by bringing the patient under the ano- 
dyne influence, by which the action of the ipecac and 
mercury is heightened, two pills can be given every 
hour or two until as many as twelve are taken. To 
avoid nausea, but little water should be allowed soon 
after taking the medicine. 

Bronchitis, Acute. — When called late in the day, 
and it seems advisable to have the patient secure a 
comfortable night's rest under the influence of Dover's 
powder and blue mass, we obtain by this combination 
a twofold action, as it acts both upon the bowels and 
the skin. 

Catarrh, Acute Nasal. — Indicated in place of a 
Dover's powder, and should be followed by gelsemium 
and quinine, to restore the secretions. This plan of 
treatment is well adapted to all bilious cases. 

Colic, Intestinal. — In those cases where the pa- 
tient complains of much pain, associated with costive- 
ness and " biliousness," with a history of constipation 
and diarrhoea alternating, this pill will be found serv- 
iceable. A dose is taken every half-hour until six or 
eight pills are taken. 

Constipation. — Is adapted to the class of cases in 
which morphine is indicated. A pill is given at bed- 
hour, and followed by a drink of cold water in the 
early morning. 

Cough. — Is used as a preliminary to the treatment 
of that form known as " bilious " cough, in which we 
have to contend with stomachal and hepatic disorders. 



ALTERATIVE PILL. 



35 



A pill is taken every hour for six or eight hours, and 
followed the next morning by a saline, unless the bow- 
els are moved naturally. 

Enteritis. — It is adapted to the acute cases, along 
with vascular sedatives, aconite, veratrum, or gelse- 
mium ; when a cholagogue effect is desired, it will 
prove effective. A pill is given every half-hour until 
six, eight, or ten are taken. No poultice should be 
used, but hot-water bottles can be applied front and 
back, which will have a tranquilizing effect upon the 
patient and modify the course of the disease. 

Headache. — Indicated at the beginning of a bilious 
attack. The patient is usually seen in the latter por- 
tion of the day ; a pill is given every hour or half-hour 
until six or eight are taken. 

Influenza. — Adapted to the bilious cases, with 
coated tongue and confined bowels. It allays pain, 
stimulates the liver, and relieves constipation. Six or 
eight pills can be given — one every hour. 

Nervousness. — Persons disposed to biliousness 
are relieved by the ingestion of three or four pills 
shortly before retiring — the bowels to be encouraged 
by the use of small doses of a saline. 

Perspiration. — When occurring in bilious patients, 
a pill is given every hour during the afternoon. 

Phthisis. — Useful to relieve pain, stimulate the 
intestinal glands, and promote a healthy action of the 
bowels. 

Pneumonia. — Very serviceable when the patient 
is bilious ; it should be given during the afternoon or 
evening, to procure sleep, and followed by a saline in 
the morning. Terebene in ten-drop doses every four 
hours is useful in these bilious cases, and is often ef- 
fective in relieving the stubborn cough. 



36 THE POCKET PHARMACY. 



ARSENIC SULPHIDE. 

Each tablet, pill, or granule contains one one-hun- 
dredth grain of the drug. 

Acne. — Its valuable alterative properties recom- 
mend it for the prevention of " bromism," as well as 
for the eruption following the exhibition of potassium 
iodide. A dose should be given every two hours. It 
is especially valuable in chronic acne, simple, and acne 
rosacea. The face should be bathed with some mild 
alkaline wash (tincture of green soap), and the nasal 
cavity thoroughly cleansed daily with the peroxide 
spray. 

Albuminuria. — Arsenic sulphide is a useful rem- 
edy in chronic albuminuria. Commencing early in the 
morning, one pill should be taken every two hours 
until bed-time. 

Alopecia Areata. — May be used with benefit in 
this affection when due to imperfect metabolism. It 
should be employed in connection with iron arseniate 
and the biniodide, in addition to suitable local treat- 
ment. 

Anaemia. — Is used as a preliminary to the employ- 
ment of iron preparations. It may be given with ad- 
vantage in those cases characterized by non-elimina- 
tion, along with the biniodide and quinine. 

Angina Pectoris. — This remedy possesses alter- 
ative properties which commend it to our attention 
for the relief of morbid conditions leading to attacks 
of angina pectoris. It seems to be well adapted to a 
considerable number of cases in which the antispas- 
modic properties of arsenic have been observed ; but in 
cases where we are led to suppose that suboxidation 



ARSENIC SULPHIDE. 



37 



is a factor, the sulphide appears to be more useful as 
an eliminant, and the small dose required precludes 
the danger of accumulation. 

Apoplexy. — It is given here after the subsidence 
of the acute symptoms, to reduce cerebral congestion 
and favor absorption. 

Ascites. — Arsenic sulphide or arsenious acid is 
used in ascites as a cardiac tonic, when the disease 
affects elderly persons. It may be advantageously 
combined with caffeine citrate and alternated with 
apocynum cannabinum. 

Asthma. — The successful employment of arsenic 
in asthmatic conditions and in emphysema is a practi- 
cal illustration of the principles involved in the doc- 
trine of cellular therapy. Arsenic causes fatty degen- 
eration and absorption of morbid products ; in other 
words, it favors elimination by stimulating cell-activ- 
ity. The diseased structures in asthma and emphy- 
sema are favorably situated for this metamorphosis; 
the air-cell is distended, and practically surrounded by 
a rich plexus of capillary blood-vessels. Arsenic, how- 
ever, can be of but slight benefit so long as the blood- 
stream is stagnant or intermittent. Consequently, 
other remedies — trinitrin, strychnine arseniate — must 
be employed to counteract the abnormal condition be- 
fore arsenic can reach the affected structures. The 
arsenic present in the blood is carried to the air-cells, 
where a portion is taken up and acts as a stimulant, 
the result being the discharge of carbonic acid and 
other effete material, the blood in turn taking up any 
oxygen which remains in the cells. Arsenic, by its 
action upon the cells, promotes the reconstructive pro- 
cesses. 

Arsenic sulphide is eminently successful in the 



38 THE POCKET PHARMACY. 

treatment of so-called bronchial asthma with profuse 
expectoration. Alternation with an acid is advisable : 
diluted hydrochloric acid when the conditions indicate 
simple dyspepsia ; nitro-hydrochloric acid when there 
is defective elimination on the part of the liver. Along 
with inhalations and local applications of hydrogen 
peroxide, or ozonized oxygen gas, and the judicious 
employment of strychnine arseniate, great benefit will 
be observed in so-called hay-asthma. 

Atheroma. — It is serviceable in atheromatous con- 
ditions of the cerebral arteries, and may be given in 
combination with ammonium iodide, alternated with 
phosphorus in some form. 

Boils. — When patients are fairly well nourished, 
arsenic sulphide will prevent their recurrence. The 
biniodide and salines are also of benefit in a proportion 
of cases. 

Cerebral Congestion.— Is useful in the early 
stages of atheromatous degeneration, indicated by 
mental hebetude and other symptoms of decay. Phos- 
phorus in some form may be given at the same time. 

Chapped Hands, etc. — When the condition of 
the liver does not indicate defective elimination, this 
unhealthy condition of the integument is often much 
benefited by the internal use of arsenic sulphide, to 
which may be added the local employment of glycerite 
of starch. Five pills are taken daily — one every two 
hours. 

Chicken-pox. — Would commend itself in this dis- 
order, owing to the special influence possessed by its 
ingredients in producing tissue metamorphosis. Chil- 
dren three years of age can take a dose every three 
hours, the skin being kept in good condition by baths, 
and the bowels relieved by salines. 



ARSENIC SULPHIDE. 



39 



Diabetes Mellitus. — Might be supposed to take 
the place of arsenic and calcium sulphide in the treat- 
ment of this disease, but so far I have had no oppor- 
tunity of testing its virtues in this direction. 

Eczema. — Applicable to the chronic, scaly variety, 
but not to the acute cases ; a pill every two hours. At- 
tention must be given to diet and hygiene and the con- 
dition of the bowels. In anaemic cases it will be advis- 
able to alternate this medicament with the arseniate of 
iron, with or without calcium sulphide. 

Fevers. — Might be permitted to take the place 
of small doses of arsenic or strychnine arseniate, de- 
manded from time to time in typhoid conditions. It 
would be especially valuable when an alterative or 
eliminant effect was desired. 

Impetigo. — Useful to change the character of the 
perspiration and favor the elimination of morbid prod- 
ucts. A dose every two hours, with the local use of 
boric acid or aristol. 

Obesity. — Is adapted to that form due to failure 
in elimination. A pill is given every two hours, along 
with one dose daily of mercury biniodide. 

Pemphigus. — Improves the condition of the skin 
and promotes healing. 

Pityriasis. — To be of service it must be continued 
for some time, along with suitable treatment directed 
to the digestive functions. 

Prurigo and Pruritus.— The sulphide may be 
used alone or in combination with mercury biniodide, 
together with the local use of a solution of hydrogen 
peroxide, which should be followed by a dusting pow- 
der of aristol or boric acid. 

Psoriasis. — Should follow the preliminary use of 
the biniodide ; a dose every two hours. In anaemic 



40 THE POCKET PHARMACY. 

cases iron arseniate would be indicated, which should 
be administered after meals. 

Purpura. — All remedies which favor elimination 
of effete material are useful, arsenic sulphide among 
the number, although but little can be accomplished 
without attention to diet and hygiene. 



ATROPINE SULPHATE. 

Each tablet, pill, or granule contains one five-hun- 
dredth grain of the drug. 

Albuminuria, Chronic— Atropine is supposed to 
have a favorable influence upon the inflammatory prod- 
ucts following an acute attack. It may be given along 
with mercury biniodide and arsenic sulphide, one pill 
three times a day. 

Aphonia. — Atropine is of distinct benefit in aphonia 
of the neurotic type. A tablet should be given daily 
in divided (hourly) doses, and physiological effects 
avoided. In addition, the spray or vapor of hydrogen 
peroxide will afford great relief and hasten a cure. 

Asthenopia. — It is used in this affection to pre- 
vent spasm. 

Asthma. — Indicated in spasmodic asthma, to re- 
lieve the paroxysm and act as an aid to the distribution 
of the blood through the peripheral circulation. It 
should be combined with strychnine arseniate and fol- 
lowed by arsenic sulphide. 

Bladder, Irritable. — Is a very satisfactory remedy 
in the treatment of irritable bladder, vesical pain, and 
the incontinence of children. A pill should be given 
three times a day to a child five years of age, fruit be- 
ing restricted at night, and a light diet recommended. 



ATROPINE SULPHATE. 



41 



A tea made from couch grass (triticum repens) will 
often prove serviceable for incontinence in children, 
along with the employment of atropine. 

Boils. — A valuable adjunct to other medication in 
low conditions of the system ; it also lessens pain by 
obtunding the sensibility of the peripheral nerve-end- 
ings. 

Bronchitis, Acute. — Atropine is useful in the early 
stage of acute bronchitis ; in small doses it seems to 
have a "tonic" influence through its action upon the 
respiratory center. Adults take a pill every four 
hours ; for small children, a single pill daily in divided 
(hourly) doses will be sufficient. Atropine and aconite 
should be combined or given in alternation when at the 
onset of the disease laryngitis is present as a complica- 
tion. It is also useful in chronic cases, to lessen the 
secretion of mucus. 

Calculi. — Atropine and morphine hypodermatically 
are used to relieve spasm and quiet pain in renal and 
vesical calculi. In the absence of this, atropine and 
morphine may be used internally. 

Catarrh, Acute Nasal. — Indicated along with 
aconite when the throat is affected. The aconite is 
taken in the usual manner — a pill every ten minutes 
for an hour, then at intervals of an hour; the atropine 
is given in the form of a solution, two tablets being 
dissolved in four ounces of water and given in tea- 
spoonful doses at the same times as the aconite. 

Catarrh, Chronic Nasal. — Is sometimes a useful 
expedient to correct a relaxed condition of the tissues. 
One pill is given every three or four hours for a day 
or two, with directions that it be dissolved in the 
mouth. 

Cerebral Congestion. — Should be used after the 



42 



THE POCKET PHARMACY. 



most active symptoms have subsided, as an aid to in- 
crease the circulation of the peripheral structures, thus 
favoring nutrition by increasing tissue-change. 

Chicken-pox. — When there is sore throat, a child 
three years of age should have one or two pills, dis- 
solved in water, and distributed over the entire day. 
Aconite is added when the pulse is rapid. 

Choking. — The antispasmodic properties of atro- 
pine are well illustrated by the relief it affords in chok- 
ing, either from drinking liquids or from a derangement 
of the nerve-supply of the larynx. Physiological ef- 
fects must be avoided. One or two pills are given 
daily in solution in divided doses. 

Cholera, Asiatic. — For collapse in Asiatic cholera, 
to maintain the circulation, a dose is given every hour 
or two, dissolved in the mouth. Hypodermatic medi- 
cation is more prompt, but the dose must be small. 

Chordee. — May be used with aconite or gelse- 
mium ; a hypodermatic with morphine is rarely re- 
quired. 

Chorea. — It is given in this disease for its sup- 
posed effect upon the peripheral nerve-endings, in con- 
nection with cimicifuga or iron arseniate — a pill two or 
three times a day. 

Colic, Hepatic— Is generally given in combina- 
tion with morphine by hypodermatic injection, followed 
by olive oil, or a heavy purified petroleum oil as soon 
as the stomach will bear it. 

Colic, Intestinal.— Useful in the simple and hys- 
terical varieties, but has no apparent influence upon 
the causation of the disease. 

Colic, Lead. — Given internally will relieve, but 
not so quickly as when used hypodermatically. A dose 
can be given dissolved in the mouth every fifteen min- 



ATROPINE SULPHATE. 



43 



utes until five doses are taken, to be followed by a 
saline in the course of twenty-four hours. 

Constipation. — Is useful when the constipation 
depends upon lack of secretion, as it often occurs in 
persons of a sedentary habit. A pill is given three 
times a day along with a pill of strychnine arseniate. 

Convulsions, Infantile. — On account of its anti- 
spasmodic properties may be used to allay peripheral 
irritation, alone or in combination with the bromides 
or acetanilide compound. 

Cough. — Is used with aconite when there is 
laryngeal or nervous complication ; a dose every four 
hours. 

Croup. — Useful in the early stages in combination 
with aconite. 

Debility. — Is used in small doses when occurring 
in elderly people with low temperature, or in those 
recovering from prolonged illness. A pill is given 
three times a day, along with strychnine arseniate. In 
case the heart is extremely weak, strophanthus may be 
substituted for the strychnine temporarily, and in per- 
sons advanced in years, or those suffering from phthi- 
sis, alcohol should be added. 

Delirium. — Is adapted to that form of delirium 
occurring in fevers dependent upon cerebral anaemia ; 
alcohol and proper aliment are all-important, and in 
addition camphor may be administered. 

Delirium Tremens. — Atropine may be added to 
other treatment to aid in overcoming coma-vigil ; a 
dose every hour or two until five or six doses are 
taken. Hyoscyamus may be substituted when there is 
violent delirium. 

Dentition. — Is of some benefit in preventing con- 
vulsions, although the latter generally depend upon 



44 THE POCKET PHARMACY. 

faulty nutrition, and will disappear with appropriate 
treatment. Anodynes are but temporary expedients. 

Diabetes Insipidus. — Although of some benefit, 
no remedy surpasses ergot in full doses. To maintain 
the improved condition, creasote in pill form, two 
grains three times a day, will be found beneficial. 

Diabetes Mellitus. — Atropine in small doses 
seems to exert a stimulating effect upon the nervous 
system, and is a valuable adjunct to other treatment; 
a dose every three or four hours. 

Diphtheria. — In the early stages of the disease it 
is used to prevent rapid absorption of the poison by 
the affected membranes. Small doses produce suffi- 
cient change in the cells to act as a stimulant, while 
large doses are followed by a corresponding period of 
depression, which leads to the assumption that the tis- 
sues thus affected are less able to withstand absorption. 
A pill should be dissolved in the mouth every hour or 
two until several doses are taken, the temperature be- 
ing taken at regular intervals to determine the prog- 
ress of the disease. It is in these cases that much can 
be accomplished by the judicious employment of the 
spray of hydrogen peroxide, or trypsin, thirty grains 
to the ounce. 

Dysmenorrhcea. — Especially indicated in the neu- 
ralgic form, accompanied by a general debilitated con- 
dition of the system. It may be used conjointly with 
cannabis indica a day or two before the expected 
period. 

Dyspepsia. — A dose three times a day appears to 
exert a favorable action upon the pain, and when given 
along with strychnine arseniate will contribute mate- 
rially to lessen constipation when the secretions of the 
colon are scanty. 



ATROPINE SULPHATE. 



45 



Dysphagia. — Is useful in either the hysterical va- 
riety or that occurring in children from drinking water 
or other liquids. A pill is given three times a day. 

Dysuria. — Adapted to the cases occurring in nerv- 
ous patients. It may be given alone, or in combina- 
tion with the bromides. Sometimes triticum repens — 
a drachm of the fluid extract made in the form of a tea 
and taken two or three times daily — is useful ; the ad- 
dition to it of a small quantity of the tincture of hyos- 
cyamus is valuable. 

Emphysema. — Is used to lessen dyspnoea and the 
profuse secretion of mucus ; it will also counteract any 
spasmodic tendency present. A pill is given every 
four hours along with strychnine arseniate. Inhala- 
tions of pure oxygen gas, five to ten gallons daily, are 
invaluable when this treatment is indicated. 

Enuresis. — Given in moderate doses, in the ab- 
sence of phimosis and marked acidity of the urine, it 
will prove curative. A child five years of age can take 
a pill every four hours on alternate days. 

Epilepsy. — Belladonna has long been known to 
possess decidedly valuable properties in the treatment 
of petit mal and nocturnal epileptiform seizures, owing 
to its sedative action upon the peripheral nerves, but 
is not curative in the true sense of the term. Much, 
however, can be accomplished by its judicious employ- 
ment in connection with the bromides, provided we 
seek to produce only therapeutic effects. It should be 
mentioned here that a combination of ammonium bro- 
mide and antipyrine will prove effective in prolonging 
the intervals between attacks of both petit mal and 
grand mal. In mild cases, occurring in adults, five 
grains of each with elixir of calisaya can be given 
three times a day ; in the severe cases the dose will 



4 6 THE POCKET PHARMACY. 

have to be doubled at first, but may be gradually de- 
creased. A desirable feature of this treatment is that 
it does not produce "bromism" or derange digestion. 

Erysipelas. — Atropine is supposed to have some 
influence upon the progress of the disease, on account 
of its sending a larger quantity of blood to the cutane- 
ous structures, although this has not been practically 
studied. Admitting that the blood-serum possesses 
notable antiseptic properties, it would be reasonable to 
assume that this supposition was correct. 

Erythema. — Is occasionally of service in uncom- 
plicated cases, by increasing the supply of blood to 
the tissues. 

Exophthalmus. — Will have some influence upon 
the progress of the disease when combined with other 
treatment. 

Fever. — Is of special value in the treatment of 
eruptive fevers, scarlatina, measles, etc., and often 
may be used to correct the delirium occurring in sim- 
ple fevers; a dose may be given every three or four 
hours. 

Flatulence. — Atropine may be given along with 
copper arsenite when there is much distention of the 
bowel, accompanied by flatulence occurring shortly 
after eating. A dose of each should be given after 
meals, and diet regulated. 

Flushing. — It is beneficial in the case of young 
women and mothers when the action of the heart dis- 
covers arhythmia, probably due to some fault of the 
nervous system. A pill is taken three times a day. 

Gastralgia. — Allays the pain of gastric ulcer tem- 
porarily, but copper arsenite should be considered on 
account of its antiseptic action. A dose of atropine 
should be taken every four hours. 



ATROPINE SULPHATE. 



47 



Gastric Ulcer. — Atropine is used here in the same 
manner as in gastralgia. 

Glandular Enlargement. — Is sometimes of ad- 
vantage when the tumors occur about the neck, caus- 
ing pain and nervous manifestations. A pill is given 
three times a day. 

Gout. — Is of temporary benefit in allaying the 
pain, but can not take the place of acetanilide compound 
when the condition of the heart will permit of its ad- 
ministration. 

Haemoptysis. — Has the effect of preventing spasm, 
quiets the pain, and strengthens the cardiac action 
without raising perceptibly arterial tension. 

Haemorrhage, Intestinal. — Useful to allay pain 
and promote healing of ulcers situated in the lower 
bowel ; a dose every three hours. Ergot in some form 
should be given in addition. 

Hay-fever. — Prevents the profuse secretion, but 
large doses cause dryness of the throat, which is ex- 
tremely annoying. A pill every four hours seldom 
produces discomfort, and is of material advantage in 
connection with other treatment. 

Headache. — Useful in the headaches occurring at 
the menstrual period in nervous women suffering from 
uterine congestion and ovarian neuralgia. A pill may 
be taken every hour or two until relieved. 

Heart, Fatty. — Is an efficient regulator, acting 
through the motor ganglia, but large doses are contra- 
indicated. A pill is given two or three times a day in 
connection with strychnine arseniate or the arseniate 
of iron. 

Heart, Hypertrophied. — Useful in those cases 
where gelsemium is indicated, to correct palpitation 
and dyspnoea ; a dose two or three times a day. 



48 THE POCKET PHARMACY. 

Heart, Palpitation. — May be used in connection 
with small doses of digitalis — say five drops of the 
tincture and a pill of atropine three times a day. A 
study of the remedies adapted to other cardiac affec- 
tions will indicate the line of treatment best calculated 
to relieve this symptom. 

Heart, Valvular Disease of. — Is of decided bene- 
fit in combination with digitalis, given in the same dose 
and at the same intervals as for palpitation. Large 
doses of digitalis are unsafe in aortic disease ; but in 
small doses, combined with atropine, the untoward ef- 
fect of digitalis is avoided. 

Herpes Zoster. — Is of some benefit in allaying 
pain and quieting the nervous system ; a pill every 
three or four hours. 

Hiccough. — Sufficient must be given to produce 
narcotic effects in severe cases. A dose should be 
given every hour for several hours, then discontinued 
temporarily, small doses of morphine or codeine sul- 
phate being given during the intermission to prevent 
poisoning. These remedies in alternation can be con- 
tinued for several days, although the plan is not recom- 
mended. 

Hysteria. — Atropine is useful in aphonia and other 
nervous manifestations for its general anodyne action ; 
a dose every four hours. 

Inflammation. — Nearly always valuable when 
there is a rheumatic history, and should be given in 
alternation with rhus toxicodendron. A dose of each 
is given every two or three hours, preferably in solution. 

Insomnia. — It is given alone or with morphine 
when there is cardiac irregularity and disturbed vaso- 
motor tension. Two or three doses are taken in the 
evening at intervals of an hour. 



ATROPINE SULPHATE. 49 

Iritis, — May be used internally, but is best applied 
locally; a drop of a solution, one grain to the ounce, 
is placed in the eye, and the biniodide given inter- 
nally. 

Lactation. — Arrests the flow of milk, while pilo- 
carpine and tea increase it. In addition to atropine, 
strong coffee will usually be sufficient to control ex- 
cessive secretion. 

Laryngismus Stridulus.— Will generally be suf- 
ficient to correct the disorder, unless dependent upon 
the presence of worms. For a child five years of age, 
three pills should be dissolved in three ounces of water, 
and a teaspoonful given every hour. 

Laryngitis, Acute. — An excellent addition to aco- 
nite when there is no increased arterial tension ; a pill 
is given every three or four hours, dissolved in the 
mouth. 

Laryngitis, Chronic. — Atropine is useful in small 
doses ; three pills daily, in connection with oxygen in- 
halations and the employment of calcium sulphide, are 
recommended. 

Lumbago. — Is sometimes of value in the begin- 
ning of treatment, for its influence upon the heart and 
the nervous system. A dose three times a day, but not 
to the exclusion of other treatment. 

Mania. — It should be given in connection with the 
bromides, chloral, or chloralamid ; a dose every four 
hours. 

Mastitis. — Is employed to arrest the free secretion 
of milk, along with strong coffee and a dry diet ; a 
dose every four hours. 

Melancholia. — Useful when accompanied by, or 
due to, simple insomnia; a dose is taken every two 
hours for several days. 
4 



So 



THE POCKET PHARMACY. 



Myelitis. — Is not of much benefit, but may be of 
service in connection with ergot or barium chloride as 
indicated ; a dose every four hours. 

Nephritis, Acute, — Used to ease pain, although 
it is but palliative ; a dose every two or three hours. 

Neuralgia. — Useful in the neurotic class of pa- 
tients, where cannabis is indicated ; a pill is given every 
two hours, alone or with cannabis indica. 

Perspiration. — Is of decided advantage in the 
sweating of phthisis ; a dose is given every three or 
four hours, with a hot vinegar bath at bed-hour. 

Pharyngitis. — Used in connection with small doses 
of aconite ; a pill every three or four hours. In rheu- 
matic patients it should be combined with rhus toxi- 
codendron. 

Photophobia. — A drop of a solution, one grain to 
the ounce, should be placed in the eye every few days, 
and treatment conducted in accordance with the indi- 
cations present. 

Phthisis. — Is used to check excessive perspiration ; 
a dose is given every two, three, or four hours for sev- 
eral days — vinegar or a mineral acid in weak solution 
being used as a bath at bed-hour. 

Ptyalism. — A dose should be given every three or 
four hours, a solution of potassium chlorate being used 
frequently as a gargle. 

Scarlet Fever. — Useful when the rash is delayed ; 
along with the use of aconite, it also improves the con- 
dition of the throat. 

Scurvy. — Is used hypodermatically for the saliva- 
tion when the internal administration and local use of 
copper arsenite fail. 

Spermatorrhoea. — Indicated in relaxed conditions 
of the genitalia, alone or in combination with strych- 



ATROPINE SULPHATE. 



5i 



nine arseniate, but physiological effects should be 
avoided. 

Strabismus. — Sometimes useful in overcoming 
convergent squint, but unless a syphilitic history can 
be traced the patient will probably require glasses. 

Syncope.— Is given in purely cardiac cases ; in the 
case of dilatation it should be combined with stro- 
phantus. When arhythmia exists, it is given with 
digitalis ; one pill is taken with five drops of the tinct- 
ure three times a day. 

Testicle, Disease of.— Is useful in neuralgic at- 
tacks accompanying orchitis and epididymitis ; a dose 
may be given every three or four hours. 

Tonsillitis. — Relieves the spasmodic contractions 
of inflamed tissues, and, by arresting slightly the secre- 
tions, the rapid absorption of poisons is prevented. In 
addition, it has a favorable influence upon the terminal 
filaments of the sensory nerves. A dose is given every 
two or three hours. 

Typhoid Fever. — May be given during the stage 
of pyrexia, in case of great prostration, for its influence 
upon the heart and peripheral circulation, and upon 
the tongue ; a dose three times a day when indi- 
cated. 

Typhus. — Indicated to steady the heart and im- 
prove the peripheral circulation, especially the cere- 
bral ; a dose may be given every four hours. Derange- 
ment of the arterial tension (relaxation) may be reme- 
died by giving five drops of the tincture of digitalis 
with each dose. Digitalis, however, must be used here 
with the greatest care, and strychnine arseniate or qui- 
nine may well take its place for the patient's safety; 
it is positively contra-indicated in adynamic conditions. 



5 2 THE POCKET PHARMACY. 



BRYONIA ALBA. 

Each tablet, pill, or granule contains one half minim 
of the tincture, made from the green root according to 
the directions given in the United States Pharmaco- 
poeia for the preparation of green-root tinctures. 

After-pains. — Bryonia is often of great service in 
relieving after-pains. It is adapted to those cases in 
which the peritonaeum is involved, indicated by par- 
oxysmal, lancinating pains; in the absence of clots in 
the uterine cavity, bryonia should be given. In case 
there be a rheumatic history, or symptoms of this dis- 
ease in the subacute form, it will be well to alternate 
it with rhus toxicodendron. With the restrictions 
mentioned, bryonia ought to have a trial before resort- 
ing to hypodermatic medication. A dose is given 
every twenty minutes or half-hour for an hour or two. 

Aphonia. — Is useful in that form of aphonia which 
attacks singers, in which case not infrequently a rheu- 
matic history may be traced. A pill should be dis- 
solved in the mouth every two hours. 

Bronchitis, Acute. — Is a most valuable remedy 
in acute bronchitis ; especially is this true when there 
is much chest-pain, a little sore throat, and great de- 
pression of the vital powers. One pill is dissolved in 
the mouth every hour or two. 

Calculi. — Bryonia might be of service in relieving 
the pains of vesical calculi when indications point to 
implication of the peritonaeum. 

Cerebral Congestion. — It should be given along 
with aconite to relieve pain in the active variety. 

Chest-pains. — Bryonia is one of our best reme- 
dies for the relief of this symptom, these pains being 



BRYONIA ALBA. 53 

for the most part symptomatic. They occur with 
marked severity in pneumonia and pleurisy, but are 
most characteristic in the latter affection. As seen in 
acute, subacute, and chronic bronchitis, they are doubt- 
less due to implication of the fibrous structures in- 
volved, extra- and intra-thoracic. In pleurisy and 
pneumonia the involvement of the serous membranes 
bears a causative relation to their appearance. Usu- 
ally, a pill dissolved in the mouth every hour, or half- 
hour, will subdue them in the course of a few hours. 
Ordinary plasters and poultices and counter-irritants 
should never be employed, as they interfere seriously 
with the normal functions of breathing ; and, besides, 
they destroy the natural protection afforded by the 
cutaneous envelope ; they cause general as well as local 
depression, and are a constant source of danger. 

Cholera, Asiatic. — Bryonia should prove a useful 
remedy for the relief of cramps as they occur in this 
disease, and for which morphine is usually employed. 
In case it fails, codeine should have a trial. 

Colic, Intestinal. — May be used in addition to 
copper arsenite when paroxysmal pains persist — an in- 
dication that the peritonaeum is involved. A dose is 
given every half-hour for several hours. 

Colic, Lead. — The paroxysmal pains occurring in 
this disorder might prove amenable to bryonia — a dose 
every ten minutes for an hour — although a hypoder- 
matic of morphine and atropine would be more certain. 

Cough. — Is useful in convulsive forms of cough, 
when aconite and atropine fail to relieve ; a dose is 
taken every two hours, dissolved in the mouth. With 
rapid pulse, gelsemium is added, both remedies being 
taken together. 

Cystitis. — Employed to relieve the pain due to 



54 THE POCKET PHARMACY. 

vesical contractions in place of morphine and atropine ; 
a pill every hour or two until relieved. 

Diarrhoea. — Used to allay the cutting abdominal 
pains ; a pill is dissolved in the mouth every half-hour 
or hour until relieved. Copper arsenite may be given 
with it as indicated. Codeine does not seem to possess 
any advantage over bryonia in the cases to which the 
latter is adapted. 

Dropsy. — Might be expected to exercise an impor- 
tant influence over dropsies affecting the pericardium 
and peritonaeum, both being serous membranes, and 
hourly doses are recommended. 

Dysmenorrhcea. — Is used in the class of cases to 
which aconite is adapted, to allay paroxysmal pains. 
With a rheumatic history, cimicifuga in small doses is 
efficient in both dysmenorrhoea and amenorrhoea. 

Dyspepsia. — A useful remedy for the paroxysmal 
headaches known as ' bilious" headaches. It also has 
a favorable action upon the condition of the stomach, 
owing to its bitter principle. A dose is taken every 
half-hour until relieved. 

Empyema. — Useful principally as a prophylactic 
in the early stages of the inflammatory process ; a dose 
is given at intervals of an hour, or oftener if required. 

Endocarditis. — Given in small doses, it may serve 
as a preventive when pericarditis is threatened. A 
dose is given every two or three hours, along with aco- 
nite or gelsemium. 

Enteritis. — Indicated when the disease is accom- 
panied by sharp, lancinating pains, showing that the 
peritonaeum is involved. A dose is given every half- 
hour at first, then hourly as required. 

Epilepsy. — Is useful in those cases preceded or 
followed by sharp, lancinating headache, when the 



BRYONIA ALBA. 



55 



membranes are involved in the morbid changes due to 
the disease; it is, however, only a palliative remedy, 
although with other treatment it may serve to lengthen 
the intervals. 

Gastralgia. — Indicated when the pain is paroxys- 
mal and sharp, along with a rheumatic history. A 
dose is taken every hour or two for one or two days. 

Glaucoma. — May be used in connection with gel- 
semium to relieve the pain and reduce tension ; a dose 
every two hours. 

Gonorrhoea. — May take the place of bromides to 
relieve the pain of chordee; a dose every hour or two. 

Hay-fever. — Used to control chest-pains, and pre- 
vent the extension of the disease ; a dose every hour 
or two dissolved in the mouth. 

Headache. — Bryonia is a useful remedy in bilious 
headache, when the pain is of a lancinating character 
—an indication that serous membranes are affected ; 
it is much superior to aconite, although a rapid pulse 
indicates the addition of aconite or gelsemium to the 
treatment. 

Hepatitis. — Relieves the lancinating pain, and 
probably has some stimulant action upon the liver, al- 
though its physiological action in small doses is not 
very well understood. A dose is taken every hour. 

Hydrocephalus, Acute. — It ought to be effective 
in this disease, owing to its influence upon serous 
structures. Along with this, a supportive plan of treat- 
ment should be adopted. 

Hydrothorax. — Used in the early stage to pre- 
vent effusion ; a dose every hour. 

Inflammation. — Useful in all cases where serous 
membranes are involved, but the pulse-rate should be 
lowered by aconite or gelsemium before beginning its 



56 



THE POCKET PHARMACY. 



administration. Both remedies can be given at the 
same time. 

Influenza. — Should be employed to relieve the 
chest-pains, headache, and oppression ; a dose every 
hour for several hours. 

Irritability. — Bad temper is often due to conges- 
tion of the cerebral meninges, or derangement of other 
serous membranes, and may be favorably influenced 
by small doses of bryonia. 

Lumbago. — Useful in the class of cases in which 
the muscular fasciae are involved, indicated by a more 
or less constant pain. A dose every hour, but no poul- 
tices or adhesive plasters. 

Meningitis, Cerebral. — It is employed to lessen 
pain and prevent effusion ; a dose every half-hour or 
hour according to the age of the patient. 

Myalgia. — Indicated when the pain is constant, or 
when it is quite as severe when the patient is quiet as 
when moving about — an indication that the fasciae or 
sheaths of the muscles are affected. A dose may be 
given every two or three hours. 

Pericarditis. — To lessen the tendency to exuda- 
tion, and to arrest it when begun ; a dose every hour 
or two, alone or with atropine. 

Peritonitis. — Acts here as in the case of inflam- 
mation affecting other serous membranes ; it serves to 
lessen pain and prevent exudation. A dose may be 
given every hour. 

Phthisis. — Occasionally it is a prompt reliever of 
chest-pains; a pill is given every hour or two. 

Pleurisy. — A most valuable medicament to allay 
pain and prevent effusion. The chest must be prop- 
erly bandaged, and a dose given every hour or half- 
hour at first. 



BRYONIA ALBA. 



57 



Pleuro - pneumonia. — Very useful in the early 
stages along with acetanilide compound. A dose of 
each is given every hour for several hours, after the 
activity of the pulse has been subdued by the admin- 
istration of aconite or gelsemium. 

Pneumonia. — Is used to lessen pain and counter- 
act the tendency of the disease to involve the pleura. 
A dose is given every hour or two in connection with 
other suitable treatment. 

Rheumatism, Acute. — Indicated for the relief of 
joint-pain and cardiac pain, and is believed to possess 
valuable properties in preventing effusion ; a dose is 
given every hour or two. The local use of oil of 
winter-green and soap liniment, equal parts, may be 
added to the treatment with advantage. 

Rheumatism, Chronic. — Is often useful to allay 
pain in a joint, due to an inflamed condition of the 
synovial membrane, indicated by pain when the joint 
is at rest ; a dose every hour or two. 

Synovitis. — Very useful in the acute stage, the 
joint being kept at rest. Poulticing, counter-irritation, 
and other local measures must be avoided, if we expect 
good results to follow. An evaporating lotion is some- 
times of benefit, if properly employed, but as a rule it 
will be found that applications of this character will 
be converted into a poultice. In subacute and chronic 
cases, however, absorbents are indicated, and may 
serve a useful purpose. 

Tympanites. — Relieves the pain, but does not 
strike at the true cause of the malady. It should be 
combined with creasote or vegetable charcoal in sim- 
ple cases, with a view to correct derangements due to 
fermentation of food. 

Typhoid Fever. — Is often useful to allay the pain 



58 



THE POCKET PHARMACY. 



due to tympanites, although it is not curative It also 
relieves promptly the peculiar headache to which it is 
adapted, and on the whole is a very desirable remedy. 
Probably other indications will be found for it in the 
near future. 

CALCIUM SULPHIDE. 

Each tablet, pill, or granule contains one-tenth grain 
of the drug. 

Abscess. — Is used here to arrest the formation of 
pus by the disease invading new tissue ; after opening, 
it favors healing and lessens the discharge, local anti- 
sepsis being strictly maintained. 

Acne. — It is used in the treatment of acne in al- 
ternation with arsenic sulphide. The latter is most 
useful where quinine and iron appear to be indicated, 
while the former seems to answer better where a he- 
patic stimulant, such as the biniodide, is required. In 
obstinate cases, sulphur, phosphorus, or cod-liver oil 
may be added to the treatment ; and the general con- 
dition of the skin must not be overlooked. 

Amenorrhoea. — Useful in that form of amenor- 
rhea dependent upon anaemia and functional inactivity 
of the ovaries. Benefit will follow its combination 
with iron arseniate and quinine. A dose should be 
given three or four times a day. 

Balanitis. — A pill three times a day along with 
the local use of a solution of the peroxide of hydrogen, 
one part to ten, or a saturated solution of boric acid, 
will produce very satisfactory results. 

Blepharitis. — In this affection it is given inter- 
nally in connection with suitable local treatment. 

Boils. — When properly used, in connection with 



CALCIUM SULPHIDE. 



59 



the biniodide, it will arrest the formation of boils when 
they show a disposition to come in crops. Five or six 
pills are taken daily, at intervals of two hours. No 
remedial measures can be calculated with greater cer- 
tainty than this method of treatment, provided local 
applications are omitted until the boil is opened with 
the lance under proper antiseptic precautions. The 
value of poultices has been over-rated ; as generally 
employed they are worse than useless, and it would be 
far better to abandon their use altogether. Iron ar- 
seniate is required in strumous subjects after the first 
few days of treatment. 

Bronchiectasis. — It will produce favorable effects 
in this affection, given in combination with iron ar- 
seniate after the use of quinine, creasote, or terebene. 
Inhalations of pure oxygen gas are most satisfactory 
in connection with internal medication. 

Bronchitis, Acute. — Should be used in acute bron- 
chitis, after the most active symptoms have been sub- 
dued by appropriate medicaments — say, after the first 
twenty-four hours. A pill is given every hour or two. 

Bubo. — It is valuable in the treatment of bubo, 
after a few days' treatment with the biniodide, to check 
suppuration and promote healing. 

Carbuncle. — It will arrest or abort the disorder in 
the formative period, if given in connection with sa- 
lines ; a pill is taken every hour or two, with a saline 
in the morning. Poulticing precipitates the formation 
of pus. Calcium is indicated where there are no marked 
digestive disturbances ; the biniodide when these exist. 
Calcium is always indicated after the discharge of pus 
begins, but tonics, quinine, iron, etc., may be added 
with advantage. 

Caries. — Is useful in the incipient stage, before 



60 THE POCKET PHARMACY. 

necrosis has taken place, and is recommended in addi- 
tion to the local use of the clay dressing. 

Cerebritis. — Is useful to avoid the formation of 
abscess. The author has seen one marked case of 
brain injury in which there could be no doubt of the 
breaking down of tissue, where calcium sulphide in 
time caused the disappearance of all symptoms. 

Chlorosis. — When we have to deal with chlorotic 
patients showing symptoms of cutaneous eruptions, no 
remedy promises greater benefits than calcium sulphide 
in connection with iron arseniate, and the occasional 
use of the biniodide. A pill should be given three 
times a day ; larger doses are liable to derange the 
digestion, and the patient will object. Purified petro- 
latum, with or without a percentage of paraffin, often 
exercises a curative effect through its antiseptic, solv- 
ent, and lubricating properties. A tablespoonful may 
be taken twice daily about an hour after meals. Cod- 
liver oil and the digestive ferments may also be called 
to our assistance, but they are of secondary importance 
until the habit has been overcome. 

Choroiditis. — Is useful to arrest pus-formation, 
alone or with small doses of gelsemium. 

Colic, Lead. — Is of service in restoring a healthy 
condition of the mucous structures after an attack, 
which it does by favoring the elimination of inflam- 
matory products ; a dose every four hours. 

Conjunctivitis. — A dose is given every two hours, 
with antiseptic lotions, hot or cold, of hydrogen perox- 
ide, which should be followed by the local application 
of purified petrolatum containing a percentage of par- 
affin wax. 

Corneal Opacities. — Useful to correct the tend- 
ency to the breaking down of tissue; the addition of 



CALCIUM SULPHIDE. 6l 

the local use of a heavy petrolatum oil containing a 
percentage of paraffin produces a protective for the 
affected membrane. A single drop liquefied by heat 
may be placed in the eye night and morning. 

Cough. — Indicated when there is profuse secretion 
and constant throat irritation, along with morphine 
hydrochlorate or one-tenth grain of codeine sulphate ; 
a dose of each is given at intervals of an hour or two. 

Croup. — It is effective when the membranous form 
threatens; a pill is given every hour along with mer- 
cury biniodide two or three times a day for its anti- 
septic influence. It is in these cases that we can ob- 
tain great benefit from the use of the spray of a solution 
of hydrogen dioxide (Marchand's). Ipecac is also 
indicated to favor the expulsion of membrane in the 
formative stage, but it is unnecessary to produce 
emesis. 

Deafness. — When due to catarrh of the middle ear 
or of the mastoid cells, calcium sulphide, along with 
an occasional dose of the biniodide, is indicated. A 
pill is taken every two or three hours ; cupping, Baun- 
scheidtismuS) or some other form of counter-irritation, 
may aid in restoring the hearing. 

Diabetes Mellitus. — Calcium is a valuable rem- 
edy in connection with arsenic and codeine in this 
affection. It should be given, a dose every two hours, 
along with one-fifth grain of codeine sulphate, gradu- 
ally increasing the dose of the lat f er, and substituting 
for it from time to time creasote in full doses. 

Dysmenorrhea. — This remedy should always be 
given when evidences of catarrhal changes are pres- 
ent. As a means of arresting inflammatory action, and 
favoring the absorption of pus in closed cavities, as in 
ovaritis, salpingitis, etc., no remedy is so valuable as 



62 THE POCKET PHARMACY. 

calcium sulphide. It must, however, be given in small 
doses, and in addition the oxyhemoglobin must be im- 
proved by the administration of iron, as without haema- 
tinics in anaemic conditions it fails to produce the de- 
sired effects. Five pills can be given daily — one every 
two hours. 

Earache. — Indicated in those cases with nasal 
catarrh, and symptoms of extension to the middle ear 
through the eustachian tube ; a dose is given every 
two hours, alone or in combination with gelsemium, to 
reduce the activity of the circulation. This treatment 
is followed by the exhibition of quinine. 

Eczema. — Calcium sulphide and sulphur are less 
efficient in the early stages, but serve a useful purpose 
after the employment of rhus or the biniodide, when 
dyspepsia has been overcome. While it would not be 
prudent to attempt a discussion of a suitable dietary 
for eczematous patients, the observation is warranted 
that many cases are due to the ingestion of improper 
food ; oatmeal and potatoes should be prohibited for a 
time at least. 

Empyema. — Is of equal value here as in other 
suppurating diseases ; a dose is taken every two 
hours along with quinine, followed by symptomatic 
treatment. 

Endometritis. — Along with suitable doses of the 
biniodide, and appropriate local treatment, it will ma- 
terially cut short the usual course of the disease. 

Enteritis. — Is useful in the chronic cases and dur- 
ing the period of convalescence, along with iron ar- 
seniate ; a dose of each is taken every four hours. 

Glanders. — Would be indicated after the subsi- 
dence of acute symptoms ; a dose every two or three 
hours. 



CALCIUM SULPHIDE. 63 

Glandular Enlargement. — Is best suited to those 
cases having a short course in their origin and devel- 
opment, in which there are no pronounced evidences 
of sepsis. It may be given with iron arseniate — a dose 
of each every three hours. 

Gout. — Useful in chronic cases along with quinine, 
or in alternation with biniodide ; a dose is taken every 
two or three hours. Alkaline and sulphur waters are 
especially indicated, with mud-baths. 

Gums, Spongy. — Will restore the healthy condi- 
tion of the mucous membrane when the disorder is of 
a local character ; a pill is taken every three or four 
hours. 

Inflammation. — Valuable in nearly all cases after 
the pulse-rate is reduced, to prevent the formation of 
pus and restore a healthy condition of the affected 
tissues and membranes ; a dose is taken every three 
or four hours. 

Iritis. — Has a favorable influence in restoring the 
secretions and causing absorption, after the subsi- 
dence of acute symptoms ; a dose every three or 
four hours. 

Laryngitis, Acute. — Useful to correct unhealthy 
secretions, along with aconite, to reduce arterial ten- 
sion ; a dose every two or three hours. Oxygen inha- 
lations are invaluable. 

Leucorrhcea. — May be used alone or in combina- 
tion with iron. Relieves ovarian and uterine pain due 
to passive congestions, and contributes toward the res- 
toration of the healthy secretions. 

Lichen. — A dose is taken every four hours, or, 
in its place, arsenic sulphide is given in chronic 
cases. 

Mastitis. — Useful to prevent the formation of pus. 



64 



THE POCKET PHARMACY. 



A pill is given every hour or two, but poultices must 
be prohibited. Dry heat is applied in severe cases, in 
addition to the use of a tight-fitting bandage. 

Otorrhcea. — A very efficacious remedy, at almost 
any stage — acute, subacute, or chronic. A pill is taken 
every hour or two and dry dressing applied — boric 
acid or aristol. 

Ovaritis and Neuralgia.— Should be given a fair 
trial, first alone, then in combination with iron arsen- 
iate ; a dose of each every two hours. 

Ozsena. — Useful in the majority of cases in con- 
nection with local antiseptic applications. A pill is 
taken every three hours in connection with the spray 
of hydrogen peroxide, or a solution of arsenite of cop- 
per. Patients should never be allowed to use the nasal 
douche. 

Paronychia. — If taken in time will abort, provid- 
ing the activity of the circulation is subdued by appro- 
priate medication. A pill is taken every hour or two, 
the parts being supported by a clay dressing kept con- 
stantly moist. 

Pemphigus. — Has a tendency to correct the ab- 
normal condition of the blood which favors the forma- 
tion and discharge of matter. It may be given in con- 
nection with iron arseniate. 

Pertussis. — Of value after the subsidence of the 
acute symptoms. A dose may be given three or four 
times a day to a child four years of age. 

Pharyngitis. — Useful in both the acute and sub- 
acute stages of the disease, along with vascular seda- 
tives ; a dose three or four times a day. 

Phthisis. — May be given with advantage in the 
absence of high temperature ; a dose every three hours. 
It favors expectoration, but not at the expense of the 



CALCIUM SULPHIDE. 65 

patient's strength ; it may be combined with iron ar- 
seniate with benefit. 

Pneumonia. — Useful in the later stages of the dis- 
ease, alone or in combination with iron arseniate when 
there is marked anaemia ; a dose of each may be given 
every four hours. 

Prostatitis. — Used in the early stages along with 
aconite to reduce the activity of the circulation ; the 
free use of hot enemata is recommended. 

Prurigo and Pruritus. — Will prove effective in 
correcting unhealthy mucous secretions upon which 
the disorder often depends, in connection with suitable 
local treatment ; a dose every three hours. 

Psoriasis. — Is well calculated to relieve, and aid 
in effecting a permanent cure. The arseniate of iron 
will prove a valuable adjunct. 

Ptyalism. — Useful in the later stages — say, after 
the exhibition of nitric acid and atropine ; a dose three 
or four times a day. 

Pyelo-nephritis. — A dose is taken every two 
hours along with some non-irritating diuretic, such as 
triticum repens. 

Rheumatoid Arthritis. — Is sometimes given, but 
is less valuable than sulphur; a dose is taken every 
two hours in connection with other medication. 

Scabies. — Should be used in connection with suit- 
able local treatment ; a dose every three hours. 

Scrofula. — Is sometimes advantageously alternated 
with the biniodide. It may be given alone or in com- 
bination with the arseniate of iron ; a dose of each 
every three hours. 

Seborrhcea. — Should be used in connection with 
iron when the latter can be borne, together with suit- 
able local treatment. 

5 



66 THE POCKET PHARMACY. 

Sterility. — Has proved successful in overcoming 
sterility due to chronic leucorrhoea. The antiseptic 
douche, hot water, or a solution of the peroxide, should 
be regularly adopted. 

Suppuration. — Very useful in all non-specific 
cases, although it is not really an antiseptic. Many of 
the cases in which pus occurs in closed cavities can be 
relieved by the internal administration of calcium sul- 
phide, because pus in many instances has lost its patho- 
genic character, and is non-toxic ; pyosalpinx, pyelo- 
nephritis, and pleurisy with effusion and peritonitis 
furnish evidences to confirm this statement ; and the in- 
vestigations of Prof. Roswell Park supply ample proof. 

Synovitis. — In addition to strapping, bandaging, 
or the application of the clay dressing, calcium sulphide 
will be useful toward the end of the acute stage ; a 
dose every two or three hours. 

Syphilis. — Useful sometimes in alternation with 
mercurials or potassium iodide, for the purpose of re- 
storing a healthy condition of the mucous membranes. 

Tinea Favosa. — Arrests suppuration and favors 
healing, when combined with appropriate local treat- 
ment. 

Tonsillitis. — Is adapted to the ordinary class of 
cases which are usually seen by the physician too late 
to be arrested. In connection with suitable symptom- 
atic treatment, it will promote healing by arresting or 
controlling suppuration. 

Toothache. — Adapted to those cases in which ab- 
scess threatens, if taken in the early stages. Dry heat 
is applied cautiously, and a pill given every hour for 
several hours. 

Typhlitis. — Promises better results in connection 
with the local use of dry heat than morphine. The 



CALCIUM SULPHIDE COMPOUND. 



6 7 



lower bowel should be relieved by enemata, hot water, 
or a saline solution ; and it may be deemed advisable 
to apply leeches to relieve congestion. 

Typhoid Fever, — Should be employed after the 
disappearance of the morning rise of temperature ; a 
dose three times a day has a very happy effect upon 
the mucous membrane. 



CALCIUM SULPHIDE COMPOUND. 

Formula : IJ, Morphinae hydrochloras, ) - - x . 
Pilocarpine hydrochloras, ) 

Calcii sulphidi gr. %. 

Misce et fiat pilula vel tab. trit. no. j. 
Bronchitis, Acute. — This combination is espe- 
cially adapted to the treatment of acute bronchitis, 
after the active symptoms have been subdued by ap- 
propriate medication. It is indicated also to overcome 
those obstinate cases occasionally met with where there 
is a persistent dry cough, great depression, and ano- 
rexia ; the entire system appears to suffer. By bring- 
ing the cough slightly under subjection by morphine 
and stimulating the secretory function of the pulmo- 
nary and bronchial structures by pilocarpine, together 
with the criminative action of calcium sulphide, great 
relief accrues to the patient. The compound was 
originally intended for children, but the difficulty and 
expense attending its extemporaneous preparation 
prompted me to have it put in the convenient form 
now offered. A child five years of age can take a pill 
every hour or two, gradually extending the intervals; 
adults usually do well on one pill every hour, but two 
every hour can be given at the beginning of treatment. 



68 THE POCKET PHARMACY. 

Catarrh, Acute Nasal. — In the absence of fever 
and increased rapidity of the pulse, calcium compound 
may be relied upon to cut short an attack. In addi- 
tion, the peroxide spray will prove efficient. 

Cough. — Is very useful to combat those forms of 
cough which occur so frequently in persons suffering 
from subacute and chronic bronchitis. One or two 
pills can be taken at intervals of an hour or two, ac- 
cording to the demands of the disease and the effect 
upon the patient. It will be found less objectionable 
than the old-style cough mixtures, and far more effi- 
cacious, because it does not tend to arrest the normal 
secretions. With cod-liver oil, creasote, and good nour- 
ishment, it will prove very acceptable. It is best 
adapted to the dry, hoarse variety of cough. 

Influenza. — Is adapted to the early stages of the 
disease, after the exhibition of aconite or gelsemium, 
to allay pain and promote secretion ; and as it does 
not mask the real character of the disease, it will not 
interfere with other medication. It may be used in 
connection with quinine and creasote. 

Pertussis. — Useful after the employment of gel- 
semium or drosera, to improve the character of the 
pulmonary and bronchial secretions. A dose may be 
given every hour or two to a child five years of age. 

Phthisis. — Useful in the place of cough mixtures, 
and much less disagreeable ; a dose every hour or two. 
It can be put in a capsule with other medicaments. 

CALOMEL. 

Each tablet, pill, or granule contains one-twentieth 
grain of the drug. Thorough trituration is necessary 
before making up into pills. 



CALOMEL. 



69 



Ascaris Lumbricoides. — It is used in this affec- 
tion in combination with santonine ; a tablet of calo- 
mel and one containing one-tenth grain of santonine 
are given every hour for six or eight hours, fasting, to 
be followed the next morning by a saline. This treat- 
ment is repeated every third day until the medicine 
has been taken three separate times. 

Ascites. — Calomel possesses valuable diuretic 
properties in cardiac dropsy, but its use should be con- 
joined with the employment of a saline. 

Biliousness. — Calomel for children is probably 
equal to the alterative pill for adults in the case of 
biliousness, but the indications for calomel are not al- 
ways so clear as for the use of the pill. Simple meas- 
ures will often relieve a most threatening attack in 
these little ones. Very frequently the causes are pa- 
tent; indigestion, followed by fermentation and the 
production of poisonous ptomaines, are mainly respon- 
sible for biliousness in children, for which copper ar- 
senite is a sovereign remedy. The employment of calo- 
mel as a purgative for children is rarely indicated, but 
it is of decided benefit when we have to deal with a gen- 
eral derangement of the entire alimentary tract. Gray 
powder in the same dose is probably equally as efficient 
as calomel, but its range of application is restricted. 

Cholera, Asiatic. — Calomel has been recommend- 
ed to allay vomiting, but it does not promise so well 
as copper arsenite. 

Cholera Infantum. — It has been recommended in 
minute doses to arrest vomiting, but is not so effective 
as copper arsenite. It is sometimes useful, however, 
when the mercurial effect is indicated ; a pill every 
two hours until five or six doses are taken. 

Diarrhoea. — Indicated for its influence upon the 



7° 



THE POCKET PHARMACY. 



liver ; either the gray powder in doses of a grain every 
hour for five hours, or calomel one-twentieth in the 
same manner, to subdue colitis following attacks of 
diarrhoea and dysentery — specially indicated with light- 
colored, pasty stools. This alone, however, is insuffi- 
cient ; copper arsenite in solution should be used to 
flush the colon, once or twice daily. Ipecac internally 
is well adapted to follow this treatment. 

Fever. — Calomel is often of service in the early 
stage of simple fever occurring in children, and in 
adults when there is a history of a bilious condition. 
It is also useful in the prodromal stage of typhoid, or 
suspected typhoid with complications. A dose is given 
every hour until eight or ten pills are taken. When 
there is much abdominal pain, the alterative pill may 
be substituted. 

Fissure of the Anus. — Calomel has been recom- 
mended for the relief of fissure of the anus as an oint- 
ment with lard, but aristol and iodoform have sup- 
planted its use in this disorder. 

Hepatitis. — It has long held a deservedly high 
position in the treatment of nearly all derangements 
of the hepatic function, but it is less active as a hepatic 
stimulant than the biniodide ; the latter is therefore 
entitled to occupy first place as an hepatic stimulant 
in anaemia as a preliminary to the administration of 
iron or quinine. 

Jaundice. — Useful along with salines in children ; 
a dose is given four or five times a day. 

Syphilis. — Sometimes used in the preliminary treat- 
ment — a solution of chromic acid being applied to the 
ulcerations in the mouth. Jonathan Hutchinson speaks 
highly of small doses of gray powder in the treatment 
of this disease. 



CAMPHOR. 



71 



Thread-worm. — Should be combined with an 
equal quantity of santonine, and a dose given at inter- 
vals of three hours for a period of three days; this 
treatment is repeated three days later. Along with 
this should be combined the use of salt and water or 
an infusion of quassia as an enema ; a solution of cop- 
per arsenite has also been found effective. 

Typhoid Fever. — Must be given in such dosage 
in this disease that stomatitis is liable to follow its use. 
It has little antiseptic power, and is useful only on 
account of its effect upon the contents of the intestine. 
Undoubtedly it favors the discharge of bile, and will 
be found beneficial occasionally when there is consti- 
pation, along with suitable enemata. Creasote will 
prove useful when calomel is employed, but carbolic 
acid, never. 

CAMPHOR. 

Each tablet, pill, or granule contains one-fourth 
minim of a saturated tincture. 

After-pains. — Is a valuable nervine and stimulant, 
and may be used in the class of cases in which arsenite 
of copper is indicated ; a dose every ten minutes for 
an hour or two. 

Ascaris Lumbricoides. — After fasting for twenty- 
four hours, a pill should be taken every ten minutes for 
an hour or two, then at less frequent intervals, the pa- 
tient being restricted to a milk-diet. 

Asthma, Spasmodic. — Is indicated in spasmodic 
asthma to meet profound depression ; a dose is given 
every ten minutes for an hour, then at less frequent 
intervals. 

Breath, Fetid. — Camphor is of service in fetid 



72 



THE POCKET PHARMACY. 



breath, but a solution of the peroxide of hydrogen is 
far more prompt and satisfactory. Two drachms in 
half a goblet of water should be taken through a glass 
tube. It is best adapted to catarrhal conditions of the 
stomach with indigestion. 

Bronchitis, Capillary.— Useful for its stimulant 
and tonic effect, and when indicated the iodides are 
used. 

Cerebral Anaemia. — In simple cases of cerebral 
anaemia is often a sufficient tonic to overcome derange- 
ments of the vascular tone. It has the advantage of 
being prompt in producing effects. 

Cholera, Asiatic. — Is of value as an aromatic 
stimulant and nervine, and should be given a pill every 
ten minutes in connection with the employment of cop- 
per arsenite. 

Cholera Infantum. — May be given in solution, 
alone or in combination with a little chloroform, as a 
stimulant when there is great depression. 

Chordee. — Should be used when there is much 
depression ; a dose every hour along with atropine. 

Climacteric Disorders.— Is sometimes service- 
able for the drowsiness, but is of temporary value only, 
as this condition depends upon disorders of vascular 
tension, often of hepatic origin. 

Colic, Intestinal. — Like all aromatic substances, 
it has a tendency to overcome the effects of fermenta- 
tion ; but all are unsatisfactory. 

Delirium. — Is used with atropine in low conditions 
of the system, such as we meet in pneumonia, typhoid, 
and typhus; a dose every ten minutes for an hour 
or two. 

Diarrhoea. — Useful to combat profound depression. 

Dysmenorrhcea. — Sometimes of benefit in nerv- 



CAMPHOR. 



73 



ous subjects as a nervine, although it has no effect 
upon the course of the disorder; a dose may be given 
every hour. A better plan is to combine it with cimi- 
cifuga, which is useful in rheumatic patients when used 
in minute dosage. 

Dysuria. — Useful in low conditions of the system, 
in conjunction with other treatment. 

Fever. — Is used to quiet delirium and give tone to 
the nervous system and digestive apparatus, and is well 
adapted to adynamic fevers. One or two pills are 
taken every hour or two. 

Flatulence. — Is often, but not always, useful in 
hysterical cases and at the climacteric ; a dose is given 
every hour. It may be combined with atropine with 
benefit. 

Haematuria. — Suited to meet attacks occurring in 
nervous patients ; a dose every half-hour. 

Headache. — Indicated as a palliative in persons 
who are bilious and who suffer more or less from slow 
digestion and flatulence ; a pill is taken every ten min- 
utes for an hour. 

Heart, Hypertrophied. — May be used in place 
of atropine to allay excitement ; a dose every two 
hours. 

Hysteria. — It is sometimes given in large doses to 
quiet excitement, in which case the narcotic effects are 
desired. 

Insomnia. — Adapted to the debilitated, nervous, 
and dyspeptic, in which case it acts in a manner similar 
to strychnine ; a pill every half-hour for several hours 
before retiring. 

Measles. — Useful to meet the depression following 
the subsidence of the active stage of the disease; a 
dose is given every hour or two. 



74 



THE POCKET PHARMACY. 



Nephritis, Acute. — A palliative nervine, and may 
be used occasionally with benefit ; a dose every ten 
minutes for an hour. 

Nymphomania. — Large doses are indicated in this 
affection ; two or three pills every half-hour for sev- 
eral hours, with cold vaginal douche and hypnotics to 
procure sleep. 

Phthisis. — An acceptable carminative, and has a 
good effect upon the nervous system ; a pill every 
hour or two. Camphorated oil — one part camphor to 
nine parts olive oil — has been used hypodermatically 
by Bruno Alexander, of Berlin, with good results in 
the treatment of respiratory diseases. It was found 
especially valuable in the later stages of phthisis, in 
haemoptysis, bronchitis, and pneumonia. The dose 
employed is fifteen minims once daily for a period of 
four days, after which the injections are to be omitted 
for a week, on account of the cumulative action, mani- 
fested by headache and restlessness at night. 

Puerperal Convulsions. — May be of value to 
counteract depression, but is not curative. Pilocarpine 
hypodermatically is curative when due to uraemic poi- 
soning, although veratrum is a favorite remedy with 
some physicians. 

Puerperal Mania. — May be employed in connec- 
tion with bromides, chloral, cannabis indica, hyoscya- 
mus, or stramonium. 

Pyrosis. — Of temporary benefit only ; a pill may 
be given every ten or fifteen minutes until relieved. 

Sexual Excitement. — Given in substantial doses, 
will subdue, but the bromides are superior. 

Spermatorrhoea. — Diminishes venereal excite- 
ment when used in considerable dosage continuously. 
A hot douche on retiring is preferable to cold water. 



CANNABIS INDICA. 



75 



Syncope. — Is both a cardiac and respiratory stimu- 
lant, and should be given freely, alone or with spirits 
of chloroform, in a large class of debilitated and hys- 
terical subjects. 

Typhus. — Indicated for its effect upon the general 
nervous system. 

Yellow Fever. — Should be used in frequent small 
doses for its stimulating action upon the nervous sys- 
tem in this as in all adynamic conditions ; a dose may 
be given every fifteen or twenty minutes. 



CANNABIS INDICA. 

Each tablet, pill, or granule contains one- twentieth 
grain of the extract of cannabis indica. 

Appetite, LOSS of. — Even in moderate dosage 
cannabis produces marked effects in simple loss of 
appetite — a condition frequently noticeable after pro- 
longed illness ; a dose is taken every two or three 
hours. 

Asthma. — It is useful in chronic asthmatic condi- 
tions; it overcomes tendency to spasm, improves the 
appetite, stimulates the vital centers, and creates a 
feeling of well-being ; a dose is taken every hour 
or two. 

Bladder, Disease of. — Is said to be useful in re- 
tention of urine due to spinal disease; a dose every 
two hours. 

Bronchitis. — Is a valuable remedy in old cases of 
chronic bronchitis ; it lessens the cough and promotes 
expectoration. 

Cholera, Asiatic. — On account of its influence 
upon the abdominal viscera, acting through the cere- 



76 THE POCKET PHARMACY. 

brum, it will be of benefit in this disorder. It may 
be given in combination with camphor ; a dose every 
ten minutes for an hour, then at less frequent inter- 
vals. 

Chordee. — Is used here to counteract the mental 
depression occasionally seen in neurotic patients ; in 
connection with gelsemium, a dose should be given 
every two hours. 

Chorea. — Sometimes increases the movements, but 
may be tried in small doses in connection with iron 
arseniate ; a dose of each every three hours. 

Climacteric Disorders. — A pill is taken every ten 
minutes for an hour, then hourly, to relieve what may 
be termed panphobia — an indefinable dread of impend- 
ing danger. It is especially valuable to correct flut- 
tering of the heart. 

Cough. — Sometimes of signal service in reflex 
cough of uterine and ovarian origin. A pill is given 
every ten minutes for an hour, then hourly until relief 
is afforded. It is of service also in asthmatic cough, 
along with teaspoonful doses of grindelia robusta, at 
intervals of three hours. 

Debility. — Useful when dependent upon onanism, 
in which case a dose is given every hour, along with 
strychnine arseniate in small doses. 

Delirium. — Especially valuable in that form due 
to lesions of the brain structure, but may also be used 
when other remedies are contra-indicated by the con- 
dition of the digestion. 

Delirium Tremens. — The treatment of this will 
be conducted in accordance with the age and physical 
condition of the patient and the stage of the disease. 
Generally speaking, cannabis indica and strychnine 
arseniate are both indicated for their combined influ- 



CANNABIS INDICA. 



77 



ence upon the brain, the stomach, and vaso-motor sys- 
tem. Cannabis always exercises a prompt amelioration 
of the cerebral symptoms, and at the same time lessens 
the irritation of the abdominal viscera. A dose is 
given every ten minutes for an hour, then at less fre- 
quent intervals. Bromides, sulphonal, or chloralamid 
may be used, in addition, to aid in procuring sleep. 

Diarrhoea. — Useful as a temporary expedient in 
diarrhoea occurring as a result of excitement or worry. 
In these cases it may take the place of codeine sul- 
phate ; a dose every hour. 

Dropsy. — Is supposed to be valuable in the neu- 
rotic class of cases as a diuretic, but is of doubtful 
utility. 

Dysmenorrhea. — Generally indicated in those of 
a neurotic type and rather poorly nourished, who are 
more or less subject to neuralgia, indigestion, and fugi- 
tive pains ; a dose is taken every ten minutes for an 
hour, then at less frequent intervals. 

Dysuria. — Is adapted to nervous cases with haema- 
turia; a pill every ten minutes for an hour, then ac- 
cording to the effect produced upon the disease. 

Epilepsy. — Appears to be more particularly indi- 
cated when the disorder is associated with derange- 
ment of the uterine function. In these cases small 
doses should first be tried — a pill every hour ; larger 
doses may be employed later if required. Very large 
doses will be required when the patient has for some 
time been under the influence of opium, alcohol, or 
morphine, as these drugs seem to produce a remarkable 
tolerance for cannabis indica, as much as a drachm of 
the fluid extract being taken with perfect safety. 

Flatulence. — Given in small doses at short inter- 
vals — say, one pill every two hours — it improves di- 



78 THE POCKET PHARMACY. 

gestion and increases the appetite in neurotic patients;, 
it seems to answer the purposes of a carminative. 

Gastralgia. — Is best suited to those of a neurotic 
type, and at the climacteric, alone or with atropine 
when due to ulcer; a dose every two hours. 

Gastric Ulcer. — The same directions apply here 
as when we have to deal with gastralgia. Copper ar- 
senite may be added to the treatment. 

Gastritis. — Adds to the therapeutic effect of cop- 
per arsenite, especially in the chronic gastritis of drunk- 
ards ; a pill is taken every hour, the arsenite being 
dissolved in water and given at the same time. 

Gonorrhoea. — It has a tendency to relieve the pain 
and lessen the discharge, and will prove useful in neu- 
rotic patients; a dose every two hours. 

Hematuria. — Will prove beneficial in albuminu- 
ria; a pill is given every ten minutes for an hour, then 
at less frequent intervals during the day. In the hema- 
turia connected with chronic albuminuria, cannabis 
exercises a favorable influence; and as it has a tran- 
quillizing effect upon the mind, and does not disturb 
digestion like other narcotics, it may occasionally be 
found available when other remedies are contra- 
indicated. A dose is taken every two hours during 
the day. 

Headache. — Useful in the neuralgic headache oc- 
curring in connection with the menstrual period ; a 
pill is dissolved in the mouth every ten minutes for an 
hour. It is very successful in migraine, and in the 
headache due to intestinal indigestion. 

Heart, Dilated. — Is well calculated to allay ex- 
citement in nervous patients ; a dose every hour or two. 

Heart, Hypertrophied. — Along with other treat- 
ment it produces a feeling of comfort and well-being, 



CANNABIS INDICA. 



79 



and will prove acceptable to nervous patients. Gel- 
semium will be found an important auxiliary. 

Hiccough. — Useful as a temporary expedient, on 
account of its influence over the nervous system; a 
dose should be given every ten minutes for one or two 
hours. 

Hypochondriasis. — A very useful remedy in con- 
nection with nervines, haematinics, or hepatic stimu- 
lants as indicated. 

Hysteria. — In certain kinds or varieties of the 
malady hemp is curative; a dose is given hourly for 
several days. 

Impotence. — In small doses, long continued, it has 
a very favorable action ; a dose is taken every three 
hours, alone or in combination with strychnine ar- 
seniate. Both remedies can be combined in the form 
of a tablet or granule. 

Insomnia. — Very useful in the nervous and bilious 
cases, in which it has a favorable action upon the cere- 
brum and upon the nerve-supply of the abdominal vis- 
cera ; a pill is dissolved in the mouth every ten minute? 
for an hour. 

Locomotor Ataxia. — May be of service in over- 
coming the purely nervous symptoms ; a dose every 
two hours. 

Lumbago. — A useful remedy in chronic cases in 
which there are no special indications aside from in- 
testinal indigestion ; a dose every hour, the pill to be 
dissolved in the mouth. 

Melancholia. — Is best suited to the anaemic with 
iron arseniate or strychnine arseniate ; it creates a 
feeling of well-being, and promotes digestion. 

Menorrhagia. — Is of benefit in cases of the neu- 
rotic type, but physiological effects must be avoided ; 



80 THE POCKET PHARMACY. 

a dose every two hours. Creasote, two grains in pill- 
form, three times a day, will prove a valuable addition. 

Nephritis, Acute. — Is of benefit for its diuretic 
properties, and as a nervine ; a dose every ten minutes 
for an hour, then hourly. 

Neuralgia. — Very useful in neurotic patients, with 
bad livers and derangement of the vaso-motor system ; 
a pill is given every ten minutes for an hour or two. 
It is especially indicated for the relief of supra-orbital 
neuralgia and visceral pains. 

Phthisis. — May be used to allay pain and cough, 
but the dose must be gradually increased, or the medi- 
cine discontinued from time to time. 

Puerperal Mania. — Should be given in combina- 
tion with the biniodide when there is a disordered con- 
dition of the digestive apparatus. The addition of ox- 
gall will also be of benefit, providing the stomach will 
tolerate it. 

Seasickness. — Sometimes produces a favorable 
change on the digestive apparatus at the same time 
that it relieves the headache. 

Sleeplessness. — Is often of service when opium 
is contra-indicated ; is of special value when sleepless- 
ness depends upon delayed intestinal digestion, in 
which case it is advisable to add ox-gall or pancreatin 
to the treatment. 

Tetanus. — Sometimes useful — probably in hyster- 
ical cases. It may be given along with chloral or ace- 
tanilide compound in doses sufficient to produce de- 
cided narcotic symptoms. 

Tic-douloureux. — Useful in the neurotic class of 
patients, alone or in combination with aconite or aco- 
nitine ; a dose every ten minutes for an hour or two. 

Trismus. — Of some value for its influence over 



COPPER ARSENITE. 8 r 

the nervous system, but should not be used to produce 
marked physiological effects. 

Typhoid Fever. — Is of service at the times indi- 
cated for the employment of gelsemium, when there is 
much excitement, headache, and more or less delirium, 
and a disordered condition of the digestive apparatus. 
It is also of service later in the disease, during the 
period of convalescence, to buoy up the nervous sys- 
tem and improve the digestion, when it will be advis- 
able to combine it with strychnine arseniate. 



COPPER ARSENITE. 

Each tablet, pill, or granule contains one one-hun- 
dredth grain of the drug. In order to secure good re- 
sults from its administration, thorough trituration with 
sugar of milk is necessary. The tablet of " copper 
arsenite compound," recommended in the following 
pages, has the formula given herewith : 

5 Cupri arsenitis gr. "/„ ; 

Strychninse arsenias gr. */ IOO ; 

Tr. baptisiae, concentrated gtt. j. 

Misce et flat tab. no. j. 
Directions have been given for the employment of 
"solutions" of copper arsenite locally and by inhala- 
tion. These solutions are prepared in the following 
manner : When used in the form of enemata, a single 
tablet containing one grain of the drug is added to a 
pint of boiled water, and to this mixture sufficient di- 
luted hydrochloric acid is added drop by drop to effect 
solution, by which we obtain, in fact, a chlor-arsenite 
of copper solution. For use in the mouth, nares, and 
for vaporization in the treatment of tuberculosis, a 
6 



82 THE POCKET PHARMACY. 

solution is prepared by adding one tablet containing a 
grain to four ounces of boiled water and sufficient di- 
luted hydrochloric acid to make a clear solution ; it 
should be passed through a filter, to remove any sugar 
of milk or arsenious acid which may remain as a sedi- 
ment. 

Experiments made with aceto-arsenite of copper, 
which is more readily soluble than the arsenite, proved 
unsatisfactory, owing to the precipitation of a consid- 
erable portion of arsenious acid, while a solution of 
the chlor-arsenite is stable, showing no indications of 
deterioration after several months. Each thirty min- 
ims of the solution carries approximately x / 6s grain (i 
milligramme), and this amount may be used hypoder- 
matically in the treatment of tubercular affections and 
typhoid fever every second day, without danger of ab- 
scess or any untoward symptoms other than follow the 
use of medicaments in this manner. 

After-pains. — Is a useful remedy in the treatment 
of after-pains when occurring in connection with in- 
testinal fermentation, but should not be depended 
upon when the pains are associated with uterine blood- 
clots. A dose should be given dissolved in a teacup 
of water as hot as can be sipped, the hot water itself 
being a valuable stimulant. 

Alcoholism.— Is used to lessen the irritability of 
the stomach and control the morning vomiting of 
drunkards; a pill is taken dissolved in a teacup of hot 
water half an hour before meals. The addition of 
strychnine arseniate, a dose every two hours, will ma- 
terially lessen the desire for alcohol. 

Anaemia. — Is adapted to the cases marked by dis- 
orders of the alimentary tract, stomachal and intestinal 
fermentation, along with anorexia and constipation. 



COPPER ARSENITE. 83 

Much benefit will be derived from the addition of ipe- 
cac to the treatment ; the copper arsenite should be 
given before and the ipecac after meals, the bowels 
being relieved from time to time by the exhibition of 
salines. 

Aphthae. — The " solution " of copper arsenite is 
used locally and taken internally, as the disease is some- 
times accompanied by diarrhoea, in which case the rem- 
edy is curative, aphthae being often but a symptom of 
intestinal irritation. Regulation of the diet is neces- 
sary, and when the child is nursing it may be advisable 
to add a little artificial aliment. The ulcers should 
be touched with a five-per-cent chromic acid-dextrin 
powder. 

Asthma. — Copper arsenite is an efficacious remedy 
in the treatment of asthma, more especially the au- 
tumnal catarrh, which attacks susceptible persons about 
the time hay-fever makes its appearance — say, the mid- 
dle of August. A tablet dissolved in hot water should 
be given every two or three hours, and the solution 
above described used in the form of a spray at like in- 
tervals, after the employment of peroxide of hydrogen 
(Marchand's) solution to remove accumulated mucus. 
Exposure to atmospheric influences should be avoided 
as far as possible, but when this is not practicable, a 
colorless petrolatum ointment may be applied to the 
nasal mucous membrane. 

Atrophy, Muscular. — Through its influence as a 
"modifier" it ought to prove of service in the various 
forms of muscular atrophy. 

Bed-sores. — May be used in the form of solution 
for bed-sores, being preceded by a solution of hydro- 
gen peroxide, and followed by aristol in the form of a 
powder. 



8 4 THE POCKET PHARMACY. 

Biliousness. — Useful in the early stages of those 
cases marked by fermentation of food, indigestion, at- 
tacks of dizziness with colicky pains, associated with 
diarrhoea and constipation in alternation. Copper ar- 
senite is almost a specific; one pill dissolved in hot 
water should be taken half an hour before eating, and 
the diet properly regulated. Children five years of 
age and upward take one pill daily in divided doses; 
or a granule containing one one-thousandth of a grain 
may be given at intervals of two hours. 

Blepharitis. — Should be used locally in the form 
of a solution, and followed by purified petrolatum con- 
taining a percentage of paraffin. 

Bone, Disease of. — Copper arsenite is of signal 
benefit in improving nutrition in diseases of bones, 
along with Hewson's clay dressing, to arrest local in- 
flammation. 

Breath, Fetid. — One pill is dissolved in hot water, 
four to six ounces, and taken at once as hot as can be 
borne. Fetor due to fermentation and decomposition 
of food is promptly arrested. 

Cachexia. — Is especially useful in those forms of 
cachexia following prolonged illness, often dependent 
on the condition of the alimentary tract. The tablet 
known as "copper arsenite compound," given in hot 
water before meals, is efficient along with regulated 
diet. 

Cancrum Oris.— Should be given in the form of a 
solution, or just before taking food ; a child four weeks 
of age can take one one-thousandth of a grain three or 
four times a day. 

Catarrh, Acute Nasal.— Used in the form of a 
solution as a spray, three or four times a day, along 
with quinine, to be followed by calcium sulphide. This 



COPPER ARSENITE. 85 

treatment is especially useful in autumnal catarrh or 
hay-fever, with profuse watery secretions and sneez- 
ing, in which case it is best to add to the local treat- 
ment the internal use of gelsemium. 

Catarrh, Chronic Nasal. — In the beginning it is 
often satisfactory to employ the remedy in the form 
of a spray, after using the peroxide, as in acute cases, 
with quinine. After a few days the choice for internal 
medication will lie between calcium sulphide and ar- 
senic sulphide, although, if the pulse is rapid and secre- 
tion profuse, gelsemium will be indicated. 

Chlorosis. — In connection with the remarks cover- 
ing the employment of iron arseniate in this disorder, 
when the digestive organs do not respond, owing per- 
haps to the vitiated character of the secretions, over- 
production of mucus with fermentation of food, the 
copper arsenite should be substituted for the iron 
preparation. A pill should be taken dissolved in hot 
water half an hour before meals and at bed-hour. The 
compound tablets will often be found preferable to the 
single remedy, on account of the contained strychnine 
and small amount of baptisia. 

Cholera, Asiatic. — Might be expected to produce 
a favorable effect upon the vomiting as well as upon 
the pathological changes occurring in the intestinal 
tract. It should be given in small doses by the mouth, 
say, one one-thousandth of a grain every hour, and 
larger quantities by enemata, say, one fourth of a 
grain in solution ; a pint of water every three hours. 

Cholera Infantum. — With attention to diet and 
hygiene, arsenite of copper is a superior remedy in this 
disease. In extremely bad cases a pill should be dis- 
solved in four ounces of boiled water, to which a tea- 
spoonful of good whiskey is added, and the child given 



86 THE POCKET PHARMACY. 

ten drops every ten minutes for an hour. As the dose 
is so very small, and as some physicians seem to think 
that water is at times contra-indicated, a tablet con- 
taining the exact dose can be prepared, or a teaspoon- 
ful of the foregoing solution can be added to food 
every two or three hours. Where the indications point 
to the lower bowel as a favorable point for the absorp- 
tion of poisons, an ounce of the solution should be 
added to a pint of warm water and the colon flushed 
with this several times during the day. 

Cholera Morbus. — In the serious cases, as they 
occur in adults, a pill in hot water is taken every two 
or three hours, along with gelsemium, to reduce the 
pulse and fever. Morphine may occasionally be de- 
manded to quiet paroxysmal pains, although either co- 
deine sulphate or bryonia are well calculated to take 
its place. Where a saline is given under domestic 
management, the physician may find the patient suffer- 
ing from an irritative colitis, in which case an enema 
of the copper arsenite solution should be given at 
once, as no benefit can be expected from the employ- 
ment of opiates in these cases. 

As bearing upon the physiological actions of copper 
arsenite, from which therapeutic deductions are war- 
ranted, it may be mentioned here that cases of poison- 
ing from Paris green have been reported which enable 
us to calculate with some degree of accuracy the ther- 
apy of copper arsenite, Paris green being simply the 
aceto-arsenite of copper. Upon entering the stomach, 
copper arsenite is changed into chlor-arsenite by the 
action of the hydrochloric acid of the gastric juice. 
In the absence of the latter, failure may result, as the 
drug is ordinarily insoluble. Post-mortem appearances 
show that the poison — aceto-arsenite of copper — has a 



COPPER ARSENITE. 87 

special tendency to affect the stomach and small intes- 
tine, especially the solitary glands, Peyer's patches, 
and the mucous membrane in the immediate vicinity of 
the caecum. Lethal doses produce marked vascularity 
of the mucous membrane lining the stomach and small 
intestine, even to the extent of erosion, although this 
latter condition is somewhat irregular. There is a 
flabby condition of the liver, with some evidences of 
organic changes in both parenchyma and lobules, along 
with more or less congestion. The kidneys are also 
congested, haemorrhages being observed, and like 
changes are noticeable in the mucous membranes of 
the ureters and bladder. Similar changes are also 
found in the cardiac muscle, but the lungs and pleurae 
♦do not appear to suffer in acute cases. The evidence 
is clear that the drug is of value as a remedial agent 
through its stimulant (irritant) action upon the epi- 
thelial cells, either direct or through the medium of 
the nervous system, which seems to furnish substantial 
proof that cellular therapy is not altogether an im- 
probable hypothesis. 

Chorea. — Useful for its well-known influence upon 
the nervous system and upon digestion. A pill can be 
given every three hours to a child five years of age. 

Colic, Intestinal.— For adults, a single pill is dis- 
solved in water as hot as can be borne, and taken at 
once ; bryonia may be added when especially indicated. 

Colic, Lead. — Inasmuch as lead colic is mani- 
fested by contraction of the abdominal muscles, and 
that from copper by distention, it may be that suffi- 
cient dosage of copper would overcome it; but this 
has not been tested. 

Constipation. — Useful when due to indigestion or 
retarded digestion with fermentation of food and flatu- 



88 THE POCKET PHARMACY. 

lence ; either the arsenite alone, or the compound ar- 
senite tablet, should be taken before meals. It is ad- 
visable to alternate with creasote, using a saline as 
required. 

Convalescence. — Applicable in those cases char- 
acterized by profound depression, in connection with 
nourishing and readily digestible food. It may be 
given in the form of arsenite compound, in hot water, 
half an hour before meals. The strychnine overcomes 
the exhaustion and thereby promotes sleep, thus pre- 
cluding the necessity for hypnotics, of which chlorala- 
mid appears to be the most suitable during recovery 
from protracted illness. As intestinal indigestion is 
most prominent after typhoid fever, it may be found 
advisable to administer the medicine between meals as 
well as before eating. 

Croup. — Is recommended in the catarrhal variety 
in the form of a spray or vapor, which can be readily 
accomplished by the addition to solution of a quantity 
of glycerin, about equal parts. This can be employed 
at intervals of half an hour, in addition to internal 
medication. 

Debility. — In debility from any cause, it is used as 
a stimulant to the digestive apparatus and the nervous 
system ; a pill is taken in hot water at intervals of four 
hours, with appropriate diet. 

Delirium Tremens. — Adapted to the bilious cases 
with furred tongue and obstinate vomiting. A single 
pill is dissolved in a cup of hot water or hot capsicum 
tea, and taken at once ; this should be followed by the 
internal use of cannabis indica and strychnine arseni- 
ate as indicated. The judicious employment of this 
plan may obviate the necessity for nutritive enemata. 

Dentition. — Is used here to correct the bowel 



COPPER ARSENITE. 



8 9 



troubles. The general condition of the system requires 
attention ; assimilation may be defective, or bone-mak- 
ing material wanting. Phosphoric acid or phosphorus 
may be demanded. 

Diarrhoea. — Current medical literature during the 
past two years has contained reports of large numbers 
of cases in which copper arsenite has been successfully 
used in the treatment of diarrhoea and allied disor- 
ders. My report to the Medical Society of the State 
of Pennsylvania, June, 1890, covering six hundred and 
ninety-four cases treated by this remedy, included one 
hundred and ninety-eight cases of diarrhoea and dys- 
entery from nineteen observers. I published also frag- 
mentary reports from twenty-six observers in the Med- 
ical News, November 9, 1889, in which this remedy 
had been employed for the relief of bowel affections 
with most marked success. In a very large majority 
of the cases to which it is adapted the effect is prompt 
and relief permanent ; moreover, there is seldom any 
distinct demand for either preliminary or after-treat- 
ment, the remedy itself being all-sufficient to change the 
phase of the morbid complexus. My views in regard to 
its physiological action have been published in a paper 
contributed to the Edinburgh Medical Journal for 
November, 1890, by my friend Dr. J. L. Porteous, of 
Yonkers, New York, and cover essentially the views 
which I now hold in relation to its influence upon cell 
activity. 

At first I was not disposed to esteem copper arse- 
nite a remedy of great value in chronic cases, nor even 
in the subacute variety of bowel affections, but a larger 
and more varied experience, both North and South, 
warrants the statement that comparatively few cases 
of bowel affections will be seen in private practice 



9 o 



THE POCKET PHARMACY. 



which are not amenable to its therapeutic application. 
Occasionally it will be found that both diarrhoea and 
dysentery will be followed by a colitis, more or less 
troublesome, in which mucus and watery discharges 
pass from the bowels involuntarily. This condition 
requires both local and constitutional measures ; the 
local treatment will consist in flushing the colon with 
a solution of copper arsenite, as described above — one 
grain to the pint of boiled water. In these cases it is 
advisable to substitute for the copper arsenite the bin- 
iodide — a dose dissolved in a cup of water three times 
a day. Dysentery is for the most part a self-perpetu- 
ating disease, and will respond promptly to appropriate 
local treatment ; but when we admit, as well we may, 
that the causation may be intimately related to a tor- 
pid condition of the liver, local measures will only be 
of temporary benefit. It is in this class of affections 
that large doses of calomel and emetic doses of ipecac 
are so highly prized, but neither of the remedies men- 
tioned will accomplish more than the small doses of 
the biniodide suggested, and therefore, for the comfort 
of the patient, its virtues should be studied clinically. 

Diarrhoea of Phthisis.— A pill should be given in 
hot water half an hour before meals. 

Diarrhoea of Typhoid.— A pill is given daily dis- 
solved in boiled water, and distributed over the entire 
day in hourly doses, except when the patient is asleep. 
A point should be made to give a dose of the medicine 
before taking food. The faithful employment of this 
remedy in typhoid along with symptomatic medication 
maintains a comparatively low temperature, avoids 
complications, and leaves the patient at the end of the 
disease with an excellent condition of the digestive 
apparatus. 



COPPER ARSENITE. g r 

Diphtheria. — May be used in the early stages 
when atropine is indicated ; the antiseptic properties 
would lead to the belief that it might be of service in 
this most fatal disease if brought into direct contact 
with the diseased tissues. A pill can be dissolved in 
the mouth every two hours, together with the frequent 
use of a spray or vapor, using for the purpose the solu- 
tion mentioned. 

Dyspepsia. — A pill given in hot water half an 
hour before meals will promptly arrest fermentation 
and correct an unhealthy condition of the mucous 
structures. 

Eczema. — Useful as an aid to the digestive func- 
tions in improving the nutrition. A pill is given before 
eating, with or without hot water, depending upon the 
condition of the mucous membranes. When there is 
an increased secretion of mucus, the hot water is indi- 
cated for the purpose of thoroughly distributing the 
medicament. In addition, it will be advisable to have 
the patient use an alkaline solution locally once or 
twice daily in those cases in which water is not contra- 
indicated. 

Enteritis. — Along with the exhibition of vascular 
sedatives, aconite and gelsemium, it should be em- 
ployed much the same as in typhoid fever, with mor- 
phine, codeine, or bryonia to subdue the pain. In the 
subacute and chronic cases it may be advisable to ex- 
hibit castor-oil, and after the bowels have been moved 
an enema of copper-arsenite solution can be given — 
one grain to the pint as directed. This remedy might 
be used also in the treatment of membranous enteritis, 
along with calcium sulphide and the biniodide, with 
reasonable hopes of success. 

Epilepsy. — Is often of benefit in restoring the di- 



g 2 THE POCKET PHARMACY. 

gestive organs to a healthy condition ; a pill in hot 
water half an hour before meals. 

Erythema. — Useful to correct gastro-intestinal 
disorders, upon which it not infrequently depends, but 
the diet must be regulated. Aristol is a suitable local 
application. 

Gastralgia. — Often affords immediate relief ; a pill 
is taken in hot water half an hour before eating, and 
the diet regulated. Cannabis indica is added to the 
treatment in neurotic cases, and rhus toxicodendron in 
those having a rheumatic history. As many of these 
patients present lithaemic symptoms, the urine should 
first be examined ; in case the diagnosis is confirmed, 
lithium bromide in combination with liquor potassium 
citrate should be given between meals. 

Gastric Ulcer. — The remedy is used in the same 
manner as when treating gastralgia. 

Gastritis. — Copper arsenite has what may be 
termed a soothing effect upon mucous membranes 
when given in small doses, and with proper attention 
to diet is curative in this disease. Small doses are 
best suited to the acute cases ; a pill is dissolved in 
water and distributed over the entire day in hourly 
doses. 

Glanders. — Should be given internally and used 
locally in the strength of one grain to four ounces of 
water, after thorough disinfection with the peroxide of 
hydrogen (Marchand's). 

Gleet. — Is used in the form of a solution, one grain 
to four ounces of boiled water, sufficient diluted hydro- 
chloric acid being added to make a clear solution. The 
injection should be used three or four times a day, an 
equal quantity of hot water being added to lessen irri- 
tation. In chronic cases the peroxide should first be 



COPPER ARSENITE. 



93 



used to remove any unhealthy secretion which may be 
present. Gleet due to stricture requires surgical at- 
tention. 

Glossitis. — Useful when due to stomach derange- 
ment. In case the tongue is swollen, so that the rem- 
edy can not be readily taken, the solution can be in- 
troduced into the buccal cavity by means of the spray. 
When glossitis appears as a complication of salivation, 
a weak solution of nitric acid should be employed. 

Glottis, CEdema of. — Probably no remedy pro- 
duces a more prompt and favorable action upon the 
throat structures than copper arsenite in solution. In 
oedema of the glottis, the spray and vapor should be 
employed as in the treatment of croup and diphtheria. 

Gonorrhoea. — May be used in the form of a solu- 
tion, as suggested in the treatment of gleet. It lessens 
the irritability of the urethra, and shortens the period 
of the disease. 

Gums, Spongy. — Is indicated to meet the debility 
of which this is merely a symptom ; a pill is given in 
hot water half an hour before meals, and the solution 
used as a mouth-wash. 

Hay-fever. — Used locally in the form of a solu- 
tion, as suggested in the treatment of nasal catarrh. 
The patient should avoid, as far as possible, atmospheric 
influences, and as soon as the active symptoms have 
subsided quinine in substantial doses is indicated. The 
preliminary use of the peroxide will materially expe- 
dite treatment. 

Headache. — Generally efficient when the pain is 
directly or indirectly due to indigestion or slow diges- 
tion. A pill is dissolved in hot water and taken at 
once, hot as can be sipped ; this may be repeated in an 
hour or two if the headache has not disappeared. 



g4 THE POCKET PHARMACY. 

Heartburn. — Should be taken in solution with hot 
water ; a pill is dissolved in four ounces of water and 
sipped in the course of a few minutes. 

Influenza. — Used locally as a spray and vapor in 
solution, and given internally for its effect upon the 
digestive apparatus and the nervous system. It is 
especially adapted to those cases in which the bowels 
appear to suffer the brunt of the disease. 

Intertrigo. — Used locally in the form of the solu- 
tion ; the parts should be dressed several times a day, 
and boric acid or aristoi used as a dusting powder. 

Leucorrhoea. — Is used in the form of a hot douche, 
one grain to a quart of water, at bed-hour. The pre- 
liminary use of the peroxide solution will be found 
beneficial. 

Nausea. — Useful in nearly all forms of nausea, ex- 
cept, perhaps, that dependent upon cirrhosis of the liver. 
It is a very efficient remedy even in the most threatening 
cases ; a pill is taken at once with or without hot water, 
according to the indications present. 

Nightmare. — When due to intestinal indigestion, 
a pill is taken in hot water on retiring. 

Nipples, Sore. — Used in the form of a solution, 
and followed by a dusting powder of boric acid or 
aristoi. 

Peritonitis. — Should be employed by the stomach 
and by enemata to arrest septic influences and over- 
come tympanites. 

Phthisis. — Should be inhaled in the form of a 
vapor several times daily, using the solution already 
described, and administering creasote internally. It 
may also be used hypodermatically ; thirty minims of 
the solution, carrying one milligramme of the medicine, 
can be injected under the skin between the scapulae 



COPPER ARSENITE. 95 

every day, or every other day, with the best results in 
tuberculosis. In addition to the beneficial action it 
has upon the temperature and digestion, it is also of 
service in arresting the night-sweats. 

Prolapsus Ani. — An excellent remedy in recent 
cases, used in the form of an enema with hot water, 
one grain to the pint. 

Puerperal Fever. — May be used to arrest the 
tympanites and relieve pain after the exhibition of 
salines. 

Pyrosis. — Very prompt in its action ; in severe 
cases it should be taken in hot water, and an effort 
made to remove the cause. Creasote or nitro-hydro- 
chloric acid should be taken before meals, or large 
doses of sodium bicarbonate about two hours after 
meals. 

Scarlet Fever. — May be used in the early stages 
to check vomiting, and later on, when the tongue is 
red, to improve the condition of the digestive appara- 
tus. It may also be used in the form of a spray to the 
throat for its antiseptic action. 

Scurvy. — Indicated to correct stomatitis and sali- 
vation ; it is preferably given in the form of a solution, 
two or three pills daily, in hourly doses, along with a 
weak solution as a gargle. 

Seasickness. — A very successful remedy, provid- 
ing the patient is not suffering from constipation or a 
bad condition of the liver, both of which may be re- 
lieved temporarily by a saline the day before sailing. 
A dose is taken half an hour before meals. 

Sneezing. — When occurring in connection with 
hay-asthma, should be used in the form of a solution 
by means of a spray ; and care must be exercised in 
order that the solution may come into contact with as 



o6 the pocket pharmacy. 

large a portion of the nasal mucous membrane as pos- 
sible. 

Stomatitis. — Should be given internally and used 
locally in the strength of the solution recommended. 
Creasote is sometimes a valuable adjunct to the treat- 
ment, or it may be alternated with hydrochloric acid. 

Strophulus. — Useful to correct the condition of 
the stomach ; an inquiry should be made in regard to 
the food supply of children thus affected. 

Syphilis. — Is employed to correct any digestive 
disturbances incident to medication. Whether it will 
have any eliminative action upon the poison remains 
to be determined. 

Tonsillitis. — Is of value in subacute cases, where 
enlargement of the tonsils is frequently due to digest- 
ive disturbances. It may also be used in the form of 
a spray or gargle in weak solution, as it exercises a 
salutary effect upon relaxed and inflamed tissues. An 
important point to be borne in mind is the correction 
of the dietary, which is often an exciting cause. 

Tympanites. — Useful in those cases occurring 
from decomposition of food or chemical changes in 
the intestine. It maybe alternated with terebene or 
turpentine, but salines must be used cautiously in ty- 
phoid fever. Enemata may be used in the latter dis- 
ease ; much may be gained in " walking" cases by 
regulation of the diet. 

Typhoid Fever.— Will produce a favorable change 
in the disease given at any period, with the exception, 
of course, of complications, such as intestinal perfora- 
tion and haemorrhage, hypostatic pneumonia, etc. ; one 
pill in solution is given daily in divided hourly doses. 
Not infrequently the compound pill will be more bene- 
ficial than the arsenite alone. Its continued use in 



COPPER ARSENITE. 97 

small doses enables us to maintain a moderately low 
temperature, a good pulse-rate, comparative freedom 
from great abdominal pain and tympanites, and lessens 
materially the number of stools, while it greatly im- 
proves their character and consistency. The detergent 
properties of copper arsenite must be something re- 
markable, as scabs have been observed in the faeces, 
supposed to have been torn from intestinal ulcers, 
without a single blood-streak showing in the stools. 
There is, however, in typhoid fever one condition which 
this remedy fails to relieve, and when present to any 
marked extent it is far less useful than under other 
conditions. Reference is here made to hepatitis : 
when the system is surcharged with the poison, the 
brunt of which comes upon the liver, and the organ 
becomes disabled, indicated by vomiting, frequent 
watery, bad-smelling stools, arsenite of copper must 
be replaced by the biniodide. It is of but little value 
for the relief of these symptoms, for they are nothing 
more. As it occurs in this section of the country, ty- 
phoid fever, in most instances, can be conducted to a 
successful termination by the continued employment 
of this remedy as the principal treatment. Complica- 
tions which may arise can not be referred to here, ex- 
cept to say that under this plan they rarely occur, but 
when present will require symptomatic treatment. 

Vomiting'. — As it occurs from gastro-intestinal 
disturbance, when the tongue is rather freely coated, a 
pill may be taken at once in a teacup of hot water ; 
when not immediately arrested, large draughts of hot 
water, with sodium bicarbonate if deemed best, should 
be drunk, thus allowing the contents of the stomach 
to be freely discharged, after which a second pill may 
be taken in the same manner as the first. The patient 
1 



9 8 



THE POCKET PHARMACY. 



should then be instructed to lie on the right side in- 
stead of on the left, as would be indicated in the case 
of flatulency. 

Yellow Fever. — It seems as though this combina- 
tion would be a valuable remedy ; it could be given 
internally, and would thus assist in correcting the dis- 
ordered condition of the stomach. In addition to in- 
ternal medication, flushing the colon with a weak solu- 
tion, a grain to the pint, at intervals of an hour or 
two, would assist materially in preventing the absorp- 
tion of poisonous products. On the appearance of pro- 
nounced jaundice the indications would point to the in- 
ternal use of the biniodide in the manner just described. 
Gibier has made favorable reports of the efficacy of 
salol in this disease, in the belief that the beneficial 
effects are dependent upon intestinal antisepsis. Five 
grains should be given in the form of wafers or soft 
capsules every two hours, the urine to be examined 
from time to time in order to avoid the toxic effects 
of any carbolic acid which may be set free. This treat- 
ment, however, need not interfere with the employ- 
ment of copper arsenite as outlined. The investiga- 
tions of Lowenthal in regard to the therapeutic value 
of salol in cholera would also indicate its use in yellow 
fever. 

GELSEMIUM. 

Each tablet, pill, or granule contains one half minim 
of the fluid extract prepared from an assayed product. 
Recent observations lead to the belief that gelsemin, in 
doses of one sixty-fourth of a grain, may be used in- 
stead of the fluid extract. 

After-pains. — Should be used only when the pulse 



GELSEMIUM. QQ 

is rapid, with indications of local congestions and other 
derangements of the circulation. Pains of this char- 
acter may be due to the injudicious employment of 
ergot, in which case gelsemium is indicated. It must 
be used with caution, owing to its tendency to retard 
involution through depression, when administered in 
sufficient dosage to produce physiological effects; 
under these circumstances it may even favor second- 
ary haemorrhage. A dose may be given at intervals of 
an hour for several hours in succession. 

Asthma. — Is of temporary benefit in asthma when 
shortness of breath is due to increased activity of the 
circulation. It seems to have the effect of lessening 
the demands of the respiratory apparatus, and may 
with benefit be combined with arsenic in small doses. 

Bubo. — Useful in the early stage to reduce tem- 
perature and quiet the circulation ; a dose may be 
taken every hour or two. 

Catarrh, Acute Nasal. — Whoever has studied 
the subjective sensations produced by powerful car- 
diac contractions while in the recumbent posture, will 
readily perceive the philosophy of employing gelse- 
mium in acute nasal catarrh with profuse secretions. 
In this disorder it is far superior to aconite ; a dose 
should be given every hour or two for a day, then at 
less frequent intervals, the parts being kept free from 
accumulations of mucus by appropriate local medica- 
tion. 

Cerebral Anaemia. — In the active variety, due to 
increased arterial tension, this remedy seems to modify 
the effect produced by trinitrin, and gives better re- 
sults than when the latter is used alone. It is best 
adapted to the sthenic cases — a dose every hour or 
two, dissolved in the mouth. 

f LoFC. 



I00 THE POCKET PHARMACY. 

Cerebral Congestion. — One of our most efficient 
remedies, indicated when there is great motor excite- 
ment, even spasm. It is very efficacious in acute alco- 
holism, but must be given with caution to old drunk- 
ards. Local bloodletting should be practiced when 
the desired effect can not be readily produced by the 
drug. 

Chordee. — A most useful remedy, either alone or 
with cannabis indica or strychnine arseniate, accord- 
ing to the indications. It allays peripheral irritation 
of this character better than atropine. A dose is given 
every ten minutes for an hour, or the medicine can be 
distributed throughout the entire day, a dose every 
two hours when it does not cause too much depression. 

Chorea. — Favors sleep, and may often prove use- 
ful in maintaining the normal secretions, when ad- 
ministering frequently repeated doses of iron arseni- 
ate ; a dose every hour or two. 

Choroiditis. — Used to reduce intra-ocular press- 
ure by lessening the activity of the circulation ; a dose 
may be given every two or three hours. 

Convulsions. — An efficient remedy to reduce ar- 
terial tension, alone or in combination with acetaniiide 
compound, to relieve any irritation which may act as 
the exciting cause. Warm baths are indicated ; a dose 
is given every ten minutes for an hour, and the effect 
upon the patient studied. 

Cough. — A useful remedy for spasmodic, nervous 
cough, and for the cough of habit ; a pill should be 
dissolved in the mouth every two or three hours, alone 
or in combination with bryonia, when pain attends. 
In connection with this, it should be mentioned that 
many chronic cases are promptly benefited by the ad- 
dition of terpin hydrate, or terebene, when there is 



GELSEMIUM. IO i 

much expectoration of mucus. In the absence of 
mucus, cod-liver oil and pilocarpine hydrochlorate, 
one fiftieth of a grain, should be added to the treat- 
ment. The former is given a teaspoonful an hour 
after meals, and the latter at the same time as the 
gelsemium. 

Delirium Tremens. — Must be used with caution, 
and protected by strychnine arseniate when given to 
reduce the pulse-rate and arterial tension. It lessens 
the activity of the circulation in the acute stage and 
favors sleep, but must be used with discrimination in 
old drunkards. The addition of cannabis indica is 
often of benefit. 

Dysmenorrhea. — Used in the congestive form, 
in sthenic cases, alone or with aconite, when the pulse 
is rapid and there is great motor excitement ; a decided 
improvement will be noticeable from the exhibition of 
a dose every ten minutes for an hour. 

Dysuria. — Will often afford prompt relief when 
there is high arterial tension ; a dose is given every 
ten minutes for an hour, and when due to cold and 
exposure this should be followed by substantial doses 
of quinine hydrochlorate. 

Earache. — Adapted to the catarrhal cases occur- 
ring after cold and exposure, to reduce fever and pulse- 
rate ; it should be given along with calcium sulphide, 
to prevent the formation of pus; a dose every hour, 
but no poultices. Baunscheidtismus may be practiced 
over the mastoid cells. 

Enteritis. — Is given either alone or with aconite 
in the acute cases. A dose is taken every hour, proper 
attention being given to feeding ; food stuffs digested 
principally in the stomach are to be allowed. 

Epistaxis. — May be used instead of aconite, but 



I0 2 THE POCKET PHARMACY. 

in flabby patients ergot must be added to the treat- 
ment. 

Exophthalmus. — Indicated to reduce the pulse- 
rate ; a dose every three hours. Ergot in the solid 
form is useful in connection with gelsemium, but nu- 
trition is of the greatest importance. 

Fever. — Used to reduce the activity of the circu- 
lation in sthenic fevers and malarious conditions, like 
aconite. It is employed also in connection with bry- 
onia in the treatment of pneumonia and pleurisy ; a 
dose every half-hour at first, then at intervals of an 
hour until the desired effect is secured. 

Gonorrhoea. — Employed to lessen the pulse-rate 
and reduce tension in the acute stage ; a dose every 
two or three hours. 

Haemoptysis. — Lowers the general circulation, 
although it has no curative action. Ergot or hama- 
melis should be given as soon as possible. 

Headache. — Especially adapted to those cases 
characterized by a sense of fullness in the head, with 
rapid pulse ; a dose is taken every half-hour for sev- 
eral hours. It should be added to the treatment of 
those obstinate cases in which cannabis is indicated. 

Heart, Hypertrophied.— Useful in those cases 
where there is general increased arterial tension, indi- 
cated by the character of the pulse in the extremities; 
a dose every three or four hours daily. 

Hectic. — May be used cautiously to lessen the 
pulse-rate and to favor the action of quinine; a dose 
is taken every hour or oftener for several hours, to be 
followed by quinine. 

Inflammation. — Is given alone or in combination 
with aconite, not more than ten pills daily as a rule, 
although there will be found exceptions; a dose may 



GELSEMIUM. 



103 



be given every fifteen minutes for an hour, then at in- 
tervals of an hour. 

Influenza. — Used to reduce pulse-rate and fever 
only in the early stages. It lessens arterial tension 
and improves the condition of the digestive apparatus; 
a dose is taken every ten minutes for an hour, then in 
hourly doses, followed by appropriate medication. 

Insomnia. — Adapted to the cases in which there 
is high arterial tension with throbbing temples ; a pill 
is dissolved in the mouth every fifteen minutes, until 
two or three have been taken just before retiring. 

Intermittent Fever. — Is given alone or with aco- 
nite as a preliminary to the exhibition of quinine ; a 
dose of each is given every ten or fifteen minutes for an 
hour or two, according to the effect produced, the pa- 
tient to maintain the recumbent posture. The object of 
this treatment, it will be apparent, is to secure a favor- 
able condition of the secretions by lessening the ar- 
terial tension and reducing temperature. This plan of 
treatment favors the discharge of heat, but has no in- 
fluence upon heat-formation. 

Mania. — Used to quiet motor excitement and re- 
duce arterial tension ; a dose may be given every hour, 
alone or in combination with cannabis. 

Measles. — Is given alone or in combination with 
aconite, to reduce fever and excitement, and favor the 
action of the skin ; a dose is given every hour or two 
during the forenoon, and followed by suitable doses of 
quinine. 

Melancholia. — Adapted to the cases with high ar- 
terial tension ; a dose is taken three times a day, alone 
or with cannabis indica. 

Meniere's Disease. — Will best suit the sthenic 
cases ; a dose every four hours. 



I0 4 THE POCKET PHARMACY. 

Meningitis, Cerebral.— Is given along with aco- 
nite to reduce the activity of the circulation; a dose 
hourly for several hours. 

Metritis. — Useful in the acute stage along with 
aconite ; salines are indicated previous to the exhibi- 
tion of quinine and the salicylates. 

Myalgia. — Is beneficial, but very large doses are 
necessary — so large, in fact, that they seem unsafe, when 
ten drops distributed over as many hours will gener- 
ally produce double vision, and occasionally ptosis. 

Nervousness. — An excellent remedy to allay sim- 
ple excitement and promote sleep ; several doses, half 
an hour apart, can be taken before retiring. 

Neuralgia. — Is adapted to the same class of cases 
as aconite, but in moderate doses produces a more 
general effect, and affords relief for a longer period; 
a dose is taken every half-hour for several hours, fol- 
lowed by appropriate treatment for the removal of the 
cause. 

Paronychia. — Useful to reduce the pulse when 
treatment is begun before the formation of pus ; the 
latter always demands surgical aid. 

Pertussis. — Very useful in reducing the pulse-rate 
and in overcoming the spasm ; it is of much benefit 
when treatment by quinine is adopted, as it has a ten- 
dency to relieve the head symptoms following the ex- 
hibition of large doses. A dose may be given every 
three hours to a child five years of age. Drosera is 
said to be especially useful in connection with the qui- 
nine treatment 

Phthisis. — May be employed to reduce the pulse- 
rate when new sections of the lung-structure are in- 
vaded, and should be followed by the exhibition of 
quinine. 



GELSEMIUM. 



105 



Pleurisy. — Seems to be even more useful in sthenic 
cases than aconite, and may be given along with bry- 
onia with much benefit ; a dose of each every half-hour 
at first, then at hourly intervals. 

Pneumonia. — Used in the early stages to improve 
the character and frequency of the pulse ; when that 
becomes soft and compressible, accompanied by free 
perspiration, it should be followed by quinine in sub- 
stantial dosage. 

Scarlet Fever. — May be used in the early stage 
of the disease to reduce the pulse-rate and temperature, 
but caution is necessary when acetanilide compound is 
given at the same time. 

Sleeplessness. — Applicable when the arterial ten- 
sion is high ; several doses are taken at intervals of 
half an hour before retiring. 

Sneezing. — May be used in connection with cop- 
per arsenite in solution, to diminish secretion and arrest 
the formation of profuse quantities of mucus; a dose 
is given every half-hour for several hours. 

Spinal Congestion. — Indicated to reduce arterial 
tension, but in these instances much can be gained by 
the judicious use of salines followed by ergot. 

Sunstroke. — Should be given only in heat-fever, 
along with antipyrine, twenty to thirty grains by enema, 
to reduce temperature. Ice and cold delay the action 
of antipyrine, and must be avoided. 

Tetanus. — Has proved an efficient remedy for the 
control of spasm, but the suggestion is put forward 
that biniodide should be added to the treatment. This 
recommendation is based on the fact that the tetanus 
poison is deposited in the liver, and the biniodide act- 
ing energetically upon the cells of this viscus, and pos- 
sessing besides powerful antiseptic properties, would 



io 6 THE POCKET PHARMACY. 

favor both the destruction and elimination of the 
poison. 

Tic-douloureux. — Indicated to relieve high ar- 
terial tension, and when suitable medication accom- 
panies its use, this remedy is practically curative. 

Tonsillitis. — Should be given along with aconite 
when there is high motor excitement or delirium; a 
dose every half-hour for several hours. 

Toothache. — Relieves those cases occasionally 
which are due to caries, and are set up from time to 
time by exposure to cold. 

Trismus. — This remedy alone, or in combination 
with coniuirij should be used in connection with the 
biniodide and salines to remove any offending ma- 
terial in the alimentary canal when occurring in chil- 
dren 

Typhoid Fever. — Is cautiously employed when 
the secretions are arrested, the tongue and skin dry, 
and the patient asking constantly for water. This 
remedy, by lowering vascular tension, very quickly 
produces a marked change for the better. 

Yellow Fever. — May be used in the early stages 
to correct disturbances in the vascular tension, and to 
favor the restoration of the normal secretions. 



IPECAC. 

Each tablet, pill, or granule contains one-f our th grain 
of the drug. Recent observations lead to the belief 
that emetine, the active principle, in doses of one milli- 
gramme (gr. y 6s ), may take the place of the crude drug, 
although this has not been fully determined upon. 

Acidity of the Stomach. — Ipecac is useful in 



IPECAC. 



107 



acidity of the stomach due to a lack of peptic ferment, 
and accompanied by fermentation ; it is also of value 
when we have to deal with stomach derangement due 
to a torpid condition of the liver, ipecac being an active 
hepatic stimulant. In pregnancy, it should be com- 
bined with strychnine arseniate ; a dose of each after 
meals and midway between meals. 

Anaemia. — Is one of our most efficient hepatic 
stimulants when the anaemia is of recent origin, and 
should be employed as a preliminary to the adminis- 
tration of iron. It can be given in combination with 
strychnine arseniate in the same manner as indicated 
in acidity of the stomach. The addition of strychnine 
arseniate is of material assistance in overcoming vaso- 
motor derangements. 

Asthma, Bronchial. — Ipecac is given internally, 
and the wine used as a spray in bronchial asthma in 
both adults and children, but is probably of more value 
in the latter ; a pill is given every three hours to a 
child five years of age. It is indirectly valuable in 
true asthma through its action upon the liver, but 
emesis should be avoided. This can be accomplished 
by withholding water about the time the medicine is 
exhibited. 

Bronchitis, Acute and Chronic— Is indicated 
in subacute and chronic cases in which the liver is im- 
plicated, with more or less indigestion ; the expectora- 
tion is thick, tenacious, and yellowish-green, but does 
not come up readily. Physical examination but con- 
firms the objective signs ; dry and moist rales are found 
both anteriorly and posteriorly. Prompt benefit will 
follow the employment of ipecac, one pill after meals 
and one midway between meals and at bed-hour. No 
benefit is derived from its exhibition in emetic doses, 



108 THE POCKET PHARMACY. 

if we count the cost to the patient in the way of strain 
and derangement of the digestive apparatus. 

Cerebral Anaemia.— A useful remedy in that form 
of venous stasis which simulates cerebral anaemia ; it 
is, in fact, a form of passive congestion, and should be 
so regarded. A dose is given every three hours. 

Cholera, Asiatic. — In cases where the condition 
of the stomach will permit, ipecac— a dose every three 
hours — might be of service in stimulating the function 
of the liver, although the biniodide would be the pref- 
erable remedy. 

Constipation. — Useful in the so-called bilious 
cases. Hot water should be taken before breakfast, 
with a pill after meals and between meals, along with 
an occasional dose of cascara sagrada or a saline. 

Cough. — Is useful in the variety known as bilious 
cough, in which the alterative pill is recommended as 
a preliminary ; a pill is taken after meals and between 
meals, together with the local use of the spray of the 
wine or of the peroxide of hydrogen. For strumous 
patients it is advisable to add cod-liver oil, or cod-liver 
oil and creasote, to the treatment. The latter combi- 
nation is an excellent remedy for the so-called winter 
cough. 

Croup. — In connection with the employment of 
calcium sulphide, it is of service in favoring the expul- 
sion of membrane in the formative stages, but should 
not be carried to the point of emesis. A pill may be 
given every two hours to a child three years of age, 
unless it produces nausea and vomiting, when the in- 
tervals must be lengthened. 

Diarrhoea. — Useful after the acute symptoms have 
been subdued by other measures ; adapted to those 
cases in which a hepatic stimulant is indicated. 



IPECAC. I0 9 

Duodenal Catarrh. — Is an excellent remedy in 
this affection, and in alternation with hydrochloric 
acid and a regulated diet will prove curative ; a pill is 
taken after meals and between meals, with salines, as 
required. 

Dysmenorrhea. — Suited to the bilious cases, with 
diarrhoea and constipation alternating — an evidence of 
hepatic derangement ; a dose is given every three hours 
for a week or ten days before the expected period. 

Dyspepsia. — Ipecac stimulates and augments the 
secretions of the alimentary tract in a manner which 
makes it especially useful in the bilious variety of dys- 
pepsia ; a pill is taken every three hours. Alternation 
with creasote in pill-form is advisable. 

Hpistaxis. — Given to produce nausea, will relieve, 
but we now have more desirable remedies. 

Flatulence. — Is especially indicated in that form 
due to long-continued hepatic disorder, in which case 
it will be well to combine it with the biniodide ; a dose 
of ipecac is taken every three hours, and a dry diet 
advised. Children take a pill after meals, and, should 
nausea follow, the patient is instructed to lie on the 
right side, which favors emptying the stomach. 

Gastritis. — Especially indicated when a catarrhal 
condition is present; it is preferable here to active 
medicaments. A dose is taken every three hours, 
along with the occasional use of the biniodide and crea- 
sote, in pill-form. 

Hsematemesis. — When due to passive congestion 
dependent upon hepatic obstruction, ipecac will prove 
beneficial ; a dose is taken every three hours. Vica- 
rious haematemesis requires treatment of the cause. 

Haemorrhage, Post-partum.— When neither er- 
got, hot water, nor vinegar is at hand, large doses of 



IIO THE POCKET PHARMACY. 

ipecac may be given and followed by lukewarm water 
to produce vomiting ; although the method is rather 
heroic, it is efficacious. 

Intermittent Fever. — Can be used with benefit 
in alternation with the biniodide, and has a favorable 
influence upon the intestinal secretions during conva- 
lescence ; a dose may be given every three hours, or 
two pills after meals. 

Jaundice. — Should be given along with ox-gall and 
strychnine arseniate ; a dose of each, with two grains 
of dried ox-gall, may be given before meals, or two 
hours after eating. The biniodide will prove a valu- 
able adjunct to this treatment. 

Nymphomania. — If the patient can take the medi- 
cine without too much nausea, it will prove curative; 
a dose every two hours, with dry diet. 

Pertussis. — To be of service, it must be given to 
produce symptoms of nausea, and the plan is not there- 
fore recommended. A child five years of age can take 
a pill every three hours. 

Pharyngitis. — Sometimes useful in the form of a 
spray, using the wine, but it is offensive to many pa- 
tients, and causes nausea. 

Phthisis. — Used to overcome a torpid condition 
of the bowels and liver, alone or in combination with 
the biniodide ; one or two pills can be given at inter- 
vals of four hours for several days in succession. 

IRON ARSENIATE. 

Each tablet, pill, or granule contains one-twenty-fifth 
grai?i of the drug. 

Addison's Disease. — This remedy has been rec- 
ommended for the treatment of Addison's disease, but 



IRON ARSENIATE. ni 

it is doubtful if it will accomplish more than any other 
blood-tonic; a dose is taken every three hours. 

Albuminuria. — May be used as a hematinic in al- 
buminuria, care being taken to prevent constipation 
by the use of salines. In dropsies with high tension 
iron is not usually indicated. 

Amenorrhcea. — Useful in the amenorrhoea due to 
anaemia ; the addition of apiol and the biniodide to 
the treatment is often of benefit. 

Anaemia. — The value of iron in anaemic conditions 
can not be overrated, and yet too many failures occur 
because no attempt is made to prepare the system for 
its reception. Unless the hepatic function is near 
the norm, but little benefit will follow its use. Digest- 
ive ferments supply a temporary demand, by relieving 
the liver, or rather performing in part the work of that 
organ, but they do not strike at the cause ; rather, 
they partially overcome the effect of hepatic torpor. 
Purgatives aid materially by arresting the absorption 
of toxic substances. Much skill has been displayed in 
trying to discover the most suitable iron preparations 
calculated to meet the various symptoms presenting. 
Inasmuch as iron shows a tendency to accumulate in 
the liver, soluble preparations are to be preferred, or 
the dose must be so small that there will be no oppor- 
tunity for accumulation. When the conditions are 
favorable to the reception of iron preparations, the 
dosage is immaterial — a fact which goes to support 
the views advanced in connection with the doctrine of 
cellular therapy. 

Among the medicines included in this brochure, 
which should be used as a preliminary to the adminis- 
tration of iron in anaemia, attention is directed to ipe- 
cac, mercury biniodide, calomel, and arsenic sulphide. 



II2 THE POCKET PHARMACY. 

Iron arseniate may be combined with either of the fore- 
going remedies in the treatment of this disorder, and 
they will, when indicated, greatly enhance the advan- 
tages to be gained from the use of the remedy alone. 

Blepharitis. — Should be used in connection with 
the internal employment of calcium sulphide in the 
treatment of this affection, with a view to restore the 
hsemoglobin of the blood and eliminate waste products. 
A dose of each can be taken every three hours, along 
with suitable local medication. 

Bronchitis, Chronic. — Useful in combination with 
calcium sulphide in strumous children ; a dose of each 
three times a day. 

Cachexia. — A dose is given every three hours in 
combination with calcium sulphide, to be followed or 
alternated with creasote in pill-form, two grains three 
or four times daily. In case constipation is present, 
salines are indicated. 

Cancer. — Sometimes used internally for its tonic 
effect. 

Carbuncle. — Employed as a tonic and stimulant 
after the formation of pus, when calcium sulphide is 
exhibited, with or without quinine ; a dose is taken 
every three hours. It is more especially adapted to 
strumous patients and those who may be suffering from 
general debility. 

Caries. — This remedy is of decided value in com- 
bination with calcium sulphide in the treatment of 
caries. It may be alternated with the exhibition of 
phosphorus, but care must be given to the condition 
of the digestive apparatus and the functions of ex- 
cretion. 

Catarrh, Chronic Nasal. — Indicated after pre-^ 
liminary treatment by the spray and calcium sulphide. 



IRON ARSENIATE. 113 

The spray can be continued together with the calcium, 
but the virtues of creasote should be borne in mind. 

Cerebral Anaemia.— Is a remedy which might be 
expected to produce good results, basing our estimate 
on the well-known properties of the two drugs entering 
into the combination. To insure a practical knowl- 
edge of the objects sought in the treatment of this 
condition, brief reference must be made to the more 
prominent functional changes upon which it depends. 
Cerebral anaemia truly exists when the arterioles are 
contracted to the extent that the normal distribution 
of the blood is affected. On the other hand, symp- 
tomatic cerebral anaemia may exist with an increased 
supply of blood in the brain tissue, due to venous sta- 
sis. While both conditions produce similar symptoms 
in the main, and may depend upon organic changes 
difficult to distinguish, they are frequently due to 
faulty metabolism, with defective elimination. 

Iron arseniate is indicated only after the correc- 
tion of vaso-motor defects. Trinitrin, gelsemium, and 
strychnine arseniate are demanded to meet the first- 
described condition, while the biniodide, ipecac, and 
strychnine arseniate are indicated in the latter. A 
dose of iron arseniate is given every three hours along 
with bryonia when the meninges are implicated, as 
indicated by pains of a sharp, lancinating character. 
When the pain is dull, and accompanied by mental 
hebetude, calcium sulphide replaces the bryonia. 

Chlorosis. — As usually seen, this disease is symp- 
tomatic of defective metabolism. In addition to the 
employment of iron arseniate, there is a demand for 
hepatic stimulants like the biniodide along with anti- 
septics and blood-tonics, such as creasote and quinine. 
Salines are invaluable, as they have an important influ- 
8 



H 4 THE POCKET PHARMACY. 

ence upon the blood, increasing its alkalinity, by which 
its oxygen-carrying capacity is largely augmented. In 
addition, therefore, to the measures here recommended, 
oxygen inhalations are strongly advocated on alternate 
days. The iron arseniate should be given, a pill every 
three hours, until some symptoms of accumulation ap- 
pear, when symptomatic treatment can be permitted 
to take its place for a time. 

Chorea. — When the conditions are favorable to 
the administration of iron, a dose should be given 
hourly at first, gradually decreasing the frequency. It 
may be combined with atropine or cannabis indica. 
The rheumatic diathesis, or menstrual derangements, 
require in addition the use of cimicifuga in small doses. 

Climacteric Disorders. — Is of value only after 
derangements of the vascular tension have been cor- 
rected, and should be given for its tonic-alterative 
action, a pill after meals. 

Corneal Opacity.— Is generally given in combi- 
nation with calcium sulphide to strumous patients, or 
those suffering from debility; a dose of each three 
times a. day. 

Debility. — Useful in anaemic subjects when the 
condition of the digestive apparatus will tolerate it. 
For persons advanced in life, a dose may be given 
every three hours, with Rhine wine at dinner and 
supper. 

Diabetes Mellitus. — Useful in overcoming anaemia 
when it can be borne ; a dose three times a day. It 
will be serviceable in conjunction with the use of cal- 
cium sulphide and codeine sulphate. 

Dropsy. — Adapted to those cases occurring in ad- 
vanced life — an evidence of debility without cardiac 
or renal lesion. In case iron is not well borne, ar- 



IRON ARSENIATE. 115 

senious acid alone can be given, in doses of one one- 
hundredth of a grain every four hours. When iron is 
indicated, and is given in this form, a dose every three 
hours, the disorder will be favorably affected by the 
judicious employment of salines. Some cases will do 
better by the use of pilocarpine hydrochlorate hypo- 
dermatically, to increase the action of the skin and 
relieve the kidneys, but care must be exercised in this 
operation on account of the weak condition of the 
cardiac muscle. The preliminary exhibition of strych- 
nine arseniate or strophantus may be necessary to 
counteract the depressing effect of large doses of pilo- 
carpine. 

Dysmenorrhea. — A superior remedy when de- 
pendent upon anaemia ; it is also indicated in mem- 
branous dysmenorrhea, in combination with calcium 
sulphide — a method of treatment which is especially 
valuable when the uterus or its appendages are the 
subject of catarrhal changes. A dose of each is given 
every three hours, and the hot douche advised. 

Eczema. — May be given along with calcium sul- 
phide in the chronic cases in which anaemia is a promi- 
nent symptom ; a pill is given every three hours, so 
that five pills are taken daily. 

Elephantiasis. — A dose is given every three or 
four hours, along with mercury biniodide ; one dose of 
the latter daily. 

Emaciation. — A dose is taken three times a day 
with one dose of the biniodide once daily, and the in- 
halation of oxygen gas, five to ten gallons, every sec- 
ond day. Most satisfactory results will follow this 
plan of treatment. 

Emphysema. — Useful in patients with bronchitis 
and dyspnoea for its general tonic action on the air- 



n 6 THE POCKET PHARMACY. 

cells. May be advantageously combined with strych- 
nine arseniate and atropine sulphate, but not before 
the condition of the hepatic function has received at- 
tention. 

Enteritis. — Indicated during the period of con- 
valescence ; a dose every four hours. It would be 
advisable to add here a dose of calcium sulphide for 
its beneficial action upon mucous membranes. 

Epilepsy. — Indicated in the anaemic cases and in 
the class of patients requiring cannabis indica. Bro- 
mides produce a general anaemic condition, and as a 
consequence lose their influence upon the seizures. 
There follows in females uterine disturbances, and in 
males genital derangements, and these are succeeded 
by cerebral manifestations, all of which may be modi- 
fied by improving the condition of the blood. A dose 
of iron arseniate is given every three hours, and in 
suitable cases the addition of calcium sulphide will be 
an advantage. It is also useful in epileptiform ver- 
tigo along with the biniodide, a dose of each after 
meals, the bowels being regulated by the exhibition of 
a saline. 

Erysipelas. — The tincture of the chloride in large 
doses is a safe and efficient remedy, although some 
prefer to employ substantial doses of pilocarpine hy- 
drochlorate hypodermatically. 

Exophthalmus. — Will be of service in anaemic 
conditions ; but if we desire to strike at the origin of 
the trouble, we must interrogate the nervous system. 
It is suggested that ergot in the solid form be com- 
bined with the employment of iron arseniate. 

Flushing". — Useful in the case of young women 
whose menses are irregular, although there may be no 
pronounced anaemia. Ipecac will prove a valuable ad- 



IRON ARSENIATE. 



117 



dition to the treatment ; a dose of each every three 
hours. 

Glandular Enlargements. — In simple cases, non- 
tuberculous, iron arseniate may be given in combina- 
tion with calcium sulphide; a dose of each every three 
hours. 

Gout. — May be given in this affection for its tonic 
alterative action, provided the digestive apparatus will 
bear it. 

Gums, Spongy. — Is used to correct anaemic con- 
ditions upon which the disorder depends ; a dose is 
taken three times daily, with a solution of potassium 
chlorate as a mouth-wash. 

Headache. — Is adapted to that peculiar form of 
headache composed frequently of but two factors — in- 
digestion and anaemia — which manifests itself princi- 
pally in the forehead ; a dose is taken every hour for 
several hours. 

Heart, Dilated. — Useful to improve the general 
condition when iron can be borne ; a dose three times 
daily in combination with strophanthus or strychnine 
arseniate. 

Heart, Fatty. — Is given here for the same object 
as when we have to deal with cardiac dilatation. Treat- 
ment must be continued for some time, and the gen- 
eral condition of the patient requires attention. 

Heart, Valvular Disease of the.— Iron arseniate 
will be useful here to improve the nutrition; a dose 
three times daily. In case the iron is not well borne, 
arsenic alone may be used. 

Hectic. — Used to maintain the integrity of the 
blood and lessen the depression, along with measures 
calculated to destroy the poison to which the fever 
is due. 



Il8 THE POCKET PHARMACY. 

Hypochondriasis. — Adapted to the anaemic cases 
in which cannabis indica is valuable ; a dose of each 
every three or four hours. 

Hysteria. — Is given when the disorder depends 
upon a debilitated condition of the system ; a dose 
every three hours. 

Impotence. — Of decided benefit, either alone or 
in combination with cannabis indica and strychnine 
arseniate ; a dose of each may be given every three 
hours. In some cases damiana may be substituted for 
the strychnine preparation. 

Intermittent Fever. — Exceedingly useful in alter- 
nation with quinine hydrochlorate, after the arrest of 
the chills ; a dose is given every three hours. 

Leucorrhcea. — A valuable remedy; should be 
given in combination with calcium sulphide, a dose of 
each every three hours, along with suitable local treat- 
ment. A solution of the peroxide of hydrogen in the 
form of a douche is excellent. 

Lichen.— Adapted to chronic cases, with suitable 
local treatment, and one dose daily of the biniodide. 

Lupus. — Used for its alterative action, along 
with the biniodide, to favor elimination. Local treat- 
ment will be required to arrest the progress of the 
disease. 

Mania. — Used after the acute stage to meet 
anaemic conditions, alone or in combination with can- 
nabis indica. 

Melancholia. — Is of benefit in anaemic conditions, 
alone or with cannabis indica ; a dose every three 
hours. 

Menorrhagia. — The most important of all reme- 
dies when well tolerated, but the system must be pre- 
pared for its reception, as previously intimated ; may 



IRON ARSENIATE. ng 

be advantageously combined with strychnine arseniate, 
a dose of each every four hours. 

Muscat Volitantes. — Should be given in anaemic 
conditions and at the climacteric; a dose every four 
hours along with the biniodide. 

Nervousness. — Used in anaemic conditions ; sev- 
eral doses may be taken half an hour apart to insure 
a quiet night free from fidgets. 

Neuralgia. — Adapted to those cases in which 
anaemia is a factor ; a dose is given every two hours, 
alone or in combination with acetanilide compound, 
but the latter should be discontinued as soon as the 
pain begins to disappear. 

Ozsena. — May follow or be alternated with the ex- 
hibition of calcium sulphide ; a dose of each every four 
hours. 

Pemphigus. — Has a tendency to improve cuta- 
neous nutrition, and the blood ; a dose every four hours. 

Perspiration. — Useful when due to anaemia, alone 
or with quinine hydrochlorate ; a dose of each every 
three hours, with suitable nourishment. 

Pharyngitis. — Applicable in anaemic cases ; a pill 
is given every four hours, alone or with calcium sul- 
phide. 

Phthisis. — Should be given to improve the con- 
dition of the blood, in the expectation that along with 
other appropriate medication consolidation would be 
arrested. 

Pityriasis. — Will be found useful along with the 
biniodide to act as a hepatic stimulant. Suitable local 
treatment will be required. 

Pleurodynia. — When associated with uterine dis- 
order and anaemia, this remedy is curative ; a dose is 
given every three hours, with atropine sulphate. 



120 THE POCKET PHARMACY. 

Psoriasis. — Indicated in anaemic cases after the 
preliminary use of mercury biniodide, alone or with 
sulphur in some form. A potash instead of a soda 
soap is recommended. 

Puerperal Mania. — Indicated when there is 
anaemia ; it may be given with quinine hydrochlorate 
and cannabis indica. 

Purpura. — May be used as soon as the condition 
of the system will permit, alone or with arsenic sul- 
phide. 

Rheumatoid Arthritis. — Very efficient as an alter- 
ative, but must be given for a long time. Diet and 
hygiene are of the utmost importance. 

Rickets. — Should be given along with the phos- 
phates or hypophosphites, or phosphorus and quinine 
hydrochlorate. 

Scarlet Fever. — Is given during the period of 
convalescence, if the condition of the digestive organs 
will permit. In the case of intestinal disturbances oc- 
curring, copper arsenite should be substituted for it 
until improvement takes place. 

Scrofula. — The arseniate should be given continu- 
ously for a long time, alone or with other medication. 
The free use of fats is very necessary ; creasote and 
the peroxide of hydrogen may be used as intestinal 
antiseptics, but the latter must not be given continu- 
ously, on account of its effect upon the teeth. 

Scurvy. — A most appropriate remedy along with 
suitable dietary ; occasionally it may be alternated to 
advantage with the mineral acids or creasote. 

Spermatorrhoea. — Useful in functional impo- 
tence in combination with cannabis indica and strych- 
nine arseniate, or damiana and ergot, according to the 
indications present. 



MERCURY BINIODIDE. 12 1 

Tabes Mesenterica. — Is of value as a general 
tonic, but for the most part the treatment adapted to 
tubercular invasion must be pursued — creasote and 
inhalations of chlor-arsenite of copper, with small doses 
of the biniodide and cod-liver oil. 

Tiodouloureux. — Indicated in anaemic cases. The 
condition of the bowels should receive attention, and 
hygienic regulations must be followed in order to place 
the patient in as favorable a condition as possible. 
Phosphorus is a valuable remedy under certain con- 
ditions. 

MERCURY BINIODIDE. 

Each tablet, pill, or granule contains one one-hun- 
dredth grain of the drug. The ointment of mercury 
biniodide is prepared in the proportion of one part to 
nine parts of benzoinated lard, and is used in accord- 
ance with the directions given under the different dis- 
eases to which it is adapted. When employed to pro- 
duce a blister, antiseptic treatment must be followed. 

Acidity of the Stomach.— Is a useful remedy 
when acidity is due to biliary derangement, with pale, 
clay -colored stools, with or without constipation. 
Adults take a pill two or three times a day, while chil- 
dren do remarkably well on one pill daily in divided 
hourly doses. 

Anaemia. — A valuable adjunct to iron arseniate in 
the treatment of all anaemic conditions, but more espe- 
cially is it useful when hepatic torpor is marked and 
of long duration, as shown by injected conjunctivae, 
sallow skin, mental hebetude, drowsiness during the 
day, with persistent insomnia at night. Vaso-motor 
tonics, strychnine arseniate, ergotin, and quinine hy- 



I2 2 THE POCKET PHARMACY. 

drochlorate may be demanded, and the importance of 
salines should not be overlooked. Evidences of mal- 
nutrition must be met by appropriate remedies, suit- 
able diet, and fresh air. 

Aphthae. — A few doses of one one-hundredth grain 
daily (divided) may be used as a preliminary to the 
exhibition of copper arsenite. 

Asthma. — The biniodide is an efficient alterative 
in both bronchial and in true asthma after the subsi- 
dence of the active dyspnoea; a pill should be given 
every two or three hours, and salines in moderate quan- 
tity given daily. 

Biliousness. — Is especially useful when the stools 
are clay-colored and pasty. Alternation with small 
doses of podophyllum will be helpful, but we must not 
omit the morning saline. The latter should be no 
more than sufficient to gently relax the bowels in the 
morning after the patient has eaten breakfast ; more 
active treatment will eventually result in injury to the 
patient, and should be discouraged. 

Boils. — The biniodide is of immediate benefit in 
conjunction with salines in arresting the disposition to 
form boils ; a dose may be taken three times a day for 
several days, and followed by the exhibition of crea- 
sote in pill-form, two grains after meals. 

Bone, Diseases of. — In exostosis of recent origin 
following injuries the biniodide should be given inter- 
nally, two or three pills daily, with the local use of the 
ointment at intervals of a week to favor resolution. 
The ointment of the biniodide, one part to ten of ben- 
zoinated lard, must be well rubbed in for half an hour, 
and the parts subsequently washed with warm water 
and soap. This treatment will usually be sufficient 
to set up sufficient counter-irritation, and has proved 



MERCURY BINIODIDE. 



123 



an effective local application in cases of this char- 
acter. 

Bubo. — A pill should be taken every three or four 
hours, and in addition the patient takes a dose of mag- 
nesium sulphate every morning before breakfast for 
several days. If, after a reasonable length of time, 
absorption does not take place, and pus threatens, the 
ointment may be applied externally, as just indicated. 
A single application will generally suffice to prepare 
the disorder for surgical treatment, which must be 
practiced under antiseptic measures, and followed by 
the exhibition of calcium sulphide. 

Bunion. — A dose is given three or four times a 
day, with the application of the compound tincture of 
iodine locally, and the exhibition of salines in moderate 
dosage. The affected area must be properly protected 
during treatment by a suitable plaster, so as to avoid 
pressure. 

Bursitis. — A dose is given three or four times 
daily, with the local use of the ointment. Aspiration 
may hasten recovery if practiced before treatment is 
begun, in which case it will be better to depend upon 
the compound tincture of iodine rather than the oint- 
ment. 

Cachexia, Malarial.— Treatment is begun by giv- 
ing three or four pills daily, conjoined with salines, 
and followed by quinine hydrochlorate. Later, the 
treatment for simple cachexia should be adopted. This 
method of treatment is especially indicated in syphi- 
litic cases. (See Cachexia, under Iron Arseniate.) 

Calculi, Biliary. — A dose is taken every three 
hours along with olive oil. The ointment is used over 
the liver in some cases with marked benefit, but olive 
oil should be administered as soon as the condition of 



I24 THE POCKET PHARMACY. 

the stomach will permit. For the emergency, a hypo- 
dermatic of morphine and atropine is required to re- 
lieve pain and lessen tension. For the vomiting which 
occurs, large draughts of hot water must be used, alone 
or in combination with copper arsenite in solution. 

Carbuncle. — In the treatment of carbuncle several 
plans suggest themselves, depending upon the physical 
condition of the patient and the domestic or other 
treatment to which the disorder has been subjected. 
Generally the physician is consulted too late for abort- 
ive treatment to be adopted, and it will be found that 
much harm results from the indiscriminate and reck- 
less use of poultices. The biniodide will often be suf- 
ficient to abort, if given early enough with a saline, 
and no poultices have been applied. In connection 
with the internal use of the drug, the ointment is ap- 
plied locally, as previously directed — a plan which will 
either abort or hasten the formation of pus. When 
suppuration has taken place, however, surgical inter- 
ference is demanded, and calcium sulphide is to be 
substituted for the biniodide. In tedious cases, as 
seen in strumous subjects, the biniodide ointment will 
generally be required ; it should be thoroughly rubbed 
in, and all removed with soap and water in half an hour. 

Cerebral Anaemia. — A condition simulating cere- 
bral anaemia — really venous stasis — is best considered 
under the head of Congestion (q. v.). 

Cerebral Congestion. — A useful remedy in cere- 
bral congestion of the passive variety. In many cases 
it has advantages over calomel or the alterative pill. 
A dose should be given every two or three hours along 
with ipecac, and salines judiciously added. Local 
blood-letting will aid materially, and the use of strych- 
nine arseniate must be borne in mind. 



MERCURY BINIODIDE. I2 5 

Chancre. — If the sore is seen early enough, abort- 
ive treatment may be tried; give a pill every three or 
four hours, with salines at appropriate intervals, ap- 
plying at once pure nitric acid. Later the sore may 
be treated with iodoform, or aristol in case the former 
is objectionable. Diet is of greatest importance in this 
treatment, and the use of alcoholic stimulants must be 
positively interdicted. 

Chancroid.— The same method is followed as in 
the abortive treatment of chancre. 

Chilblains. — A pill is given three times daily, with 
the ethereal solution of aristol applied locally, the 
parts to be properly protected from pressure and ex- 
posure. The strength of the solution should be from 
one to two drachms to the ounce. 

Chlorosis. — A pill is given three times daily, along 
with iron arseniate and creasote on alternate weeks ; 
the bowels must be regulated by salines or other suit- 
able medication. 

Cholera, Asiatic. — The biniodide is recommended 
for trial in this disease, on account of its antiseptic 
properties and its action upon the liver. Two pills 
should be dissolved in four ounces of water, and a tea- 
spoonful given every ten minutes at first, then less 
frequently, alone or in alternation with copper arsenite. 

Cirrhosis. — Is probably our most effective remedy, 
on account of its stimulant action upon the hepatic 
cells, but it must be given in small doses, say three 
pills daily, for a period of two weeks. Appropriate 
living must be insisted upon. 

Climacteric Disorders. — Useful as a hepatic stim- 
ulant and intestinal antiseptic. In addition to a dose 
after meals, the ointment may be applied at intervals 
of a few days over the region of the liver, and salines 



126 THE POCKET PHARMACY. 

used in moderation to favor elimination and assist in 
maintaining the alkalinity of the blood, by which its 
oxygen-carrying capacity is increased. Along with 
this method of treatment small doses of cimicifuga will 
often be of advantage. 

Colic, Lead. — May be alternated with potassium 
iodide along with salines, after the emergency has 
passed ; a pill every four hours. 

Corneal Opacity.— When there is a syphilitic his- 
tory, a pill should be given three times a day. 

Croup.— Of decided advantage as an antiseptic in 
connection with calcium sulphide and ipecac; a pill is 
dissolved in the mouth every two or three hours until 
the formidable symptoms have disappeared. 

Debility. — Inasmuch as this morbid complexus is 
frequently due to non-elimination, an alterative remedy 
is indicated ; a dose is given daily along with arsenic 
sulphide, and a saline as required. 

Diabetes Insipidus. — Should follow the exhibition 
of ergot in syphilitic cases ; a dose three times a day, 
with salines as indicated. 

Diarrhoea. — In obstinate cases of the bilious type 
a dose may be given daily, in divided hourly doses, in 
connection with other suitable treatment, for its anti- 
septic and cholagogue action. Podophyllum and qui- 
nine take its place when the stools are dark and of- 
fensive. 

Diphtheria. — As soon as constitutional symptoms 
present, indicated by rapidly increasing elevation of 
the temperature, a dose is given dissolved in the mouth 
at intervals of two hours, local treatment being con- 
tinued at regular intervals. 

Dyspepsia. — This remedy possesses antiseptic and 
cholagogue properties, and has therefore a twofold ac- 



MERCURY BINIODIDE. 



127 



tion upon the morbid complexus known as dyspepsia; 
a dose is given every four hours for several days pre- 
vious to the employment of ipecac or the digestive 
ferments. The latter are of permanent value only after 
a healthy condition of the hepatic function has been 
established. 

Ecthyma. — A dose is given every four hours along 
with a dose of quinine hydrochlorate every two hours, 
the bowels being gently relaxed by a saline. 

Eczema. — Beneficial in all cases characterized by 
hepatic torpor and a costive habit of the bowels. A 
pill is given three times a day for a week, and followed 
by creasote, two grains three times daily for the same 
period. 

Elephantiasis. — A dose is taken daily in conjunc- 
tion with iron arseniate. 

Emphysema. — Should be used in combination with 
strychnine arseniate and atropine sulphate, and the 
exhibition of salines to relieve hepatic congestion and 
lessen the embarrassment of the right side of the 
heart. 

Endocarditis. — Will be of service on account of 
its influence upon the stomach and liver, and upon the 
exudation like potassium iodide ; a pill is taken three 
or four times a day. 

Enteritis. — In torpid conditions of the liver, along 
with an anodyne — codeine sulphate — the biniodide in 
small doses will serve a useful purpose, although podo- 
phyllum may occasionally take its place, indicated by 
the character of the stools. 

Epilepsy. — It is indicated in this disease whenever 
we have a history of syphilitic infection, and with po- 
tassium iodide and salines much can be accomplished. 
It should be used along with iron arseniate in those 



r2 8 THE POCKET PHARMACY, 

cases of epileptiform vertigo which proceed from de- 
rangement of the digestive apparatus. 

Fever. — Always a valuable remedy in the begin- 
ning of feverish conditions, when the true character of 
the malady is not frankly expressed by the symptoms 
and physical signs. It is, moreover, a very efficient 
remedy at the commencement of typhoid fever and 
malarial disorder ; a dose is taken three or four times 
a day. 

Flatulence. — In connection with ipecac or crea- 
sote, the biniodide is a most useful remedy when we 
have to deal with a " slow liver " ; a pill is taken two 
or three times a day for several days, then omitted for 
several days. 

Gastralgia. — A daily dose along with quinine 
hydrochlorate is indicated in simple debilitated con- 
ditions, and three doses daily for several days when 
dependent upon malaria. Sodium salicylate is indi- 
cated when the debility is complicated with subacute 
or chronic rheumatism. 

Gastric Ulcer. — Is used here in connection with 
the exhibition of digestive ferments for its antiseptic 
action and its influence upon the liver ; a dose is taken 
three times a day in alternation with creasote. 

Glanders. — Indicated for the purpose of relieving 
hepatic torpor, and for its antiseptic action upon the 
stomach ; two pills are dissolved in water and taken 
during the day in divided hourly doses. The solution 
(i to 4,000), applied locally, is invaluable. 

Glandular Enlargement. — Very useful in the 
case of breaking down " scrofulous " glands. It will 
sometimes show good results in tubercular enlarge- 
ments, used internally and applied locally in the form 
of the ointment. Along with creasote and attention 



MERCURY BINIODIDE. 



129 



to diet and hygiene, a dose of the biniodide should be 
taken three times a day. 

Gleet. — In syphilitic cases without stricture, a solu- 
tion (1 to 4,000) should be used locally several times a 
day, but it will be necessary to practice dilatation. 
This plan of treatment is adapted only to recent cases 
where the contraction is not marked. 

Goitre. — The remedy is taken three times a day, 
and the ointment applied locally every three or four 
days. Creasote is valuable in alternation with the 
biniodide, but with marked vaso-motor disturbances in 
the region of the thyreoid gland it is advisable to 
exhibit ergot in the solid form, which affords far 
better results than when it is given in the form of a 
liquid. 

Gonorrhoea. — Useful in the form of a solution 
(1 to 4,000) at short intervals, say two hours. It may 
be used in alternation with a weak solution of zinc 
chloride, half a grain to the ounce, diluted with an 
equal quantity of hot water. 

Gout. — Is of value to favor the absorption of in- 
flammatory products; a dose three times daily with the 
local use of the ointment. 

Haematemesis. — Is given to remove or correct he- 
patic congestion, with ergot hypodermatically for the 
emergency. Two or three pills should be dissolved in 
hot water and taken in teasponful doses during the 
day. 

Haemorrhoids. — Of decided benefit when associ- 
ated with portal congestion and torpid liver. A pill is 
given three times daily, and locally an ointment, in 
capsules, of teucrium scordium is applied. Salines may 
be cautiously employed, or the use of large enemata c£ 
tepid water. 
9 



130 



THE POCKET PHARMACY. 



Headache. — In the purely bilious cases the bin- 
iodide is most efficacious for the reason that it relieves 
the cause. The most satisfactory method consists in 
giving one to four pills in solution daily in divided 
doses, with salines as required. A valuable addition 
will consist in the use of ox-gall, two or three grains, 
with a dose of strychnine arseniate, before or about 
two hours after meals. 

Heartburn. — Indicated when the disorder is asso- 
ciated with hepatic derangement ; one pill is taken in 
moderately warm water at once, preferably in the 
morning before breakfast. 

Heart, Palpitation of the. — Useful when due to 
hepatic derangements and delayed stomach digestion ; 
a pill is taken in hot water before breakfast, and salines 
used as indicated. 

Hepatitis. — A very useful remedy in connection 
with olive oil or a purified petrolatum product. Two 
or three pills are taken daily, in the form of a solution, 
so that the entire quantity may be distributed through- 
out the day in hourly doses. The free use of the oint- 
ment over the region of the liver will materially shorten 
the period of the disease and hasten convalescence. 

Hydrocephalus, Chronic. — Should be valuable 
as an alterative to remove from the system effete 
products. 

Inflammation. — Indicated in the later formative 
period when the affected structures lie deep-seated 
and involve serous structures, and especially is it use- 
ful in syphilitic cases. Two or three pills are given 
daily in solution — hourly doses. 

Intermittent Fever. — A most valuable hepatic 
stimulant and antiseptic ; in connection with full doses 
of quinine, a pill should be taken three times a day 



MERCURY BINIODIDE. 131 

every other day for a week, then less frequently. In 
case the bowels are not freely moved, a saline is given 
in the early morning. The ointment applied over the 
liver is sometimes an important adjunct to quinine. 

Intertrigo. — Is used locally in the form of a weak 
solution (1 to 4,000), the parts to be dusted with aristol 
or boric acid. Dry treatment is better, as a rule, than 
moist. 

Iritis. — Is a superior remedy ; three pills are taken 
daily in divided hourly doses. 

Jaundice. — Is given in alternation with nitro-hydro- 
chloric acid or ipecac to those patients who can not 
well take the phosphate of soda, although the biniodide 
will often accomplish much in relieving the condition 
after the failure of sodium phosphate. Salines should 
be judiciously employed, and olive oil when there is a 
suspicion of gall-stones. 

Meningitis, Cerebral. — Is used to favor absorp- 
tion after the subsidence of acute symptoms ; a pill is 
taken night and morning along with small doses of 
pilocarpine hydrochlorate. 

Menorrhagia. — A valuable medicine when the dis- 
order is accompanied by, or associated with, hepatic 
obstruction ; a dose should be taken three times daily 
in addition to indicated remedies. 

Muscae Volitantes. — When occurring in connec- 
tion with rheumatism at the climacteric, either the 
biniodide or sodium salicylate should be given. When 
ordering the latter, it is important that the physician 
should specify that it be prepared from the true or 
natural salicylic acid, made from oil of wintergreen 
and chemically pure bicarbonate of soda ; no other 
combination is adapted to internal medication. 

Myelitis. — Useful in the subacute stage to favor 



132 



THE POCKET PHARMACY. 



absorption ; a dose is taken once or twice daily along 
with phosphorus or strychnine arseniate. 

Nausea. — Occasionally, when dependent upon 
hepatic obstruction, the biniodide will prove superior 
to copper arsenite. Children can take it in solution ; 
adults take a single pill dissolved in a glass of water. 

Neuralgia. — In connection with quinine in malari- 
al neuralgias, a pill is taken at bed-hour, and the bowels 
relieved by salines. 

Nodes. — Used locally in the form of an ointment, 
just short of producing a blister, along with a pill three 
times daily. 

Otorrhoea. — Especially valuable in syphilitic cases. 
A pill is taken three times a day, with Baunscheidtis- 
mus or some other form of counter-irritation applied 
to the mastoid process. 

Ozaena. — Very effective in syphilitic cases ; a pill 
is taken three times a day, along with the local use of 
the spray, using a solution in the strength of i to 
4,000. 

Paronychia. — Best adapted to syphilitic cases ; a 
pill is taken every four hours along with the applica- 
tion of the ointment locally for two days in succession 
— half an hour each time. The compound tincture of 
iodine may be used in place of the ointment, although 
few cases will do better under this method of treat- 
ment than, when the clay dressing and calcium sul- 
phide are employed. 

Parotiditis. — Will be useful in the later stages 
to favor absorption, pilocarpine hydrochlorate being 
adapted to the early stage of the disease. 

Periostitis. — Will prove beneficial in many cases, 
but the digestive apparatus and diet should receive 
proper attention. A dose is given three times a day, 



MERCURY BINIODIDE. 



133 



with the local use of the ointment in those cases where 
the disease is superficial and of recent origin. 

Peritonitis. — Used in the later stages and during 
convalescence, to favor absorption and arrest fibrous 
exudation ; a dose two or three times a day. 

Phlebitis. — Used internally and locally in the form 
of the ointment to favor absorption. Local blood- 
letting may be advisable. 

Phlegmasia Alba Dolens. — For preliminary 
treatment, the same plan may be adopted as in the 
case of phlebitis, with morphine and acetanilide com- 
pound to allay pain and reduce temperature. 

Pleurisy. — Given during the later stages and in 
convalescence to aid absorption. In lingering cases 
of dry pleurisy the ointment may be applied externally 
with advantage. 

Pneumonia. — Especially indicated when convales- 
cence has begun, to favor the absorption of inflamma- 
tory products. A dose is taken twice a day, along with 
a nutritious diet. 

Prolapsus Ani.— As this disorder is often due to 
a torpid condition of the liver and constipation, the 
biniodide, in conjunction with salines and strychnine 
arseniate, will prove of benefit. 

Prostate, Enlarged.— Gives the best promise of 
success, provided complications, such as pelvic con- 
gestions, etc., can be remedied. A dose is taken two 
or three times a day along with small doses of saw 
palmetto (Sabal serrulatum). 

Prurigo and Pruritus. — Should always be adopt- 
ed in the beginning of internal medication, alone or in 
combination with ox-gall, quinine, and strychnine 
arseniate, the bowels being relieved by salines. 

Psoriasis. — Should be employed as a preliminary 



134 



THE POCKET PHARMACY. 



treatment, to which is added later arsenic and the sul- 
phides, along with suitable local applications as indi- 
cated for prurigo and pruritus. 

Puerperal Fever. — Will be useful after employ- 
ment of quinine and salines, to prevent absorption of 
poisonous materials from the intestinal tract, overcome 
tympanites, and stimulate the hepatic function. 

Pyrosis. — Useful when occurring in bilious patients; 
a dose three times a day. 

Rheumatism, Acute. — May be used cautiously in 
the after-stage of the disease to favor absorption. 

Rheumatoid Arthritis. — When given along with 
the free use of lithia water, seems to have a favorable 
influence upon the inflammations affecting the joints. 

Scarlet Fever. — Used in the beginning in the 
form of a solution, for its antiseptic influence upon the 
throat structures, and as a stimulant of the liver, the 
bowels being relieved by a saline when necessary. 

Sciatica. — Useful in syphilitic cases along with 
other treatment of a supporting character. 

Scrofula. — Given internally and used locally in the 
form of the ointment, will have a favorable influence 
upon the enlarged glands, but improvement progresses 
slowly. Care must be taken to note that these enlarge- 
ments are non-tuberculous. 

Spinal Paralysis and Softening.— Is used to 
aid absorption after inflammatory action affecting the 
cord and meninges. It may be advantageously alter- 
nated or combined with phosphorus. Ergot is added 
when hyperaemia of the cord exists. 

Splenic Affections. — Given internally and the 
ointment applied locally, is very effective in simple en- 
largement, and is of some benefit when hypertrophy is 
associated with malarial toxaemia. 



MERCURY BINIODIDE. 



135 



Stomatitis. — Should be used in the form of a solu- 
tion, so as to bring the medicament into contact with 
the ulcerations. It is especially valuable in syphilitic 
ulcerations; a pill is dissolved in the mouth three times 
a day. 

Strabismus. — In cases where but a single nerve is 
affected, and a syphilitic history can be traced, the bin- 
iodide may be used with a reasonable prospect of suc- 
cess. 

Strophulus. — Indicated when the stools are pale 
and watery, and where there is a tendency to attacks 
of looseness of the bowels. A child three years of age 
or under takes one pill in solution, in divided hourly 
doses, every day. 

Suppuration. — Indicated in all deep-seated inflam- 
mations, especially in syphilitic cases. 

Synovitis. — A remedy possessing great utility in 
strumous and syphilitic cases. As many of these are 
seen only in the subacute or chronic stage, it will be 
found advantageous to add to the internal administra- 
tion of the drug the local use of the ointment, which 
is usually sufficient to effect a cure and remove all in- 
durations. 

Syphilis. — Compares favorably in its action with 
other mercurials which are used internally. In many 
cases, however, it is superior, although it should not 
be used continuously for a long period ; nor is it neces- 
sary to produce ptyalism. A dose two or three times 
a day will usually be sufficient ; when more is given, 
the administration of the drug must be discontinued 
from time to time. 

Testicle, Disease of the.— Adapted to the later 
stages of the acute cases, and always in subacute and 
chronic orchitis and epididymitis; a pill is taken three 



136 THE POCKET PHARMACY. 

times a day along with salines. When a counter-irritant 
is demanded for its revulsive effect, tincture of iodine 
may be used, but is less efficient than the ointment 
previously recommended. The hair should be cropped 
close, and the ointment applied by rubbing with the 
fingers; at the expiration of half an hour, the whole is 
washed off with warm water and Castile soap. In case 
no marked effect is produced, this treatment is repeated 
on the day following. Abrasions of the skin due to 
this treatment should be treated antiseptically, using 
for the purpose iodoform or aristol in the form of a 
dusting powder. 

Tinea Favosa. — May be used locally in the form 
of a solution, or a weak ointment may be applied. 

Tonsillitis. — In acute cases, after the employment 
of vascular sedatives (aconite, gelsemium), small doses 
in solution are indicated along with the exhibition of a 
saline. One or two pills are dissolved in four to six 
ounces of water, and a teaspoonful given at intervals 
of ten minutes for the first hour, then every hour for a 
day or two. This treatment will not interfere with in- 
ternal medication of a symptomatic character, and will 
have a tendency to modify the character and severity 
of the disease. 

Trismus. — Should be used when occurring in in- 
fants — the bowels being relieved by salines, to stimu- 
late the liver and carry off poisonous products. 

Typhoid Fever. — Is indicated when there is he- 
patic obstruction accompanied by profuse, watery, foul- 
smelling stools. One or two pills are dissolved in 
three ounces of water, and of this solution the patient 
takes a teaspoonful every ten minutes for an hour 
every morning, and afterward at intervals of an hour 
during the day and night while awake. Nitro-hydro- 



MORPHINE HYDROCHLORATE. 



137 



chloric acid is a suitable remedy to follow the employ- 
ment of the biniodide. 

Vomiting". — In the case of symptomatic vomiting, 
as that occurring from hepatic obstruction, which is 
not infrequently an important factor in the vomiting 
of pregnancy, the biniodide should be used in the same 
manner as copper arsenite. It is also indicated for 
the relief of vomiting of drunkards; a pill is dissolved 
in water, and taken half an hour before breakfast. 
There are in addition many other causes which pro- 
duce vomiting, but it is believed that the directions 
given for the employment of the biniodide and copper 
arsenite will enable the physician to select proper medi- 
caments. Since a special section on the vomiting of 
pregnancy would be nothing more than a repetition of 
much that has already been written in this little mono- 
graph, the conclusion has been reached that it might 
with profit be omitted. 



MORPHINE HYDROCHLORATE. 

Each tablet, pill, or granule contains one-fiftieth 
grain of the drug. 

After-pains. — In the absence of blood-clots in the 
uterine cavity, and when the patient is of a nervous 
temperament, indicated by restlessness, insomnia, and 
panphobia, morphine hydrochlorate may be used with 
much benefit. It allays pain and nervous irritability, 
and favors repose, but should not be taken in sufficient 
amount to arrest the secretions. Cases of this char- 
acter will progress favorably by substituting for the 
narcotic small doses of the bromides or acetanilide 
compound at the expiration of twenty-four hours. In 



I38 THE POCKET PHARMACY. 

administering morphine for this disorder, under the 
special conditions mentioned, a dose should be given 
every ten minutes for an hour or two, but it must not 
be continued longer than twenty-four hours. 

Asthma. — Morphine and atropine, one quarter and 
one one-hundred-and-fiftieth grain, respectively, of the 
sulphate, given hypodermatically, will often cut short 
a paroxysm of asthma, after which a tablet of each 
mentioned here (gr. z / so and gr. x / 500 ) can be given with 
benefit; but there is a danger that the habit will be 
formed. It is useful as a temporary expedient when 
the neurotic element predominates. 

Bronchitis, Chronic. — Morphine is sometimes of 
value alone in chronic bronchitis, but usually it is given 
along with calcium sulphide or with an expectorant. 
It is also of service when there are indications for the 
employment of creasote or one of the preparations of 
petroleum, although occasionally it will be found that 
codeine sulphate will take its place. 

Cholera, Asiatic. — Used to relieve the cramps 
when bryonia and codeine sulphate in turn fail to pro- 
duce the desired effect. Undoubtedly, morphine and 
atropine hypodermatically in the early stages of the 
disease exercise a salutary influence, but later on they 
are used only to meet special indications, the real 
treatment being directed to the prevention of absorp- 
tion through the various channels, more especially the 
liver and intestinal tract. 

Cholera Morbus. — May be demanded in addition 
to copper arsenite when there are paroxysmal pains 
affecting the small intestine, with profuse discharges 
from the bowels, vomiting, and rapid pulse, with slight 
fever. A dose is given every ten minutes for an hour, 
which will generally be sufficient, although it can be 



MORPHINE HYDKOCHLORATE. 



139 



continued at longer intervals if deemed necessary. 
Codeine sulphate, in doses of one-tenth grain, may 
sometimes take its place for this special purpose, and 
carries with it no danger. 

Colic, Intestinal. — Used along with atropine, the 
combination possesses valuable anodyne and antispas- 
modic properties; and previous to the discovery of the 
therapeutic properties of copper arsenite, and the prin- 
ciple of auto-infection, this plan of treatment was al- 
most universal, but must now be considered obsolete. 
In so simple a disorder as intestinal colic the use of 
morphine may arrest the vermicular or peristaltic 
movements to such an extent that absorption of poi- 
sons will rapidly take place, and thus precipitate upon 
the patient a disease he wished to avoid. 

Constipation. — Is best adapted to those cases in 
which we have to contend with pelvic complications, 
rectal, ovarian, and vesical irritation, with a tendency 
to arrest the secretions of the lower bowel ; a single 
pill is taken at bed-hour. 

Delirium. — Useful as a temporary expedient in 
combination with bromides, or alternated with them, 
to avoid bromism, until the critical period has passed; 
a dose is given every ten minutes for an hour, and 
repeated as occasion requires. 

Diabetes Insipidus. — Small doses are sometimes 
advantageously combined with the ergot treatment in 
nervous patients; a pill every two hours. 

Dysmenorrhcea. — Is not frequently called for in 
this disease, but may prove useful in those cases where 
the disorder is due to pelvic complications, haemor- 
rhoids, constipation, etc. ; a pill is taken every ten min- 
utes for an hour, and followed by medication calculated 
to relieve the cause. 



140 



THE POCKET PHARMACY. 



Dyspepsia. — There is a form of dyspepsia occur- 
ring in those who are the subjects of chronic disease 
of the abdominal viscera, cirrhosis, carcinoma, etc., in 
which patients complain of " sinking at the stomach/' 
that is temporarily relieved by taking food, where 
morphine is of value; it is not curative, however. A 
dose is given every two hours, along with a dose of 
atropine three times a day, to prevent constipation. 
This treatment sometimes succeeds admirably where 
codeine signally fails. 

Dysuria. — May be given along with camphor, 
when the latter is indicated ; a dose of each every ten 
minutes for an hour, after which the camphor alone is 
continued. 

Enteritis. — Is sometimes indicated in the acute 
cases with severe dull and occasional lancinating pains, 
showing that both mucous and serous structures are 
involved; a dose is given every ten minutes for an 
hour, then less frequently. Codeine sulphate in doses 
of one-tenth grain would be indicated here on account 
of its supposed influence over abdominal pain, and it 
has been used frequently in such cases where morphine 
was contra-indicated. 

Fever. — Useful in place of the bromides for the 
muttering delirium of typhoid, a condition often de- 
pendent upon lack of sufficient food. Morphine, by 
allaying the craving for food, will tide the patient 
over a critical period, while bromides and other medica- 
ments of this class would have no effect. One or tw r o 
pills every half-hour for several hours will produce a 
marked change in the condition of the patient, but 
attempts must be made to improve nutrition. 

Gastralgia. — Is sometimes curative in this dis- 
ease, but is objectionable on account of the danger of 



MORPHINE HYDROCHLORATE. 



141 



producing the " habit." As a rule, it should never be 
given to patients under sixty years of age for the relief 
of this disorder, and even then its employment must 
be restricted, and wholly under the charge of the phy- 
sician. 

Gastric Ulcer. — Relieves pain and creates a feel- 
ing of well-being, but it would be better to substitute 
codeine sulphate for it, especially in those who have 
not passed middle life. 

Gastritis. — Not so well adapted to relieve the pain 
as acetanilide compound, although codeine sulphate 
may be substituted for morphine in an emergency ; 
one-tenth grain every half-hour for several hours. 

Gout. — May be required in special cases where 
acetanilide compound is contra-indicated, but should 
not be long continued — say a dose every ten minutes 
for an hour. 

Haemoptysis. — May be used in small doses in an 
emergency, but has no curative value. 

Haemorrhage, Intestinal. — Allays the pain and 
arrests peristalsis, if given in substantial doses, but 
care must be taken not to mask the disease by the 
narcotic. 

Haemorrhage, Post-partum— Is a very efficient 
remedy for producing uterine contractions after par- 
turition, an effect doubtless due to its influence over 
pain. Irritation being removed, the uterine muscle 
exercises its inherent property and contracts. The use 
of a teaspoonful of laudanum after delivery is a very 
common practice among midwives. 

Haemorrhoids. — When this disorder is associated 
with hard stools and reflex (ovarian) irritation, a single 
pill taken at night will often produce very favorable 
results. 



142 



THE POCKET PHARMACY. 



Headache. — Is rarely required in this disorder, 
except as an adjuvant to other treatment. It may 
occasionally favor sleep in bilious patients when they 
consult the physician late in the day, but is inferior to 
the alterative pill heretofore described. 

Heart, Dilated. — Is of value to calm excitement, 
although in a large percentage of the cases seen, code- 
ine sulphate or cannabis indica can be substituted 
with advantage. 

Heart, Valvular Disease of the.— Will prove 
useful to relieve the pain and dyspnoea, alone or in 
combination with atropine sulphate ; a dose of each is 
given every two hours. 

Hiccough. — Given only in alternation with atro- 
pine sulphate ; in very persistent cases this combina- 
tion will be required by hypodermatic injection to pro- 
cure sleep. 

Insomnia. — Is a dangerous remedy for young sub- 
jects, even during the progress of serious disease, but 
may be given cautiously to elderly persons in combina- 
tion with atropine sulphate. A dose of the morphine 
is taken every ten minutes for an hour, and one pill of 
atropine just before retiring. Codeine sulphate is pref- 
erable. 

Meningitis. — May be used alone, or with tartar 
emetic to quiet pain and produce what may be termed 
a revulsive effect. It should not be pushed, but may 
serve a valuable purpose in connection with bryonia 
and vascular sedatives, including the bromides and 
acetanilide compound. 

Nausea. — When this is due to reflex causes, mor- 
phine is sometimes available, but must be given in 
very small doses; a dose may be given at intervals of 
an hour. 



MORPHINE AND TARTAR EMETIC. 



143 



Pleurisy. — Allays the pain, but masks the disease. 
In very anaemic patients it can be used as a temporary 
expedient in combination with other remedies, but we 
should bear in mind that our object in the early stages 
of this disease is not so much to lessen the pain as to 
remove the cause, and this is best accomplished by re- 
ducing the activity of the circulation. 

Sciatica. — Morphine hypodermatically has been 
used successfully as a curative agent in sciatica, but is 
not now so generally employed, since acetanilide com- 
pound and rhus toxicodendron promise to take its place. 



MORPHINE HYDROCHLORATE AND 
TARTAR EMETIC. 

Each tablet, pill, or granule contains one-fiftieth 
grain of each medicament. 

Asthma. — This combination is sometimes of value 
in asthmatic conditions when capillary bronchitis 
threatens. A dose is given every ten minutes for an 
hour, then at intervals of one hour until relief is ob- 
tained. Arsenic sulphide and strychnine arseniate 
should follow to prevent relapse. Apomorphine may 
occasionally take the place of the combination recom- 
mended, but it is very depressing, and it would be well 
in these cases to bear in mind the value of substantial 
doses of quinine in asthmatic conditions. In cases of 
so-called humid asthma, which occur from slight ex- 
posure, the combination can be given for a period of 
twenty-four hours along with quinine hydrochlorate, 
and followed by euphorbia pilulifera alone or in com- 
bination with terebene or terpin hydrate. 

Bronchitis. — Is occasionally of benefit when the 



I 4 4 THE P0CKET PHARMACY. 

bronchioles are dry, with a constant cough and great 
restlessness with more or less pain or sense of oppres- 
sion in the chest. It is here that we may distinguish the 
approach of capillary bronchitis ; it is here also that 
we witness such signal benefits from the exhibition of 
arsenical preparations after the progress of the disease 
has been arrested t If the temperature and pulse-rate 
can be reduced, much benefit will be derived from the 
use of morphine and tartar emetic, as the pain is sub- 
dued, while the anodyne effect is not sufficient to inter- 
fere with the action of the tartar emetic in favoring 
the expulsion of accumulated mucus. Still, owing to 
the depression which it causes, by the extra work 
thrown upon the pulmonary structures, it is a plan 
which at best is of doubtful utility. The objects of 
treatment may be limited to the reduction of tempera- 
ture and pulse-rate and arrest of the profuse secretion, 
and it does seem that this could be accomplished with- 
out bringing so many remedies to bear upon the pul- 
monary structures with a view to increase the tax upon 
them. 

Pilocarpine hydrochlorate, one one-fiftieth grain 
every hour or two, is sufficient to increase bronchial 
secretion and quiet cough when due to arrested secre- 
tions, and there is no increased pulse-rate ; but apomor- 
phine has been highly lauded in just such cases as here 
described. When the latter is given, the dose should 
be small and repeated at short intervals, as in ordinary 
cases emesis is not desired. 

Catarrh, Acute Nasal. — Sometimes useful when 
the secretion seems thick and abundant, although it is 
principally indicated when the affection threatens to 
attack the bronchi ; a dose is taken every hour or two 
in combination with quinine hydrochlorate. 



MORPHINE AND TARTAR EMETIC. 



145 



Delirium. — Very efficient when it is desired to pro- 
duce sufficient nausea to modify the vaso-motor sys- 
tem ; a dose is given every hour until the desired effect 
is secured. 

Delirium Tremens. — May be used occasionally 
to quiet maniacal excitement and favor elimination by 
the skin and bowels. The water must not be allowed 
to accumulate in the bladder, and salines will be indi- 
cated unless the bowels are relieved. A pill can be 
given every ten minutes for one hour, then at less 
frequent intervals. Preparations of opium should be 
given with caution, because they derange digestion, 
and when pushed to narcotism the real condition of 
the patient may be obscured. Along with this method 
of treatment, camphor will be useful for its influence 
upon the nervous system. 

Hepatitis. — Adapted to the very painful cases in 
which we desire the effect of antimony ; a dose is taken 
every hour or oftener. 

Hysteria. — Is sometimes given with a view to pro- 
duce a revulsive effect in such cases ; for instance, as 
musk, asafcetida, and valerian are employed. 

Influenza. — Is of value in allaying pain, and pro- 
duces a favorable change when the condition of the 
bronchioles threatens to interfere with respiration ; a 
dose is taken every hour, alone or in combination with 
quinine hydrochlorate. 

Insomnia. — An excellent combination when there 
is a tendency to congestions of the brain or pulmonary 
apparatus ; a pill is taken every half-hour for several 
hours. 

Mania. — Used as a temporary expedient in acute 
cases for its calmative and revulsive effect ; a dose 
every hour or two. 

10 



I 4 6 THE POCKET PHARMACY. 

Pneumonia. — Indicated when the disease shows a 
disposition to affect the function of the smaller bronchi ; 
a dose is given every ten minutes for an hour along 
with oxygen inhalations. 

Puerperal Mania.— May be used in mild cases 
for several days with good results, but should not be 
depended upon as curative. 

Typhoid Fever. — Is indicated in low conditions 
of the system when hypostatic congestion is threat- 
ened. Morphine alone is sometimes of signal service 
in procuring sleep, although the bromides are gener- 
ally to be preferred. Wakefulness is often due to 
non-elimination or lack of food, consequently excre- 
tion must be carefully watched and medication con- 
ducted with a view to maintain the integrity of the 
digestive apparatus, else convalescence will be unduly 
prolonged. 

QUININE HYDROCHLORATE. 

Each tablet, pill, or granule contains one-fourth 
grain of the drug. 

After-pains. — Quinine is a valuable remedy in 
those cases where we have indications of failure on the 
part of the eliminative functions, as the skin, kidneys, 
and bowels, and where the general circulation is slug- 
gish. Quinine in appropriate dosage increases arterial 
tension, and stimulates the hepatic and renal func- 
tions ; under its influence the skin becomes more 
active, while the tonicity of the uterine muscle and 
nerve-supply is materially enhanced. In the majority 
of cases it is far superior to ergot ; a dose is given 
every ten or fifteen minutes for an hour, then every 
half-hour until the desired effect is secured. 



QUININE HYDROCIILORATE. I47 

Alcoholism. — It enacts the role of a cerebral seda- 
tive in the case of " horrors," an aid to digestion, and 
indirectly a liver stimulant. It will be found useful in 
the form of the arseniate at the expiration of twenty- 
four hours, but a full dose of the hydrochlorate (five 
or ten grains) should be given at once. 

Anaemia. — Quinine is always demanded at certain 
stages in the treatment of anaemia. In connection 
with the employment of alteratives (see Mercury Bin- 
iodide), it appears to exercise a beneficial influence upon 
the circulation, favoring a more perfect distribution of 
the blood, not to mention its effect upon the hepatic 
cells. And, again, when combined with iron, whether 
or not we accept Metschnikoff's theory of phagocyto- 
sis, we know that it has a powerful effect in overcom- 
ing malnutrition; but it must not be given in large 
doses, nor long continued. 

Angina Pectoris. — Useful after the subsidence of 
the attack to remove any malarial influence which may 
be present. 

Aphthae. — Aphthae in children may be dependent 
upon malarial infection, and, in addition to copper ar- 
senite, quinine will be required ; a child two years of 
age will take a pill every two hours during the day. 

Asthma. — Taken during the intervals between the 
attacks of spasmodic asthma, quinine will assist ma- 
terially in restoring the vaso-motor tension in the pul- 
monary capillaries, and along with other treatment 
will postpone or avert future attacks. An adult can 
take six grains daily with much benefit. 

Atheroma. — Given in small doses, it is a valuable 
adjunct to arsenic in the treatment of atheromatous 
changes with cerebral manifestations. 

Bronchiectasis. — Exercises an important influence 



I4 8 THE POCKET PHARMACY. 

in this affection ; its use should be conjoined with crea- 
sote and terebene, or for delicate subjects terpin hy- 
drate should replace terebene; one or two pills are 
taken every two hours. 

Bronchitis. — Useful as an antipyretic and vascular 
tonic ; after the active stage has passed it can be com- 
bined with creasote in pill-form to advantage. 

Carbuncle. — Is given alone or preferably in com- 
bination with calcium sulphide for its general tonic 
and antiseptic properties. It has no real value as an 
antipyretic to control fever in this disease, but the 
temperature may be controlled by the judicious em- 
ployment of the biniodide and avoidance of poultices; 
elimination rather than antipyresis should be our 
motto. 

Catarrh, Acute Nasal. — A pill should be taken 
every hour during the first stage, along with gelse- 
mium. 

Cerebral Anaemia. — An excellent vascular tonic 
in cerebral anaemia ; a dose is taken every hour or two. 

Chlorosis. — Is given in this disorder in alternation 
with iron arseniate ; a pill is taken every three hours 
along with a pill containing one grain of pure beech- 
wood creasote. Diet and salines must receive due con- 
sideration. 

Cholera, Asiatic. — An excellent vascular tonic; 
given in small doses at short intervals in this disorder, 
it would seem as though it might have some influence 
upon phagocytosis and upon the hepatic function. 

Chorea. — Often demanded in anaemic conditions 
along with iron arseniate ; a pill is given every two or 
three hours for three days, then omitted for the same 
length of time, to be renewed. 

Croup. — Probably the best remedy in the spas- 



QUININE HYDROCHLORATE. I49 

modic variety of croup. A child two years of age can 
take a pill every ten minutes for an hour, when all 
trouble will probably subside, and the patient imme- 
diately fall asleep. A child five years of age can take 
two grains, to be repeated, if necessary, in the course of 
half an hour. 

Cystitis. — Is used in acute attacks in combination 
with aconite ; a dose is taken every ten minutes for an 
hour, then at intervals of one hour. 

Deafness. — Is said to be useful in Meniere's dis- 
ease ; substantial doses cause ringing in the ears, an 
evidence of congestion, a fact which may be utilized 
when we desire to increase the local blood-supply, but 
this effect must not be too long continued, else it will 
increase the deafness by setting up a catarrhal con- 
dition. 

Debility. — A most efficient general tonic in de- 
bility, rivaling strychnine in its extended range of 
application. A combination of the two medicaments 
will often produce the most salutary effects, provided 
nutrition is favored by appropriate aliment. There 
are many instances in which a small dose is better 
borne by the patient than a large dose, owing to the 
debilitated condition of the system. A pill is taken 
every hour or two for two or three days, then omitted 
for a like interval, again to be renewed. 

Delirium. — Useful when dependent upon derange- 
ment of vaso-motor tension, and we wish to avoid ano- 
dynes and narcotics ; a dose may be given hourly. 

Delirium Tremens. — As soon as the effect of the 
whisky begins to disappear, quinine should be used 
as an aid to strychnine arseniate in the readjustment 
of vascular tension. It also aids digestion, and favors 
elimination ; a dose is taken every hour. 



i5o 



THE POCKET PHARMACY. 



Diabetes Mellitus. — Will be found useful given in 
combination with iron arseniate ; a dose is taken every 
two hours. Diet is of importance, but does not come 
within the limits of this work. 

Diarrhoea. — A specific in that form occurring as a 
result of malarial toxaemia, along with small doses of 
podophyllum or of the biniodide, according to the 
special indications. Substantial doses are required, 
preferably in the early morning 

Diphtheria. — Is one of our most valuable consti- 
tutional remedies, but has no specific action further 
than that of maintaining a favorable condition of the 
normal functions. In case the synthetic antipyretics 
are used, it should be employed at short intervals in 
small doses for its influence upon the heart and vas- 
cular system. 

Dyspepsia. — Is of value in that form of dyspepsia 
from which elderly persons suffer, sometimes called 
" wind dyspepsia " One or two pills are taken every 
two hours, along with a dose of copper arsenite in hot 
water half an hour before meals. The latter may be 
discontinued except before breakfast as soon as im- 
provement is noticed, but an occasional saline is of 
great utility, 

Dysuria. — Quinine should be given in substantial 
doses when dysuria results from exposure to cold ; two 
pills are taken every half-hour until ten doses are 
taken. A hot sitz-bath night and morning completes 
the treatment. 

Ecthyma. — A dose is taken every two hours, along 
with the biniodide every four hours, attention being 
given to local treatment diet, and hygiene. 

Empyema. — Quinine is a remedy whose well- 
known properties as a blood-tonic recommend it, al- 



QUININE HYDROCHLORATE. jj! 

though surgical measures are demanded. The initial 
dose should be large, after which the system can be 
kept under its influence by small doses at short inter- 
vals. 

Endocarditis. — The simple form should have fair- 
ly large doses, say two pills every hour ; rheumatic 
cases require salicylates or alkalies. 

Endometritis. — Is almost a necessity in this dis- 
ease, but not necessarily in large doses. A pill can be 
taken every two hours along with calcium sulphide, 
but of course this can not be expected to take the 
place of local treatment. Ergot should be added in 
case subinvolution is marked. 

Epilepsy. — May be demanded from time to time 
for the relief of intercurrent complications, malaria, 
biliousness anaemia, etc., but it has no direct influence 
upon the disease. 

Erysipelas. — The initial dose should be large, in 
order to bring the system immediately under its influ- 
ence ; smaller doses should then be given at short 
intervals. Local antiseptic treatment should be 
adopted. 

Erythema. — Useful in erythema nodosum, prob- 
ably through its general action upon nutrition. 

Fever. — Many physicians will find it difficult to 
reconcile the two methods of administering quinine, 
hence a word in explanation is offered in connection 
with its employment in the treatment of fevers — mala- 
rial, typhoid, and that due to septic conditions of the 
system. In all of the above-named diseases it will be 
readily admitted that the elevation of temperature and 
rise in pulse are due to the presence of germs or their 
products. In malaria, the micro-organism may be dis- 
covered in the blood ; the typhoid germ finds a suit- 



152 THE POCKET PHARMACY. 

able soil for its development in the glands of the small 
intestine and omentum ; the germs which contribute to 
produce septic conditions of the system and fever are 
now very generally recognized, but physicians have 
been less successful in their warfare against these me- 
phitic influences than our brethren in the domain of 
surgery. The acid secretions of the stomach are 
known to have a deleterious effect upon these germs, 
but few of them are exposed to this influence; the 
blood-serum possesses antiseptic properties, and doubt- 
less, under normal conditions, aids materially in pre- 
venting a more rapid multiplication of micro-organisms ; 
the kidneys, the bowels, and the skin, not to mention 
phagocytosis, also exercise important functions in elimi- 
nating from the system poisonous products, but no 
organ or function is of greater importance in this war- 
fare than the liver. This organ is seriously disturbed 
in malaria ; in typhoid fever the portal system carries 
the blood loaded with poison directly to it ; and prac- 
tically this is the case in all septic conditions, because 
the hepatic circulation includes the entire circulatory 
system. In grave diseases, therefore, when we desire 
the specific effect of quinine, which may be either the 
antiperiodic or antipyretic action, substantial doses are 
required. It is necessary that the remedy be thor- 
oughly distributed over the whole system, and de- 
posited in the liver in sufficient quantity to either 
destroy the poison or stimulate the hepatic cells in 
such a manner that they will be able to accomplish 
more in this direction than is possible during the prog- 
ress of disease. Whether or not it has any specific 
effect upon the hepatic cells, which enables them to 
functionate more perfectly, is a question still unsettled; 
there is ample evidence, however, that it does have a 



QUININE HYDROCIILORATE. 153 

stimulant action upon the liver, as shown by increased 
output of bile and other unmistakable evidences. 

We are now in a position to understand what might 
with propriety be called the relative value of quinine 
from a clinical standpoint, as contrasted with its spe- 
cific value; and we can, without any stretch of the 
imagination, conceive of functional changes in the 
economy which would be perfectly covered by small 
or tonic doses. Upon the character and stage of the 
disease, therefore, will depend our decision regarding 
the aggregate amount of the remedy to be exhibited 
at a single dose, and the amount to be given during 
the period of twenty-four hours, always making due 
allowance for idiosyncrasies. 

Gastralgia. — Is employed here as an antiperiodic 
in malarial toxaemia; it is used in small doses when 
dependent upon debility, say a dose every two hours, 
along with an occasional dose of the biniodide. Sodium 
salicylate will be required in rheumatic cases. 

Gonorrhoea. — Adapted to the later stages as a 
tonic; a dose every two hours. Along with this, when 
any symptoms remain, the balsam of copaiba or sandal- 
wood oil will sometimes afford striking benefit. 

Gout. — Is given in tonic doses for its stimulant 
effect in debilitated subjects, either alone or in combi- 
nation with iron arseniate ; a pill every hour or two. 

Hay-fever. — Useful in substantial doses along 
with the local employment of a solution of copper ar- 
senite. The successful treatment of a number of cases 
of this character by the plan recommended is the best 
evidence of its ability to cut short the disease. 

Hematuria. — Indicated when a malarial element 
exists; a substantial initial dose is given, followed by 
smaller doses until checked. 



154 THE POCKET PHARMACY. 

Haemorrhage, Post-partum.— In a single large 
dose is a powerful oxytoxic. In the absence of other 
remedies six to ten grains may be given in solution, 
though not all at once, in case we wish to avoid 
nausea. 

Headache. — Applicable in malarial toxaemia ; the 
condition of the bowels is investigated, and substantial 
doses given. Anaemic headaches respond readily to 
tonic doses; a pill every hour. 

Hectic. — Useful as an antiseptic ; the whole amount 
should be given during the early morning hours, alone 
or in combination with acetanilide compound. Qui- 
nine in moderate dosage counteracts the depression 
following the use of the latter. 

Hiccough. — Must be given in antiperiodic doses 
to have any beneficial action. 

Inflammation. — Very effective in all low condi- 
tions of the system along with other indicated reme- 
dies ; a large initial dose should be followed by smaller 
doses at short intervals. 

Influenza. — Useful in the beginning in moderate 
dosage after the exhibition of aconite or gelsemium, 
and during the later stages to hasten recovery ; it 
may be taken in combination with calcium compound 
— a dose of each every hour. 

Intermittent Fever. — Quinine may be accepted 
as a specific in the treatment of this disease. The 
regular succession of chills can certainly be arrested 
by attention to preliminary details, and the exhibition 
of a sufficient quantity of the drug at the right time. 
In this country small doses (comparatively) are re- 
quired in the Northern sections, larger doses in the 
middle section, while very large doses are required in 
the South. The probabilities are that the require- 



QUININE IIYDROCHLORATE. 155 

ments in different portions of the United States repre- 
sent substantially the conditions which obtain else- 
where, as there can be no further doubt that the disease 
is represented by a specific entity in the form of a 
micro-organism. 

With this knowledge in our possession, we give 
quinine with a degree of certainty which is comforting 
in the extreme. The preliminary details embrace a 
consideration of the patient's physical condition — the 
vis medicatrix naturce. The derangement of function 
which has led to the development of the disorder must 
also be weighed, and whatever can be done to restore 
normal functions should be undertaken with the idea 
of accomplishing it at as little expense as possible to 
the physical strength. The time for administering the 
drug will be decided according to the gravity of the 
disease ; in ordinary cases we may wait for a subsi- 
dence of the periodic elevation of temperature and 
pulse-rate. Frequently, however, this favorable period 
may be brought about by the employment of vascular 
sedatives and hepatic stimulants; and, as a rule, the 
system will be found most susceptible during the early 
morning hours. An adult should have at least ten 
grains at once in solution or in capsules containing a 
readily soluble salt, and in two to four hours five or 
ten grains more in the same manner. Bromides can 
be given to allay cerebral irritation. Rather smaller 
doses should be given on two successive mornings, and 
the initial dose repeated on the approach of the sep- 
tenary period. 

In tropical and subtropical countries, where the 
seizures are ushered in by congestive chills, the hypo- 
dermatic method must be adopted, using fifty per cent 
larger doses than indicated above, in which case it is 



^6 THE POCKET PHARMACY. 

claimed there is no need for considering the return of 
septenary periods, as is the case when the medicine is 
administered internally. Prophylactic measures include 
the employment of tonic doses, hepatic stimulants, sa- 
lines, and nervines. 

Jaundice. — Best adapted to the malarial cases; a 
substantial dose is given every morning after breakfast, 
the colon to be flushed with cold or tepid water daily. 

Lumbago. — Useful in connection with rhus toxi- 
codendron to abort an attack; it is also of value in 
overcoming the depression following an attack ; a dose 
every two hours. 

Measles. — Used in tonic doses after aconite and 
gelsemium to prevent pulmonary congestions and favor 
elimination. Pilocarpine hydrochlorate is useful in 
combination with quinine when the skin is dry, and 
there is no marked rapidity of the pulse. A child five 
years of age can take a dose of quinine and one one- 
fiftieth grain of pilocarpine hydrochlorate every two 
hours. 

Meniere's Disease. — Adapted to the debilitated 
and overworked ; two pills are taken every hour. 

Meningitis, Cerebral. — Not indicated in the early 
stage, but during the later period and convalescence 
it will assist materially in rehabilitating the system. 

Menorrhagia. — Often most valuable, alone or in 
combination with a daily dose of ergot ; a pill is taken 
every hour or two. 

Neuralgia. — A necessity in periodical cases, alone 
or in conjunction with the biniodide ; a pill is taken 
every ten minutes for an hour, then at intervals of an 
hour, with a dose of the biniodide at night on retiring. 

Nyctalopia. — Has been recommended in large 
doses for the relief of this disease. 



QUININE HYDROCHLORATE. ^7 

Pericarditis. — Useful to act as an antiseptic upon 
the blood; a dose is given every ten minutes for an 
hour, then at intervals of one hour, the patient being 
instructed to retain the recumbent posture. 

Peritonitis. — Very important for its antiseptic 
action upon the blood, although it is not necessary to 
produce cinchonism unless there be a malarial element 
present. 

Perspiration. — When occurring from debility in 
phthisis, tonic doses are valuable ; a pill is taken every 
hour during the day. 

Pertussis. — A remedy of decided value in modify- 
ing the spasmodic element in this disease ; it has also 
a favorable influence upon the bronchial and pulmonary 
mucous membranes. In connection with the adminis- 
tration of quinine, inhalations of oxygen gas or of hy- 
drogen dioxide are of marked efficiency. A child six 
or eight years of age can take six to eight grains of 
quinine hydrochlorate daily along with six to ten gal- 
lons of pure oxygen gas. When the cough is dry, pilo- 
carpine hydrochlorate (gr. x / 50 ) should be given every 
two hours, and, later in the disease, calcium sul- 
phide. 

Pharyngitis. — Useful in debilitated subjects, alone 
or in combination with strychnine arseniate ; a dose of 
each every two or three hours. 

Phthisis. — Is employed as a tonic antipyretic, and 
for its anhydrotic properties. A meat diet, or a diet 
principally of bread and meat, produces remarkable re- 
sults in many cases. 

Pleurisy. — Should be used for its antipyretic and 
antiseptic action, but not to the extent of producing 
cinchonism. In connection with other treatment indi- 
cated, salines may be required. 



I5 8 THE POCKET PHARMACY. 

Pleurodynia. — When associated with malarial tox- 
aemia or a debilitated condition of the system, quinine 
is indicated ; the chest should be strapped and a dose 
given every hour. 

Pneumonia. — Useful for its antipyretic and anti- 
septic action, after temperature and arterial tension 
have been subdued by the exhibition of vascular seda- 
tives. The question of giving a single large dose or 
several small doses in quick succession is one which 
will be decided by the physician, who should be gov- 
erned by the susceptibility of the patient, the period 
and gravity of the disease. The employment of anti- 
pyretics for their specific effect is a practice of doubt- 
ful utility during the prevalence of epidemics. 

Puerperal Fever. — Must be given in substantial 
doses in addition to appropriate local measures, and 
the free use of salines. 

Puerperal Mania. — Very useful when there is a 
disordered condition of the digestive apparatus, in 
which case it should be given along with cannabis 
indica. 

Purpura. — Is employed to improve the digestive 
functions and give tone to the vascular system. Strych- 
nine arseniate or calcium sulphide should be added in 
accordance with the symptoms present. 

Pyaemia. — Should be given in substantial doses to 
the point of cinchonism, alone or in alternation with 
sodium salicylate or other suitable antiseptic. 

Pyrosis. — Indicated when associated with malaria ; 
a dose every hour or two. 

Rheumatism, Acute.— Is used as an antipyretic 
in substantial doses, alone or with salol or sodium sali- 
cylate. When appearing without marked constitutional 
disturbance — absence of high temperature and lack of 



QUININE HYDROCHLORATE. 159 

appetite — rhus toxicodendron added to quinine hydro- 
chlorate will be sufficient to arrest the disorder. 

Rheumatism, Chronic. — Will be useful when the 
patient is much depressed, given in tonic doses, alone 
or with iron arseniate. In case the tendons or sheaths 
of muscles are most affected, rhus toxicodendron will 
be efficacious. 

Rheumatoid Arthritis.— In the form of the sali- 
cylate, it will serve a useful purpose, alone or in com- 
bination with iron arseniate. 

Scarlet Fever. — Should be given for its antiseptic 
action and general antipyretic properties. The influ- 
ence of quinine upon the vaso-motor system would in- 
dicate its employment when there is great depression. 
It may be alternated with sodium salicylate, or quinine 
salicylate may be employed instead. 

Scurvy. — Is of decided value alone or in combina- 
tion with ergot, although they should not be given 
continuously. 

Spermatorrhoea. — An excellent general tonic in 
many cases, but only moderate dosage is required ; a 
pill is given every two hours in connection with other 
medication when indicated. 

Splenic Affections. — Along with ergot in hyper- 
trophy associated with malaria, quinine is almost spe- 
cific, but substantial doses must be given, as in the 
treatment of intermittent fever. 

Sunstroke. — Adapted to the after-treatment of 
thermic fever for its general tonic effect. 

Suppuration. — In all cases it may be said quinine 
is indicated. Its administration produces better re- 
sults in many cases when given in combination with 
calcium sulphide, but the two medicaments should not 
be made up in pill form together. In the treatment of 



x 6o the pocket pharmacy. 

suppuration a dose of each may be given at intervals 
of an hour or two. 

Tetanus. — Has been used in both idiopathic and 
traumatic tetanus with apparent benefit, although this 
result must be accredited rather to its indirect effect 
upon the liver than to its direct influence upon the 
tetanus poison, recent demonstrations having shown 
that the tetanus poison accumulates in the liver to the 
exclusion of the blood, the cerebral and spinal tissues, 
and the vital organs. 

Tonsillitis. — Small doses are of value to meet the 
depression following an attack. Occasionally this dis- 
ease will be found associated with other disorders — ma- 
laria, rheumatism, etc. — in which case the indications 
point to the employment of quinine or the salicylates. 

Toothache. — A full dose will usually abort tooth- 
ache incident to exposure, but in many cases it will be 
necessary to follow this with a few doses of calcium 
sulphide to prevent the formation of abscess. 

Typhoid Fever. — Is given in tonic doses for its 
influence upon the vascular system, the liver, and as a 
nervine. Undoubtedly it exerts a good effect upon 
the blood, but cinchonism is unnecessary unless there 
be a malarial complication present, when it must be 
treated on the same general plan as intermittents. 

Typhus Fever. — Useful for its antiseptic proper- 
ties, which lessens the fever and modifies the character 
of the disease ; a dose of five or more grains should be 
given morning and noon, alone or in combination with 
phosphoric acid well diluted. 



RHUS TOXICODENDRON. 161 



RHUS TOXICODENDRON. 

Each tablet, pill, or granule contains one half 7nini?n 
of the tincture prepared from the leaves according to the 
directions given in the United States Pharmacopoeia 
for making green tinctures. The leaves should be 
gathered during the period of efflorescence, preferably 
in the early morning, and from plants growing in the 
shade, as it is believed that under these conditions a 
larger portion of toxicodendric acid, the active princi- 
ple, is obtained. This active principle is exceedingly 
volatile, and is practically dissipated in drying, for 
which reason preparations made from the dried leaves 
are valueless. The remedy was employed in both 
France and England as early as 1798, and was official 
in the British Pharmacopoeia in 1836. During the past 
ten years its properties have been studied by Phillips, 
of England, and Piffard, of New York, so that it is not 
a remedy which in any sense belongs to so-called 
homoeopathic practice. 

Cachexia. — Rhus toxicodendron is a useful rem- 
edy in rheumatic cachexia; a dose is taken every two 
or three hours, the pill being allowed to dissolve in 
the mouth. 

Cerebral Anaemia. — A valuable stimulant in low 
conditions of the system, with nervous manifestations; 
a dose is taken every hour or two. 

Cystitis. — Very useful in chronic cases, with a tend- 
ency to retention ; a dose is taken every three or four 
hours. May be alternated with Saw palmetto in pros- 
tatic enlargement occurring in elderly persons. 

Earache. — Applicable in those cases with a rheu- 
matic history, or even symptoms of a rheumatic tend- 
11 



1 62 THE POCKET PHARMACY. 

ency on exposure to cold. These patients are usually 
underfed, overworked, and poorly clad. A pill is dis- 
solved in the mouth every hour for several hours, and, 
commencing on the next day, a dose is taken three 
times a day. 

Eczema. — Adapted to both acute and chronic 
cases, and where we have any history or symptoms of 
rheumatism the indications are very positive. Add to 
this the nervous manifestations, and the symptomatol- 
ogy is complete. Burning and itching are the most 
characteristic symptoms. A dose is taken every three 
or four hours, and salines advocated to alkalinize the 
blood. Weak solutions may be applied locally, but 
this must be executed with care in susceptible patients. 

Enuresis. — Adapted to the cases with marked 
acidity of the urine, but light suppers must be insisted 
upon and fruits avoided during the latter portion of 
the day. A child five years of age can take a dose 
every four hours for several days. 

Epilepsy. — Used to relieve the muscular soreness 
after an attack, and is especially adapted to rheumatic 
cases, although it is useful in all. 

Erysipelas. — Indicated in the early stage of the 
disease, when the skin is hot and dry ; it is best suited 
to neurotic patients, and may not produce any apparent 
effect upon persons not susceptible to the poison, for 
which due allowance must be made. 

Erythema. — An efficient remedy in this class of 
cases ; the small doses are readily taken by children, 
and the effects promptly appear ; a pill is dissolved in 
the mouth every three or four hours. 

Fever. — This remedy is most efficient when we 
have to deal with fevers preceded or accompanied by 
rheumatic symptoms, either frank or masked. Of 



RHUS TOXICODENDRON; 163 

course it is used in rheumatic fever, although not in 
all cases, and when it fails to produce the expected 
effect we may conclude that the preparation is faulty 
or that the patient is not susceptible to the poison. It 
is best adapted to the cases in which the burden of 
complaint is from pain in the tendons and fasciae, indi- 
cated by excruciating pain when movements are at- 
tempted. Symptoms also occur in typhoid and scarlet 
fever indicating the exhibition of rhus toxicodendron, 
and in these cases prompt results follow its administra- 
tion. A dose is taken every hour or two dissolved in 
the mouth. 

Gastralgia. — Suited to cases having a rheumatic 
history, and may be given along with other medication 
that is not calculated to destroy its virtues ; a dose is 
taken every hour or two for the emergency. 

Haemorrhoids. — Allays the pain, and produces a 
favorable effect when associated with a rheumatic his- 
tory. The biniodide is a useful adjunct to insure per- 
manency. A dose of rhus is taken three times a day. 

Headache. — Is adapted to that variety of head- 
ache due to a rheumatic diathesis, often following ex- 
posure to cold, and accompanied by acid eructations ; 
a pill is given every hour at first, then at less frequent 
intervals. 

Heart, Fatty. — Is of service when there is a rheu- 
matic complication present ; a dose every three or four 
hours. 

Herpes Zoster. — As this disorder appears many 
times in connection with a rheumatic diathesis, we 
might expect favorable results from the internal ad- 
ministration of rhus, together with its local application ; 
a dose is taken every hour or two, and the affected 
area bathed with a weak solution of the remedy. 



164 THE POCKET PHARMACY. 

Inflammation. — A most efficient remedy in rheu- 
matic patients, alone or in combination with atropine 
when the throat is affected ; a pill is dissolved in the 
mouth every hour or two. 

Influenza. — Useful to relieve the joint-pains occur- 
ring toward the end of an attack in rheumatic patients ; 
a dose every two hours. 

Locomotor Ataxia. — Will relieve the pain and 
stiffness of the smaller joints, where we have to deal 
with symptoms of rheumatoid arthritis. It has also at 
first a favorable influence upon the fulgurating pains 
affecting the extremities, but this soon disappears. A 
dose every two hours will relieve the stiffness and pain 
in the smaller joints very considerably, and allow the 
patient to have a good night's rest. 

Lumbago. — Useful in recent cases of the rheu- 
matic type, and along with quinine to abort an attack 
when faradization is not practicable or convenient ; a 
dose is taken every two hours. 

Mastitis. — Useful in rheumatic patients along with 
calcium sulphide; a dose of each every two hours. 

Myalgia. — When the pain is in the muscle sub- 
stance, indicated by attempts to move producing 
twinges, rhus is an excellent remedy ; a dose is taken 
every two or three hours. 

Neuralgia. — When of rheumatic origin, this rem- 
edy will often relieve promptly ; a pill is dissolved in 
the mouth every hour. 

Pharyngitis. — Very effective in rheumatic pa- 
tients; a pill is dissolved in the mouth every two or 
three hours. In very chronic cases the spray of perox- 
ide of hydrogen (Marchand's), or a solution of copper 
arsenite, should be added to the treatment. 

Pleurodynia. — Depending upon the character of 



RHUS TOXICODENDRON. 165 

the pain, it will usually respond to rhus or bryonia. 
In case the pain is constant, but more noticeable dur- 
ing inspiration, they should be given in alternation ; a 
dose of each every two hours. 

Purpura. — The knowledge that rhus has a tendency 
to produce rapid changes in the cutaneous system 
might be utilized in the treatment of this disease. 
Its employment in conjunction with quinine is sug- 
gested. 

Rheumatism, Acute. — Especially indicated in the 
later stages of the acute cases, and in subacute and 
chronic cases. Where the acute symptoms are not 
ushered in with marked constitutional disturbances, 
the rhus may be given in combination with quinine to 
abort the attack ; a dose is given every two or three 
hours. The employment of quinine and the salicylates 
is not contra-indicated when this remedy is used, but 
their use is often rendered unnecessary. 

Rheumatism, Chronic. — A very useful remedy 
given in small doses ; a pill is dissolved in the mouth 
three or four times a day. It is especially indicated 
when the tendons and sheaths of muscles are affected, 
which is manifested bv pain on movement. A solu- 
tion may be used locally as a stimulating embro- 
cation. 

Rheumatoid Arthritis. — Unless the cases are 
very far advanced, small doses will enable patients to 
use hitherto useless joints with comparative freedom, 
barring sudden changes in the weather ; a dose is taken 
every two, three, or four hours. 

Scarlet Fever. — Is indicated for various con- 
ditions ; when the skin is dry and harsh, the kidneys 
inactive, or the tongue red and inflamed, it will afford 
great relief. 



!66 the pocket pharmacy. 

Sciatica. — Indicated in a large proportion of the 
cases, where the mischief is situated in the nerve-sheath, 
shown by pain on motion. It may be alternated with 
bryonia when the pain is constant, an indication that 
the inflammatory action has extended to the synovial 
membrane. 

Sprains. — Valuable when a rheumatic history ex- 
ists. It may be given internally, a dose every hour or 
two, and a weak solution of the tincture applied locally, 
although the clay dressing produces more prompt ef- 
fects, and at the same time serves the purpose of a 
bandage. 

Tonsillitis. — When associated with rheumatism, 
rhus affords prompt relief; a dose is taken every hour 
or two. When the patient complains much of sore 
throat, atropine should be added. Occasionally this 
treatment fails where indicated by reason of the system 
being surcharged with the poisons incident to non- 
elimination, when resort must be had to the salicylates. 
It should be mentioned here that, as a rule, local appli- 
cations are not only useless, but, as generally applied, 
are positively harmful, and everything of this nature 
except dry heat must be interdicted. 

Typhoid Fever. — A very useful remedy when the 
kidneys are inactive, with highly acid urine, or when 
rheumatism or joint-pains occur during the later period 
of the disease and convalescence. It is especially in- 
dicated for the neuralgias, paralyses, and rheumatic 
symptoms, including sciatica, which manifest them- 
selves at the later stages of the disease and contribute 
materially to prolong convalescence. 



STROPHANTHUS. ^7 



STROPHANTHUS. 

Each tablet, pill, or granule contains the equivalent 
of two minims of the tincture of strophanthus. 

Albuminuria, Chronic. — In chronic albuminuria 
where elimination is hindered, caffeine, digitalis, or 
sparteine sulphate may be used with advantage, as 
strophanthus is not equally valuable in all cases. In 
contracted kidney the chloride of gold and sodium is 
indicated. In the earlier stages, before serious damage 
to the renal structures has taken place, pilocarpine 
hydrochlorate, by increasing the activity of the skin 
and mucous membranes, lessens the work of the kid- 
ney, and thus becomes an important factor in thera- 
peutics. 

Amaurosis. — Is especially valuable in the amau- 
rosis and cardiac depression due to nicotine poisoning; 
a pill is taken every three or four hours, and tobacco 
in all forms discontinued. 

Debility. — Indicated when cardiac action is feeble 
and circulation impaired. The addition of atropine 
and alcoholic stimulants may be required. 

Diphtheria. — May be given cautiously to meet car- 
diac weakness occurring in the course of the disease, 
or to counteract depression following the exhibition 
of antipyretics. 

Dropsy. — Is a very useful remedy in so-called 
cardiac dropsy, and may be given with benefit to 
elderly people where the cardiac contractions are 
imperfect. 

Fever. — Strophanthus is often of service in the 
cases where strychnine is indicated, but it is much 
more prompt than preparations of that remedy. Where 



1 68 THE POCKET PHARMACY. 

the cardiac muscle shows relaxation, as in phthisis, and 
in protracted cases of typhoid and lingering pneumonia, 
this remedy given cautiously will produce excellent 
effects; a dose every three or four hours. It may be 
allowed to take the place of strychnine arseniate for 
the emergency. Occasionally it will be advisable to 
combine it with a small portion of the tincture of digi- 
talis, say five drops in cases of simple oedema with 
lowered condition of the arterial tension. It is in this 
class of cases that arsenic is valuable, and strophan- 
tus may be combined with small doses of arsenic, say 
two drops of Fowler's solution along with a dose of 
strophanthus every four hours. 

Heart, Dilated. — A powerful cardiac tonic when 
used in small doses, but large doses destroy the func- 
tion of the motor ganglia and cause collapse. A pill 
is given three or four times a day with iron arseniate 
or arsenic alone. 

Hfeart, Valvular Disease of the.— Employed in 
small doses, strophanthus will sometimes produce ex- 
cellent effects. It is especially indicated in elderly 
persons when the cardiac contractions are incomplete; 
a dose three times a day. 

Pericarditis. — When the contractions are weak, it 
may be used along with bryonia, but only in small 
doses, the patient to maintain the recumbent posture. 
A dose is taken every four hours. 

Phthisis. — Often very useful to meet profound de- 
pression in this disease when the patient is very weak, 
and subject to " sinking spells." A few doses along 
with a little brandy or whisky will produce a marked 
change in a short time. 

Pneumonia. — Often renders important service in 
overcoming cardiac weakness at the crisis ; a dose is 



STRYCHNINE ARSENIATE. 169 

given every two or three hours, alone or combined 
with a small quantity of brandy or whisky. 

Typhoid Fever. — Indicated for the relief of great 
cardiac depression, alone or in combination with whis- 
ky. Good whisky and readily digestible, nutritious 
food, among which should be mentioned Wyeth's beef 
juice, are the only remedies which can be safely em- 
ployed with a liberal hand in typhoid fever. 



STRYCHNINE ARSENIATE. 

Each tablet, pill, or granule contains one one-hundredth 
grain of the drug. 

Alcoholism. — Strychnine is believed to be anti- 
dotal to the taste for liquor. It acts also as an aid to 
digestion, and is a valuable nervine, the addition of 
arsenic in the above form making the combination 
more useful and effective than the single remedy. It 
will be found in practice that small doses at short in- 
tervals produce the best results, and, besides, we avoid 
the dangers of cumulative action. Opium and cocaine 
are always contra-indicated, but collateral symptoms 
may be met by the exhibition of cannibis indica, cap- 
sicum, quinine, copper arsenite, mercury biniodide, 
bromides, chloralamid, with or without strophanthus, 
and salines as required. Ripe apples eaten between 
meals possess a high degree of utility in creating a dis- 
like for alcohol, probably because they supply nature's 
laboratory with certain materials adapted to supply a 
systemic want that alcohol temporarily furnishes. 

Amaurosis and Amblyopia. — A most efficient 
remedy when due to tobacco or alcoholic excesses, but 
must be used with caution where cranial disease exists. 



170 



THE POCKET PHARMACY. 



It may be used with advantage in combination with 
pilocarpine hydrochlorate ; a dose is taken every four 
hours. 

Anaemia. — Is useful in connection with iron arse- 
niate in the treatment of anaemia, but small doses 
should be given, say a pill three or four times a day. 
Not infrequently it may be combined with the digestive 
ferments. 

Angina Pectoris. — This remedy is occasionally 
of value in angina pectoris, more especially the attacks 
which are associated with physical exhaustion ; a dose 
is taken every hour or two for several hours. During 
the interval it may be continued with iron arseniate . 

Appetite, LOSS of. — Strychnine with an acid is 
useful in loss of appetite with nervous manifestations, 
but when using the combination selected, it will be 
found effective without an acid. The tablet previously 
mentioned — viz., copper arsenite compound — is an ex- 
cellent combination for simple cases of this character, 
and is especially valuable in phthisis ; a pill dissolved 
in hot water is taken half an hour before eating. 

Asthma. — Strychnine arseniate is an effective 
stimulant of the respiratory apparatus, probably 
through its action upon the muscular structures in the 
heart and arteries ; but due allowance has not hereto- 
fore been made for the influence of strychnine upon 
the elastic fibers of the air-cells by which the resiliency 
of the cells is regained. In asthma the cells are dis- 
tended, the blood-vessels (capillaries), according to 
Flint, forming the greater portion of the cell-wall ; 
hence a slow or intermittent blood-stream will prac- 
tically arrest tissue metamorphosis. Depression fol- 
lows in direct ratio with the hindrance to the normal 
distribution of the blood. We have then a practical 



STRYCHNIN- /RXMATE. 



171 



illustration of the advantages to be gained from study- 
ing the influence of medication upon the cell ; it 
amounts to a demonstration of the utility of strych- 
nine in all disorders of the pulmonary apparatus, in 
which distention of the air-cells is the predominant 
factor. This effect I am disposed to attribute to the 
influence of strychnine upon the cells composing the 
elastic fibers, not direct, but through the medium of 
the nervous system. We must bear in mind, however, 
that substantial doses will shortly impair the capacity 
of muscle to perform a certain amount of work, as 
shown by increased capacity when the drug is discon- 
tinued. It is important, therefore, that the dose be so 
graduated that we shall secure the desired therapeuti- 
cal effect. The applicability of arsenic in asthma, em- 
physema, and other pulmonary affections admits of an 
equally satisfactory explanation, and for this reason 
a medicament combining the therapeutical virtues of 
both has been selected. In asthmatic conditions with 
emphysema, a dose should be given every two or three 
hours. 

Atrophy. — Is advantageous in atrophic conditions, 
along with copper arsenite or arsenic iodide. Small 
doses should be given at short intervals, with discon- 
tinuance of the medicine at the end of a week. 

Bladder, Disease of the. — Is of decided benefit 
in paralysis of the bladder ; a dose every three hours. 

Bronchitis. — Useful in small doses in chronic bron- 
chitis as a respiratory stimulant. 

Cerebral Anaemia. — Adapted to the poorly nour- 
ished, asthenic cases along with trinitrin ; a dose of 
each every two to four hours. In passive congestion, 
which I have termed symptomatic cerebral anaemia, it 
should be employed in combination with the biniodide 



172 



THE POCKET PHARMACY. 



and ipecac, for the purpose of correcting defects in 
vascular tension. 

Cholera, Asiatic. — Unfortunately in this disease, 
owing to the action of strychnine arseniate upon the 
muscular coat of the bowels, the remedy does not 
promise as much as quinine, although it might be ad- 
vantageously combined with atropine sulphate. 

Cholera Infantum. — Is given in minute dosage, 
alone or with camphor ; a pill is dissolved in four 
ounces of camphor water, and half a teaspoonful given 
every hour or two. 

Chordee. — Used occasionally in place of cannabis 
indica, to counteract the physical depression caused by 
gelsemium ; a dose every four hours. 

Chorea. — Occasionally employed, but can not be 
regarded as of much benefit unless minute doses are 
used, say one pill daily in solution taken at intervals 
of an hour. 

Climacteric Disorders. — Useful as a nervine and 
general tonic, and may be used to correct the tendency 
to constipation and pelvic congestions, together with 
salines. 

Colic, Intestinal. — Useful principally for its stimu- 
lant action, to meet the depression following an at- 
tack ; a pill every two to four hours. 

Constipation. — Is given alone or with atropine 
sulphate in the simple cases due to a want of intestinal 
secretion ; a dose three times daily. In beginning 
treatment it is advisable to have the patient take the 
medicine half an hour before breakfast, following it by 
hot water or a solution of peroxide of hydrogen. 

Debility. — In appropriate dosage, with suitable in- 
termissions, it is a superior general tonic. May be 
combined with iron arseniate, arsenic sulphide, atro- 



STRYCHNINE ARSENIATE. 



173 



pine, or cannabis indica, as the conditions demand. A 
dose is taken every four hours along with suitable 
nutrition. 

Delirium Tremens. — Is generally useful in the 
early stages to correct the condition of the stomach, 
the derangement of vaso-motor tension, and as a stimu- 
lant and tonic to the cerebro-spinal system. In com- 
bination with cannabis indica, it quickly subdues vom- 
iting and promotes sleep, although hypnotics may be 
required later. A dose should be given every hour at 
first, then at less frequent intervals, but caution must 
be exercised in elderly persons with atheromatous de- 
generation and brittle arteries. The value of strych- 
nine depends to some extent upon its power to create 
a distaste for alcohol, and the indications are therefore 
distinct. 

Diphtheria. — Used to combat the paralyses fol- 
lowing attacks ; it may also be used during the prog- 
ress of the disease to meet profound depression. 

Dysmenorrhcea. — Applicable, either alone or with 
acetanilide compound, in those cases where the men- 
strual molimen is accompanied by great prostration in 
debilitated subjects; a pill is taken every two hours 
for a day, and followed by cannabis indica. 

Dyspepsia. — Especially adapted to patients who 
are " run down " ; there is anaemia, but iron is not well 
tolerated, owing to the impoverished condition of the 
blood. It may be given alone or in combination with 
pepsin and an acid when the stomach appears to be 
most at fault ; when intestinal dyspepsia is the pre- 
dominating symptom, strychnine arseniate is given 
along with Wyeth's pancreatin, one or two grains two 
or two and a half hours after meals, the diet being 
properly regulated. 



174 



THE POCKET PHARMACY. 



Dysuria. — Is best suited to the cases in which there 
is a loss of muscular tone, and may be advantageously 
combined with atropine sulphate. 

Emphysema. — Valuable for its properties as a 
respiratory stimulant, and its influence upon the mus- 
cular fibers of the air-cells; a dose every three or four 
hours. 

Enuresis. — Especially indicated in the paralysis 
of aged persons, with or without atropine sulphate. In 
case of enlarged prostate, Saw palmetto is added to the 
treatment. 

Epilepsy. — Has been employed in idiopathic epi- 
lepsy, but there must be serious doubts as to its utility, 
because, instead of benumbing the faculty of the sen- 
sory nerves, sensation is markedly increased. 

Fever. — Is employed in adynamic conditions, and 
during the marked prostration which occurs after the 
crisis when the patient complains of great weakness. 
Pneumonia, typhoid fever, and scarlet fever are exam- 
ples of this kind. A dose should be given every three 
or four hours, but should be discontinued for a day or 
two at the end of a week, strophanthus, barium chlo- 
ride, or digitalis being substituted. 

Flatulence. — Indicated when the flatulency is 
principally confined to the colon ; a dose taken mid- 
way between meals should be followed by a draught of 
hot water. 

Flushing. — In combination with atropine sulphate, 
a dose of each three times a day, prevents flushing and 
heat, by giving a sensation of increased strength and 
endurance. 

Gastralgia. — Small doses tend to restore the nor- 
mal secretions, but sodium salicylate may be required 
to correct a rheumatic condition upon which this dis- 



STRYCHNINE ARSENIATE. 



175 



order often depends ; a dose is taken with hot water 
half an hour before meals. 

Gastritis. — May be combined with ipecac; a dose 
of each after meals and at bed-hour. 

Gout. — Useful as a stimulant to the general nerv- 
ous system ; a pill is taken three or four times a day, 
along with quinine hydrochlorate or iron arseniate as 
indicated. 

Haemorrhage, Post-partum. — A most excellent 
remedy to counteract the depression ; two pills should 
be dissolved in water and given in divided doses at in- 
tervals of five or ten minutes in the course of two or 
three hours. Oxygen inhalations produce the most 
marvelous effects in these conditions ; patients should 
be encouraged to take long inspirations and distend 
the pulmonary air-cells as thoroughly as possible. 

Haemorrhoids. — Efficient when a sluggish condi- 
tion of the bowels is associated with distention of the 
colon ; a pill is taken every morning after breakfast, 
hot water being taken half an hour before eating. 

Headache. — Useful to overcome exhaustion, and 
is best given in the form of a solution in small doses ; 
a pill is dissolved in water and taken in hourly doses 
during the day. 

Heartburn. — Should be used in solution, say two 
or three pills in half a glass of water, taken in tea- 
spoonful hourly doses. 

Heart, Fatty. — In connection with iron arseniate 
and atropine sulphate, long continued, the administra- 
tion of strychnine arseniate is curative ; a pill is taken 
every four hours. 

Heart, Valvular Disease of the. — An important 
cardiac tonic, and with proper dosage continued for a 
considerable length of time valvular disease can be 



176 



THE POCKET PHARMACY. 



decidedly improved ; a dose is taken three or four times 
a day. 

Hectic. — Assists iron arseniate and other support- 
ive treatment, and is a powerful antiperiodic. The 
best results follow the employment of small doses, say 
two or three pills daily in solution in ten equal doses. 

Hiccough. — May be tried along with antispas- 
modics, but does not appear to control the spasm. 

Hypochondriasis. — A dose is taken three times a 
day along with cannabis indica ; it may be combined 
with ox-gall, mercury biniodide, quinine, or cannabis 
indica, as seems to be required. 

Hysteria. — Must not be used when there is ex- 
alted sensibility, but may be employed to counteract 
depression along with atropine sulphate. 

Impotence. — A useful remedy alone, or in combi- 
nation with phosphoric acid and cannabis indica or 
damiana. 

Intermittent Fever. — Strychnine arseniate is a 
valuable antiperiodic, second in importance to quinine, 
and may be employed with advantage in low condi- 
tions of the system during the periods in which qui- 
nine is intermitted. 

Laryngismus Stridulus.— Adapted to the very 
nervous patients ; an adult can take a dose every two 
or three hours. 

Melancholia. — Small doses long continued have a 
very favorable action ; a dose is taken three or four 
times a day, alone or with a dose of gelsemium. With 
intestinal indigestion, ox-gall and salines should be 
added. 

Myelitis. — Must be given cautiously and only in 
the subacute and chronic stage, alone or with phos- 
phorus ; a dose three times a day. 



STRYCHNINE ARSENIATE. 177 

Nervousness. — Useful in those who are over- 
worked and underfed, to tone up the nerve supply and 
promote sleep; a dose every four hours. 

Neuralgia. — Especially indicated in visceral neu- 
ralgia, alone or with copper arsenite or cannabis in- 
dica, according to the condition of the intestinal diges- 
tion. It is also of value in those neuralgias associated 
with malarial toxaemia ; a dose every two or three 
hours. 

Nyctalopia. — May have some beneficial action 
through its influence upon the nervous system. 

Perspiration. — Useful to overcome depression and 
tone up the nervous system, but large doses have an 
unfavorable effect upon peristalsis; a dose is taken 
every four hours with food. 

Pharyngitis. — Should be combined with calcium 
sulphide; a dose of each three or four times a day. 

Phthisis. — Useful to maintain the strength, but 
should be taken in comparatively small doses; a pill 
three or four times a day. 

Pneumonia. — A very important remedy to meet 
debility incident to an attack, and especially so during 
convalescence, when it should be given in connection 
with the biniodide ; a dose every four hours along with 
appropriate nourishment. 

Prolapsus Ani.— An efficient remedy for the cor- 
rection of constipation due to a relaxed condition of 
the colon ; a dose is taken every four hours, and the 
bowels relieved by salines or by enemata. 

Prolapsus Uteri. — Useful to restore the integrity 
of the supports ; a dose is taken three or four times 
daily, in connection with the regular employment of 
the hot douche, containing a solution of the peroxide 
of hydrogen (Marchand's) or copper arsenite. 
is 



i 7 8 



THE POCKET PHARMACY. 



Ptosis. — Must be continued in small doses for some 
time ; a pill three times a day. 

Puerperal Fever. — May be required to meet the 
depression incident to the treatment of so grave a dis- 
ease, and should only be employed under the personal 
supervision of the physician or a competent nurse ; a 
dose is taken every hour or two. 

Purpura. — May be used in case there is great de- 
pression, alone or with quinine, to improve digestion 
and re-enforce the nervous system. 

Pyrosis. — Useful when a simple stomachic tonic is 
indicated ; a dose is given before and after meals. 

Scarlet Fever. — Indicated during the later stages 
and in convalescence, especially when we have to deal 
with paralysis. In case of great cardiac depression, 
strophanthus is more prompt. 

Sciatica. — As this disease is often associated with 
some cardiac difficulty, it is advisable to make strych- 
nine arseniate a portion of the after-treatment. 

Seasickness. — Will be useful when there is much 
prostration, with more or less constipation. 

Sleeplessness. — Adapted to those cases which are 
due to physical exhaustion ; a single dose taken in 
solution a short time before retiring will not infre- 
quently afford a comfortable night's rest. 

Spermatorrhoea. — Useful for its tonic stimulant 
properties, but phosphorus may often be added to the 
treatment with benefit. 

Sunstroke. — Adapted to heat-exhaustion, to im- 
prove the condition of the nervous system, and in the 
after-treatment of thermic fever, alone or in combina- 
nation with quinine. 

Syncope. — Should be given as a prophylactic ; it 
is especially indicated in fatty degeneration, dilata- 



STRYCHNINE ARSENIATE. 



179 



tion, and arhythmia. A dose is taken every three or 
four hours. 

Tetanus. — While relieving the symptoms mani- 
fested in the form of tonic muscular contractions, it 
exerts no special influence upon the liver, the organ 
upon which the poison is ultimately precipitated. 

Typhoid Fever. — In debilitated subjects with 
weak hearts, and in prolonged illness from this disease, 
strychnine arseniate is invaluable. It is also indicated 
in connection with the continued use of acetanilide 
compound, aconite, and gelsemium, and in threatened 
collapse, and should never be omitted during conva- 
lescence. 

Typhus Fever. — In moderately severe, and cer- 
tainly in all the bad cases, it should be employed as 
soon as the condition of the temperature warrants. 
Being a typical adynamic disease, it behooves the phy- 
sician to look well after the nutrition of the cardiac 
muscle. 

Vomiting. — Given in solution in small doses at 
short intervals, and combining with this medication 
the use of ipecac in the form of powder, a dose after 
each meal, very few cases of vomiting of pregnancy will 
fail to respond favorably. By substituting for the ar- 
seniate the nitrate, the treatment outlined is of service 
in chronic alcoholism, but the remedy must be pushed, 
and no alcoholic liquids permitted. 

Yellow Fever. — Would be strongly indicated in 
connection with other appropriate treatment for the 
purpose of sustaining the vital powers. 



l8o THE POCKET PHARMACY. 



TRINITRIN. 

Each tablet, pill, or granule contains one two-hun- 
dred-and-fiftieth grain of the drug (Nitroglycerin). 

Albuminuria. — In both acute and chronic albu- 
minuria, trinitrin is given with great benefit. Small 
doses ( x / 250 grain) should be given at intervals of two 
hours and long continued, the patient being instructed 
to maintain the recumbent posture as much as possible. 

Amaurosis and Amblyopia. — Small doses are 
useful when the optic nerve is affected. Pilocarpine 
hydrochlorate and strychnine arseniate are indicated 
when the trouble is due to excessive use of tobacco or 
alcohol. 

Angina Pectoris. — Trinitrin was first advocated 
for the relief of angina pectoris by Ringer and Murrell, 
and has proved a useful addition to therapeutics. 
Where atheromatous degeneration has taken place, or 
is suspected, great caution is required. During the 
emergency the patient should maintain the recumbent 
posture, and alarming symptoms due to pain are to be 
met by the hypodermatic use of morphine and atro- 
pine. A tablet of trinitrin can be dissolved in the 
mouth at intervals of five or ten minutes, and this 
should be followed by the administration of iron 
arseniate or arsenic sulphide, according to indications, 
with a view to correct the derangement of vascular 
tension upon which the disorder depends. 

Asthma. — This remedy is highly prized by many 
practitioners as an abortifacient in spasmodic asthma, 
although it is difficult to outline distinctly the class of 
cases in which it can be exhibited with uniform success. 
The author is of the opinion that trinitrin succeeds 



TRIXITRIN. !8i 

best in those cases marked by greatly increased arte- 
rial tension, but more especially the tension of the 
arterioles, in which we may assume that the movement 
of the blood in the pulmonary capillaries is intermit- 
tent. While neither hepatic nor renal cirrhosis are 
concomitants of this condition, we find indications of 
failure in both organs, and as adjuvants to the treat- 
ment, therefore, we should select the biniodide ; 
arsenic and strychnine arseniate will be included in 
the symptomatic treatment, but the value of ipecac 
must not be overlooked. The latter in combination 
with strychnine arseniate and trinitrin, a dose of each 
every three hours, will often prove curative. 

Having a correct conception of the pathological 
conditions present in asthma, we are in a position to 
understand the effects produced by trinitrin. The 
action of the drug is almost instantaneous, but it is 
transient, or evanescent, and the dose must be repeated. 
It has the effect of favoring the movement of blood in 
the capillaries, although this is rather the indirect than 
the direct action. The intermittent or stagnant blood- 
current in already distended capillaries is forced on- 
ward by the increased tension produced in the systemic 
circulation by the exhibition of trinitrin, and thus 
tissue-change is favored. 

Cerebral Anaemia. — Is useful in this condition to 
overcome arterial tension, indicated by a band-like 
feeling around the head and blanched face ; a dose is 
taken every hour or two together with gelsemium or 
strychnine arseniate, according to the indications pres- 
ent. When the pulse is rapid, gelsemium should be 
exhibited ; on the contrary, when it is slow, the strych- 
nine preparation is indicated. An occasional saline is 
also of much benefit. 



X 82 THE POCKET PHARMACY. 

Cerebral Congestion. — May be given cautiously 
to drunkards suffering from congestion, along with 
aconite or gelsemium in the active variety. In the 
passive form dependence must be placed upon purga- 
tives and local blood-letting. 

Climacteric Disorders. — Is of temporary value 
in emergencies, to overcome cerebral anaemia ; a dose 
is taken every two hours for several days. 

Coma. — Is adapted to that following acute alco- 
holism, or from narcotic poisons and asphyxiation from 
coal gas. A pill is dissolved in a few drops of water 
and introduced cautiously inside the lips, and repeated 
at short intervals as required. 

Cough. — Indicated in the class of cases having an 
asthmatic or suffocative character. May be used in 
connection with strychnine arseniate for the tonic 
effect, of the latter ; a dose every hour or two. 

Epilepsy. — When sufficient time intervenes be- 
tween the aura and seizure, trinitrin may avert it, but 
this seldom occurs. It may, however, be used to cut 
short an attack ; five or ten tablets may be dissolved 
in as many minims of water, and a drop placed inside 
the lips every minute until relief is afforded. 

Gastralgia. — Trinitrin has some reputation for 
easing the pain of this disorder ; a dose is given every 
ten minutes for an hour for the emergency, but other 
treatment should follow. 

Headache. — Is used in the class of cases present- 
ing symptoms just the opposite of those where aconite 
is indicated. The face is blanched and the patient ex- 
periences a feeling of constriction about the head ; a 
pill should be dissolved in the mouth every ten minutes 
for an hour. 

Heart, Dilated.— Adapted to the class of cases in 



TRINITKIN. 



183 



which there is contraction of the arterioles ; a dose is 
taken every two or three hours, and the patient ad- 
vised to remain in the recumbent posture as much as 
possible. 

Heart, Hypertrophied. — May be alternated with 
gelsemium, and is especially indicated in small doses 
to meet increased arterial tension affecting the arteri- 
oles ; a dose is taken three or four times a day. 

Hiccough. — Has been advocated for the relief of 
this affection, but seems to have little or no influence 
over the spasm. 

Nephritis, Acute. — Adapted to the cases with 
high arterial tension ; a dose is taken every hour, the 
patient to retain the recumbent posture. 

Neuralgia. — Useful in the cases in which neuralgia 
is associated with derangement of the circulation, slow 
pulse, blanched face, and high arterial tension; a dose 
is taken every five or ten minutes for an hour. 

Phthisis. — Sometimes very serviceable in over- 
coming dyspnoea and "sinking spells." A dose is 
given every few minutes dissolved in the mouth, and 
followed by strychnine arseniate. 

Sunstroke. — Of value in collapse occurring from 
heat-exhaustion. In addition, a hot bath is recom- 
mended and the administration of atropine sulphate or 
caffeine, for their influence upon the circulation and 
cerebral centers respectively. 

Syncope. — Is often a valuable remedy when the 
condition of the heart warrants, and we have indica- 
tions of contraction of the arterioles. It should be 
used cautiously with fatty degeneration, but will often 
save life when syncope occurs in connection with anaes- 
thesia and that occurring from the abuse of narcotics. 



1 84 THE POCKET PHARMACY. 



ZINC SULPHO-CARBOLATE. 

Each tablet, pill, or granule contains one -half grain 
of the drug. 

Cancer. — The antiseptic properties of this remedy 
commend it for the treatment of cancer of the stomach ; 
a dose every two or three hours. 

Cholera, Asiatic. — While occupying a place sec- 
ond to copper arsenite, there may be cases in which 
the zinc salt would prove more useful, administered 
internally and used in the form of enema. 

Cholera Infantum. — A dose may be given to in- 
fants every hour or two internally, and a solution em- 
ployed by enema twice a day. Diet and hygiene are 
of paramount importance. 

Diarrhoea. — A very efficient remedy in all cases 
where the stools are offensive and frequent ; a dose is 
given every hour or two to a child five years of age. 

Flatulence. — The antiseptic properties of the zinc 
preparation should make it a useful remedy in the 
treatment of flatulence ; adults should take two or three 
pills before meals and at bed-hour. 

Gastric Ulcer. — Is valuable for its antiseptic prop- 
erties like the biniodide, but is in no sense a hepatic 
stimulant like the latter drug; one or two pills should 
be taken at intervals of two hours. 

Gleet. — A solution in water was originally em- 
ployed for the relief of urethral affections in this city 
as early as 1867. Probably its microbicidal properties 
would make it a valuable remedy for the relief of this 
disorder, as it can be used in the form of a solution. 

Gonorrhoea. — The same advice is appropriate here 
as given under the head of gleet. When employed, it 



NUCLEIN SOLUTION. 1 85 

should be used in weak solution and at frequent in- 
tervals. 

Typhoid Fever. — Is a valuable and promptly act- 
ing antiseptic in this disease ; a dose — one or two pills 
for adults — is given every hour while the patient is 
awake, although in severe cases, with offensive stools, 
as much as two grains may be given every two hours. 
It is also employed in these cases in the form of ene- 
mata, the colon being flushed with a weak solution 
night and morning. 

Yellow Fever. — Possibly this remedy, used in the 
manner recommended for the exhibition of copper ar- 
senite, would prove useful in the treatment of yellow 
fever. 



NUCLEIN SOLUTION. 

Each tablet, pill, or granule contains 48 / I50 minim, 
approximately, one-third of a minim of the standard 
solution. For hypodermic use, and in special instances 
as advocated in the following notes, the solution only 
should be employed ; dose, five to ten to twenty min- 
ims, diluted with boiled or sterilized water.* The ordi- 
nary hypodermic syringe is employed under antiseptic 
precautions, the injections being made at some indif- 
ferent point. 

* The standard nuclein solution from animal sources is the origi- 
nal form in which this product was first brought to the attention of 
the medical profession (American Therapist, February, 1894), and 
during the interval which has since elapsed I have discovered no 
cause to warrant or require any modification of my earlier teachings, 
except to indorse the form of a dilution to one-fourth strength (me- 
dicinal solution) for hypodermic administration. 



!86 THE POCKET PHARMACY. 

Anaemia. — Nuclein should be given, ten to thirty 
minims of the medicinal solution daily in divided doses, 
using sherry wine or cordial as a vehicle. Moderate 
exercise in the open air is recommended, together with 
hot baths and massage when deemed necessary. The 
importance of nutritious, easily digested food, taken at 
regular hours, can not be over-estimated. 

In anaemia there is usually a sluggish condition of 
the hepatic function, and frequently marked constipa- 
tion with a relaxed condition of the tissues, a morbid 
complexus over which this remedy exercises no direct 
control. When a mild saline, taken one hour before 
breakfast, fails to correct the derangement, recourse 
should be had to ox-gall combined with strychnine 
arsenite, and some form of mercurial in small doses, 
either calomel or the biniodide. When the left side of 
the liver is at fault, prompt relief is afforded by exhib- 
iting the biniodide, while for the right side better results 
are secured from calomel in small doses, together with 
small doses of podophyllin resin, say about one-twen- 
tieth grain. 

The anaemia dependent upon influenzal debility is 
especially amenable to nuclein medication, in which 
case strychnine arsenite should be used as an adjuvant, 
one-thirty-second of a grain to be given every two 
hours until four o'clock in the afternoon. Substan- 
tially the same line of treatment should be followed 
in the case of anaemia incident to long-continued ill- 
ness, care being observed as to the effect of the strych- 
nine salt upon the heart* 

Pernicious anaemia is a malady in which the thera- 
peutic virtues are indicated from a strictly physiological 
standpoint ; hence nuclein must prove an important 
factor in counteracting the tendency of this malady. 



NUCLEIN SOLUTION. 



18/ 



It is strongly recommended in conjunction with the 
strychnine arsenite. In this class of cases treatment 
should begin with hypodermic administration, twenty 
to thirty minims of the medicinal solution being inject- 
ed daily. 

Arthritis, Rheumatoid. — The daily administra- 
tion of nuclein, ten to twenty minims, as recommended 
in anaemia, creates a sense of well-being, probably by 
stimulating leucocytosis and increasing oxidation ; 
there is general improvement of the digestive capaci- 
ty with a lessened tendency to insomnia. Locally it 
will prove effective to have salicylic-acid paste — two 
drams to the ounce of lanolin — applied to the painful 
joints two or three nights in succession, giving at the 
same time small doses of hyoscyamine, one one-hun- 
dred-and-twenty-fifth grain every two hours, together 
with medicinal doses of calomel at short intervals for 
a day at a time. 

In arthritis (chronic), nuclein medication is fre- 
quently most effective; especially is this the case when 
the disease has resisted the usual routine treatment 
and anaemia is a marked feature. 

Asthma, Humid. — This malady is quickly relieved 
by nuclein. The patient takes ten to thirty minims of 
the medicinal solution daily in divided doses, with 
sherry as a vehicle. In case there is well-marked mus- 
cular relaxation, so common in such cases, the patient 
should have strychnine arsenite, one-sixteenth grain, 
every two hours for several days. 

Humid asthma in autumn is not infrequently a con- 
comitant of indigestion and so-called "biliousness," 
when it is necessary to instruct the patient as to diet, 
with or without the saline, as recommended under the 
head of anaemia. Comparatively few practitioners 



!88 THE POCKET PHARMACY. 

recognize the importance of the latter suggestion; 
hence sufferers from this ailment, when medical treat- 
ment fails, resort to purgatives, at best a questionable 
procedure. Here purgatives are absolutely contra- 
indicated, because the principal difficulty is gen- 
erally in the stomach, the result of auto- or self- 
infection. 

Boils. — In addition to the internal administration 
of calcium sulphide and salines, nuclein should be used 
hypodermically, and, where practicable, just outside of 
the margin of the inflamed area, for the double pur- 
pose of arresting the entrance of micro-organisms by 
reinforcing the normal inflammatory leucocytosis, and 
by promoting tissue change and the elimination of 
waste products through the proper channels rather than 
through the diseased tissues. Ten to twenty minims 
of the medicinal solution should be introduced, as di- 
rected, twice daily, and the entire area encircled as 
rapidly as possible. Twelve years ago, when I first 
condemned the use of poultices in the treatment of 
boils, carbuncles, and abscesses, my advice was laughed 
to scorn, but all successful surgeons now realize its 
practical bearing, and physicians generally have come 
to regard the poultice with disfavor. By following the 
plan here advised, distinct gain in the condition of the 
patient may be noted from day to day, prompt recov- 
ery being the rule. 

Bright'S Disease. — That nuclein will arrest the 
progressive renal degeneration characteristic of Bright's 
disease is quite incredible, yet I have witnessed in sev- 
eral well-marked cases the rapid disappearance of al- 
bumin, together with decided improvement in the 
general condition. Of course, I did not depend upon 
nuclein alone, but introduced the treatment during a 



NUCLEIN SOLUTION. 



189 



period when there could be no question as to the evi- 
dences in its favor. As the condition of the tissues in 
this disease contraindicate the hypodermic method, the 
remedy should be given in the usual manner, with wa- 
ter or a light wine as a vehicle, ten to twenty minims 
of the medicinal solution three times a day. 

Bronchitis, Subacute and Chronic. — The marked 
therapeutic effects of nuclein are well illustrated in the 
treatment of subacute and chronic bronchitis. From 
one to three injections of twenty minims of the medici- 
nal solution in as many days, with strychnine arsenite 
during the same period, will almost certainly correct 
the disorder. When the patient rebels against the 
hypodermic method, two tablets should be given every 
two hours, the strychnine salt being administered at 
the same time. Should there be a cause, or conditions 
predisposing to the malady remaining, other treatment 
may be required. Should there be present a throat 
complication, or naso-pharyngeal catarrh, potassium 
bichromate is to be substituted for the strychnine salt, 
one-twenty-fifth grain every two hours. 

Broncho-pneumonia. — Since the advent of influ- 
enza in 1889 this disorder is usually characterized by 
profound depression of the vital powers, so that, in 
addition to the reinforcement of the tissues and body 
fluids by an artificial supply of nuclein, a cerebro- 
spinal stimulant is demanded ; hence, while adminis- 
tering nuclein hypodermically, ten to thirty minims at 
intervals of six hours, strychnine arsenite should be 
given in full doses, one-sixteenth grain every two 
hours. With continued high temperature, of course, 
these directions will have to be modified. A tempo- 
rary expedient to reduce rapid pulse-rate will be found 
in gelsemium, but this should be continued only for the 



190 



THE POCKET PHARMACY. 



first or second day of the treatment, owing to the 
depressing effect upon the cardiac apparatus. 

Cancer. — The microbic origin of cancer still being 
sub judice, we are necessarily compelled to regard it as 
arising from occult pathological changes in the cells 
of the organ or structure affected. Hence, the func- 
tion of nuclein being to restore and maintain normal 
metabolism, we should conclude a priori that the rem- 
edy would prove effective in arresting the abnormal 
cell-growth. Although comparatively few reports have 
appeared in current literature showing the favorable 
action of the remedy, personal observation in a lim- 
ited number of well-marked cases warrant me in advis- 
ing its hypodermic employment whenever the growth 
can be completely encircled by the injections. The 
solution should be brought into contact with the nor- 
mal tissues threatened by the extension of the disease ; 
thus, a healthy zone can be formed beyond which the 
infection does not penetrate. Ten to twenty minims 
of the medicinal solution should be injected twice 
daily until this object is attained. Cancer of the 
breast appears to be a promising field for this method 
of treatment, provided it is begun early, and before 
surgical operations have produced the actively malig- 
nant tendency. 

Catarrh, Nasopharyngeal.— Owing to the vas- 
cularity of the tissues of the naso-pharyngeal space 
and constant activity of the cells in eliminating w T aste 
products, overwork is followed by arrest or suspension 
of function, and subsequently degenerative changes 
take place, thus making naso-pharyngeal catarrh a 
self-perpetuating disease. Increased secretion, instead 
of being regarded as an aggravation of the disease, 
must, in the light of modern physiological revelations, 



NUCLEIN SOLUTION. 



I 9 I 



be taken as Nature's curative process, by which an 
increased supply of the so-called "defensive proteids" 
are sent to restore the breach. Hence, the value of 
nuclein as a physiological reconstructive, to restore 
the secretions to a condition approaching the normal, 
to reinforce leucocytosis, to promote oxidation in the 
organism and favor the elimination of waste products. 
Nuclein should be given hypodermically in full doses 
daily, together with potassium bichromate and strych- 
nine arsenite as adjuvants. Proper attention should 
be given to dietetic and hygienic requirements. 

Chlorosis. — Substantially the same directions are 
to be followed as in the case of anaemia, except that 
the ox-gall combination should be alternated with 
some readily soluble iron preparation ; the arseni- 
ate in the form of a tablet will often be found suf- 
ficient. 

Cholera Infantum. — A number of ideal remedies 
have been recommended in this disease, but all with a 
view to correct the disorder through chemical activi- 
ties. The demand for a restoration of the normal 
physiological metamorphosis has been overlooked and 
Nature's efforts to that end misinterpreted. Since the 
abnormally increased intestinal secretions show an at- 
tempt to augment the nuclein supply, we may arrest 
the disease and cause the symptoms to subside by the 
liberal use of an artificially prepared nuclein. A few 
doses only are required to create a favorable change, 
and, as a professional friend says, " when the patient 
recovers from the acute manifestations of the disease, 
he is well," there being no lingering period of conva- 
lescence. A child five years of age or under should 
have twenty minims of the medicinal solution in di- 
vided doses daily. Intestinal antiseptics are not con- 



IQ2 



THE POCKET PHARMACY. 



traindicated, but we must not overlook hepatic stimu- 
lants. 

Debility. — This is rather a vague term, but is 
expressive of a condition frequently met with by the 
physician under various and singular circumstances. 
Thus, during convalescence from different ailments 
the progress toward recovery is arrested without 
apparent cause ; the digestive apparatus appears to 
be incapacitated and the mental powers flag, all 
symptoms pointing to dementia or general paresis. 
Digestants fail, diffusible stimulants fail, and cardiac 
stimulants must be abandoned because of the in- 
somnia induced. It is here that nuclein steps in and 
turns defeat into victory. The patient should have 
full doses at short intervals, all other medicaments, 
except cerebro-spinal stimulants, to be discontinued. 

Diabetes Mellitus. — A patient now living and in 
good health at the age of sixty-five, who in 1894 was 
passing over a gallon of urine daily containing twenty- 
four grains of sugar to the ounce, is reasonably con- 
clusive evidence in favor of nuclein medication in this 
disease. A selected dietary was insisted upon, sugar 
discarded and saccharin substituted, alcoholics dis- 
couraged, and moderate exercise recommended. Since 
patients of this class are long under treatment, inter- 
nal administration must be employed a great portion 
of the time, but full doses should be given. A good 
lithia water, freely used, is an important auxiliary. 
Dioscorea is a useful adjuvant, with an occasional 
mercurial to stimulate the hepatic function. 

Diarrhoea. — In addition to the careful restriction 
of the diet and the avoidance of exercise, but little is 
required beyond a few doses of copper arsenite or 
mercury biniodide — according to the conditions pres- 



NUCLEIN SOLUTION. 



193 



ent — with plenty of hot water and nuclein to over- 
come the later prostration. Personal observation 
warrants the claim that patients thus treated are well 
under way toward recovery before the disease is ordi- 
narily established under routine methods. For a child 
five years of age, or less, fifteen minims of the medici- 
nal solution should be administered daily in some 
palatable vehicle. With paroxysmal attacks of pain 
in the small intestine give small doses of copper 
arsenite. When pain is conspicuous as a factor, with 
free, watery stools, indications point to the liver as 
the offending organ, in which case small doses of the 
mercury biniodide should be employed. 

Diphtheria. — In this disease a microscopic exami- 
nation of the blood will generally show a greater or 
less leucocytosis, a symptom which I can not regard 
otherwise than as an effort of Nature to increase cell 
resistance — that is, to promote oxidation and favor 
elimination — thus measurably restoring the tissues and 
body fluids to the normal. The introduction of an 
artificially prepared nuclein in this disease is calculated 
to augment the physiological functions, since it favors 
cell activity, and, besides, renders the physical char- 
acter of the fluids inimical to the welfare of bacteria 
and their products. Being absolutely non-toxic, it can 
be given freely without danger, internally or hypoder- 
mically, under the usual antiseptic precautions. 

In ordinary cases twenty minims of the medicinal 
solution should be injected at some indifferent point 
every four hours during the first two days. Locally, 
a recently prepared peroxide of hydrogen is employed 
at short intervals. 

When nuclein medication is instituted early in the 
disease the duration of an attack is materially short- 
13 



!Q4 THE PCCKET PHARMACY. 

ened, convalescence being recognized by subsidence of 
the temperature. Serious cases are favorably modified, 
and generally under this treatment make an uneventful 
recovery ; all of which is confirmed by clinical reports 
in current medical literature of the past seven years. 

In the so-called " diphtheritic sore throat," occur- 
ring in adults and children, a non-contagious malady 
in the early stage, nuclein is a specific. From five to 
ten drops of the medicinal solution should be taken 
every hour or two until relieved ; or two tablets may 
be taken at the same intervals. 

Dysmenorrhea. — Occurring as a result of sub- 
oxidation in anaemia, chlorosis, and tubercular infec- 
tion, nuclein affords relief ; but measures should be 
taken with a view to remove the cause. As a tempo- 
rary measure strychnine arsenite should be given in 
full doses, to be followed by hematinics and hepatic 
stimulants as adjuvants to nuclein medication. 

Eczema. — The subacute and chronic variety is dis- 
tinctly improved by nuclein, in doses of ten drops of 
the medicinal solution three times a day, together with 
salines and a restricted diet. Special attention should 
be given to the intestinal digestion, to the end that 
excessive acidity may be corrected. 

Exophthalmus. — With nuclein hypodermically to 
restore a normal metabolism, gelsemium to allay cere- 
brospinal irritation, together with rest and forced feed- 
ing, comparatively few cases in the early stage fail to 
respond favorably to treatment. Ergotin and strych- 
nine arsenite should be alternated with the above at 
intervals of a week, and care must be exercised to 
maintain a healthy condition of the alimentary canal, 
much benefit being derived from flaxseed tea and mu- 
cilaginous drinks. 



NUCLEIN SOLUTION. 



195 



Fever. — Nuclein is always indicated in the case of 
fever, because of the defective metabolism incident 
thereto, but difficulty arises owing to the rapid pulse- 
rate and high temperature. Compulsory reduction of 
fever is secured by the employment of one of the many 
coal-tar derivatives ; but these products interfere with 
elimination and create profound depression of the 
nervous mechanism, and their popularity is on the 
wane. They are specially objectionable because they 
lessen the oxygen-carrying capacity of the blood. 
With arterial sedatives, gelsemium, aconite, and vera- 
trum, to be determined by the conditions present, nu- 
clein possesses every requisite of an efficient febrifuge 
in the absence of serious organic complications. It 
should be given in moderate dosage at short inter- 
vals. 

Gonorrhoea. — A weak solution, ten per cent of the 
medicinal product, is effective in gonorrhoea. Hydro- 
gen dioxide is first employed to cleanse the urethra, 
then nuclein used, care being taken to distend the 
urethral mucous membrane. Copper arsenite solution 
should be alternated with the nuclein. 

Influenza. — With the morbid complexus charac- 
teristic of influenza as it now appears, no single rem- 
edy, considered from a physiological standpoint, is so 
fully qualified to meet the demands upon the system, 
and clinical experience confirms the physiological de- 
ductions whatever type of the disease presents. High 
temperature here, as in most pathological conditions, 
is solely a product of defective cell metabolism, with 
faulty elimination of waste products ; hence the impor- 
tance of securing at the earliest possible moment a 
restoration of the cell function. In young persons arte- 
rial sedatives should be employed in the early stage, 



196 



THE POCKET PHARMACY. 



with or without calcium sulphide or potassium bichro- 
mate, nuclein being administered continuously for its 
influence upon tissue change and upon oxidation. The 
efficiency of nuclein as an immunizing agent in other 
infectious diseases should commend it for this purpose 
in influenza, and its value in this direction has been 
frequently noted. Ordinarily the dose in this disease 
is two tablets every two hours ; when given hypoder- 
mically, the dose should be ten to thirty minims once 
or twice daily. 

Insomnia. — Nuclein is especially indicated when 
the insomnia appears as the result of suboxidation 
with defective elimination. In this connection the 
writer desires to emphasize the necessity of looking 
well to the natural emunctories, and particularly to 
the condition of the hepatic function. Generally two 
tablets every two hours will prove sufficient, but in 
those instances where the physical condition is much 
reduced hypodermic medication is superior, being more 
prompt in its action and more efficient as a tonic stim- 
ulant. 

Malaria. — So many favorable reports have reached 
me commending nuclein medication for malaria that it 
will be sufficient here to give brief directions for its 
employment. In the early stage of an attack a full 
dose, thirty minims of the medicinal solution, should 
be administered daily for several days, after which the 
same amount can be taken daily by the mouth until all 
symptoms have subsided. In chronic cases and recur- 
rent malaria, unless the patient is greatly reduced in 
strength, the tablets may be given, two every two hours 
for a week. To physicians who have the facilities, the 
daily examination of the blood while the patient is 
taking nuclein will prove most interesting. 



NUCLEIN SOLUTION. 



I 9 7 



Measles. — Ordinarily a benign affection, there are 
times when cell function appears to be held in abey- 
ance, as when the eruption fails to develop, or there is 
failure in elimination, when the restorative power of 
nuclein is well illustrated. A child five years of age 
or under takes a tablet every two hours. 

Melanosis. — The medicinal action of nuclein upon 
cell function is well marked in the case of melanosis, 
perfect recovery taking place in a short time. The 
dose is two tablets every two to four hours. 

Neurasthenia. — The judicious employment of 
this remedy in conjunction with hepatic stimulants, as 
outlined under the head of anaemia in this section, will 
prove a revelation to many physicians who have here- 
tofore relied upon the mechanico-physiological stimu- 
lants to combat nervous prostration. Improvement is 
apparent within twenty-four hours, but patients must 
be kept under observation for some time, until the 
various functions have been restored to a condition 
approaching the normal. Diet and hygiene require 
attention, and in numerous instances a temporary 
change of climate is attended with happy results. 
The patient should have two tablets before each 
meal, two between meals, and at night on retiring. 

Night Sweats. — Nuclein is of value in cases 
where defective metabolism is a factor, whether aris- 
ing from debility or from continued employment of 
anodynes or narcotics. Sometimes nuclein alone is 
sufficient, but usually it is necessary to employ ad- 
juvants. 

Pharyngitis, Follicular. — Prompt benefit attends 
the use of nuclein in this disorder, but curative effects 
must be secured through the conjoint employment of 
calcium sulphide at first, with potassium bichromate 



ig8 THE POCKET PHARMACY. 

later, for their local action upon the diseased follicles. 
Dose, two tablets every three hours. 

Rheumatism. — Inflammatory and muscular rheu- 
matism in the subacute stage are benefited by nuclein 
treatment through the action of the remedy upon oxi- 
dation and elimination of waste products. Its employ- 
ment will prove most helpful, and the greater the de- 
bility the more marked will be the effects, as contrasted 
with the usual modes of treatment. Twenty to thirty 
minims of the medicinal solution should be adminis- 
tered daily. 

Scarlet Fever. — To secure immunity against the 
disease, a child five years of age should have ten drops 
of the medicinal solution every two hours for the first 
day after exposure, then at intervals of four hours for 
at least a week. However, treatment of the disease 
by nuclein is about as simple as immunization, patients 
being convalescent at the end of a week. Throat 
symptoms quickly subside, vomiting ceases, while the 
eruption appears and begins to fade so rapidly that 
the medical attendant can scarcely believe he has to 
deal with a malady hitherto regarded with such dread. 
A child five years of age should have two tablets every 
two hours, or its equivalent in the form of the solution, 
for the first three days, after which the intervals may 
be lengthened. Complications are so rare that treat- 
ment need not be considered. 

Sciatica. — Useful when patient is much debili- 
tated, and should be used with rhus as an adjuvant. 
Two tablets every two hours. 

Tonsillitis. — Had nuclein medication been origi- 
nally limited to the treatment of tonsillitis, or quinsy, 
the marvellous effects of the remedy in this affection 
alone are sufficient to bring it to the favorable atten- 



NUCLEIN SOLUTION. 



I 99 



tion of medical men throughout the entire world. It 
is practically a specific. Amelioration of all the symp- 
toms follows the administration of the first dose, and, 
as a rule, recovery is well under way at the end of the 
first twenty-four hours. It may be given in tablet 
form or solution. Dose for an adult, two tablets every 
two hours. 

Tuberculosis. — The treatment of this disease by 
the usual medicinal substances has shown in recent 
years how imperfect has been our conception of the 
malady. Fortunately, the discovery of tuberculin as a 
test for its presence has thrown a strong side light 
upon the morbid condition, and there is a promise to 
future generations of comparative freedom from its 
dangers, provided that reasonable precautions are 
taken to avoid exposure. In this connection I shall 
not attempt to discuss whether tuberculosis is itself a 
primary infection, or a resultant arising from morbid 
conditions in which the bacillus represents a cycle of 
bacterial life. However, I shall insist upon the im- 
portance of avoiding the exposure, now recognized 
through our knowledge of the pathological indications 
of susceptibility to tubercular invasion. 

Diet and hygiene undoubtedly stand first in esti- 
mating our ability to arrest or control the disease in 
each individual case, and closely linked with this is the 
question of assimilation, primary and secondary, cli- 
matic conditions being of secondary importance. In 
tuberculosis there is a more or less constant nervous 
element to contend with, owing to the faulty elimina- 
tion of waste products incident to irregular oxidation. 
Hence the apparent need for anodynes and soporifics ; 
but at the end of a day or a week the morbid condi- 
tions remain unchanged. The recuperative powers 



200 THE POCKET PHARMACY. 

derive no apparent benefit from this treatment, because 
it fails to augment the assimilative capacity. Diges- 
tive leucocytosis is absent because the sensory nerve 
supply of the digestive apparatus is obtunded, while 
the diminished oxygen-carrying capacity of the red 
blood-cells, together with faulty primary assimilation, 
reduces to a minimum the capacity of the secondary 
assimilation. And the insidious progress of tubercular 
invasion is such that no inflammatory leucocytosis 
occurs. From whatever view-point we study the dis- 
ease there is one factor that dominates all others, 
namely, defective leucocytosis ; and here lies the touch- 
stone, the secret of the successful treatment of this 
malady in its early stages. 

A normal condition of the leucocytic function can 
be established and maintained in the human system by 
the introduction of artificially prepared nuclein as a 
substitute for the more or less constant product of the 
polynuclear white blood-corpuscles. Thus we secure 
the aid of a powerful yet non-toxic antiseptic, a stimu- 
lant to the oxidation processes, and incidentally a nerve 
sedative; and it is not improbable that this substance 
is also a factor in maintaining the integrity of the red 
blood-cells. 

The conditions here outlined conform with the 
most recent physiological investigations, and clinical 
observation confirms in detail all the claims advanced, 
numerous contributions to medical literature in recent 
years being in evidence. Personally I am convinced 
that nuclein medication as the basis will result in more 
recoveries, more patients improved, and a larger num- 
ber made comfortable than from any mode of treat- 
ment heretofore advocated. 

Administration of the remedy will be determined 



NUCLEIN SOLUTION. 201 

to some extent by the tissues involved, by the age and 
physical condition of the patient, and due considera- 
tion must be given to the character (type) and stage 
of the disease. The best results follow the hypoder- 
mic employment of nuclein in tubercular infection, 
twenty to thirty minims of the medicinal solution being 
injected daily for a week. At the expiration of this 
period nuclein should be used on alternate days with 
the copper arsenite solution (see page 81). In case 
the patient rebels, the same amount daily can be given 
by the mouth, and, in the absence of solution, two 
tablets can be given every two hours, beginning 
early in the morning and continuing until late in the 
evening. 

Typhoid Fever. — Substantially the remarks made 
with reference to leucocytosis in tuberculosis apply as 
well to the physiological conditions in typhoid fever, 
as, under ordinary circumstances, there is no leucocy- 
tosis. By creating an artificial leucocytosis through 
the administration of nuclein from animal sources the 
character of the disease is modified, so that the tem- 
perature chart, when fever continues, shows a record 
precisely the same as simple continued fever, and the 
blood test does not give the Widal reaction. Gener- 
ally the disorder subsides within a few days after treat- 
ment is begun, whether early or late in the disease, 
and the subjective sensations of the patient are almost 
immediately improved. The reports of Dr. Thomas 
W. Jackson, acting assistant surgeon, U. S. A., cover- 
ing cases seen in the Government Hospital (Camp 
Poland) at Knoxville, Tenn. (1898) (New York Medi- 
cal Journal, February 11, 1899), show in the most con- 
vincing manner the advantages of nuclein medication 
in typhoid fever. 



202 THE POCKET PHARMACY. 

The medicinal solution should be employed in pref- 
erence to tablets, the dose being ten to twenty minims 
(not drops) every three hours, beginning at six in the 
morning and continuing until nine at night. With 
each dose of nuclein the patient takes a tablet of 
copper arsenite containing one one-hundredth of a 
grain. 



THERAPEUTIC INDEX. 



Abscess : 

Calcium sulphide, 58. 
Acidity of the Stomach : 

Ipecac, 106. 

Mercury biniodide, 121. 
Acne : 

Arsenic sulphide, 36. 

Calcium sulphide, 58. 
Addison's Disease : 

Iron arseniate, no. 
After-pains : 

Bryonia, 52. 

Camphor, 71. 

Copper arsenite, 82. 

Gelsemium, 98. 

Morphine hydrochlorate, 137. 

Quinine hydrochlorate, 146. 
Albuminuria : 

Arsenic sulphide, 36. 

Atropine sulphate, 40. 

Iron arseniate, III. 

Nuclein, 188. 

Strophanthus, 167. 

Trinitrin, 180. 
Alcoholism : • 

Acetanilide compound, 17. 

Copper arsenite, 82. 

Quinine hydrochlorate, 147. 

Strychnine arseniate, 169. 
Alopecia Areata : 

Arsenic sulphide, 36. 



Amaurosis and Amblyopia : 

Strophanthus, 167. 

Strychnine arseniate, 169. 

Trinitrin, 180. 
Amenorrhcea : 

Aconite, 24. 

Calcium sulphide, 58. 

Iron arseniate, in. 
Amygdalitis, see Tonsillitis. 
Anaemia : 

Arsenic sulphide, 36. 

Copper arsenite, 82. 

Ipecac, 107. 

Iron arseniate, in. 

Mercury biniodide, 121. 

Nuclein, 186. 

Quinine hydrochlorate, 147. 

Strychnine arseniate, 170. 
Aneurism : 

Aconite, 24. 
Angina Pectoris : 

Acetanilide compound, 17. 

Aconite, 25. 

Arsenic sulphide, 36. 

Quinine hydrochlorate, 147. 

Strychnine arseniate, 170. 

Trinitrin, 180. 
Aphonia : 

Aconite, 25. 

Atropine sulphate, 40. 

Bryonia, 52. 



204 



THERAPEUTIC INDEX. 



Aphthae : 

Copper arsenite, 83. 

Mercury biniodide, 122. 

Quinine hydrochlorate, 147. 
Apoplexy : 

Aconite, 25. 

Arsenic sulphide, 37. 
Appetite, Loss of: 

Cannabis indica, 75. 

Strychnine arseniate, 170. 
Ascaris lumbricoides : 

Calomel, 69. 

Camphor, 71. 
Ascites : 

Arsenic sulphide, 37. 

Calomel, 69. 
Asthenopia : 

Atropine sulphate, 40. 
Asthma . 

Aconite, 25. 

Arsenic sulphide, 37. 

Atropine sulphate, 40. 

Camphor, 71. 

Cannabis indica, 75. 

Copper arsenite, 83. 

Gelsemium, 99. 

Ipecac, 107. 

Mercury biniodide, 122. 

Morphine hydrochlorate, 138. 

Morphine and tartaremetic, 143. 

Nuclein, 187. 

Quinine hydrochlorate, 147. 

Strychnine arseniate, 170. 

Trinitrin, 180. 
Atheroma : 

Arsenic sulphide, 38. 

Quinine hydrochlorate, 147. 
Atrophy, Muscular: 

Copper arsenite, 83. 

Strychnine arseniate, 171. 



Balanitis : 

Calcium sulphide, 58. 
Bed-sores : 

Copper arsenite, 83. 
Biliousness : 

Alterative pill, 33. 

Calomel, 69. 

Copper arsenite, 84. 

Mercury biniodide, 122. 
Bladder, Irritable: 

Atropine sulphate, 40. 

Cannabis indica, 75. 

Strychnine arseniate, 171. 
Blepharitis : 

Calcium sulphide, 58. 

Copper arsenite, 84. 

Iron arseniate, 112. 
Boils : 

Arsenic sulphide, 38. 

Atropine sulphate, 41. 

Calcium sulphide, 58. 

Mercury biniodide, 122. 

Nuclein, 188. 
Bone, Diseases of the : 

Copper arsenite, 84. 

Mercury biniodide, 122. 
Breath, Fetid : 

Camphor, 71. 

Copper arsenite, 84. 
Bright's Disease, see Albu- 
minuria. 
Bronchiectasis: 

Calcium sulphide, 59. 

Quinine hydrochlorate, 147. 
Bronchitis : 

Aconite, 25. 

Alterative pill, 34. 

Atropine sulphate, 41. 

Bryonia, 52. 

Calcium compound, 67. 



THERAPEUTIC INDEX. 



205 



Bronchitis : 

Calcium sulphide, 59. 

Camphor, 72. 

Cannabis indica, 75. 

Ipecac, 107. 

Iron arseniate, 112. 

Morphine hydrochlorate, 138. 

Morphine and tartar emetic, 

143. 

Nuclein, 189. 

Quinine hydrochlorate, 148. 

Strychnine arseniate, 171. 
Bubo : 

Calcium sulphide, 59. 

Gelsemium, 99. 

Mercury biniodide, 123. 
Bunion : 

Mercury biniodide, 123. 
Bursitis : 

Mercury biniodide, 123. 

Cachexia : 

Copper arsenite, 84. 

Iron arseniate, 112. 

Mercury biniodide, 123. 

Rhus toxicodendron, 161. 
Calculi, Biliary : 

Mercury biniodide, 123. 
Calculi, Renal and Vesical : 

Atropine sulphate, 41. 

Bryonia, 52. 
Cancer : 

Iron arseniate, 112. 

Nuclein, 190. 

Zinc sulpho-carbolate, 184. 
Cancrum Oris : 

Copper arsenite, 84. 
Carbuncle : 

Calcium sulphide, 59. 

Iron arseniate, 112. 



Carbuncle : 

Mercury biniodide, 124. 

Quinine hydrochlorate, 148. 
Caries : 

Calcium sulphide, 59. 

Iron arseniate, 112. 
Catarrh, Acute Nasal : 

Acetanilide compound, 17. 

Aconite, 25. 

Alterative pill, 34. 

Atropine sulphate, 41. 

Calcium compound, 68. 

Copper arsenite, 84. 

Gelsemium, 99. 

Morphine and tartar emetic, 

44- 

Quinine hydrochlorate, 148. 
Catarrh, Chronic Nasal : 

Atropine sulphate, 41. 

Copper arsenite, 85. 

Iron arseniate, 112. 

Nuclein, 190. 
Cerebral Anaemia : 

Camphor, 72. 

Gelsemium, 99. 

Ipecac, 108. 

Iron arseniate, 113. 

Mercury biniodide, 124. 

Quinine hydrochlorate, 148. 

Rhus toxicodendron, 161. 

Strychnine arseniate, 171. 

Trinitrin, 181. 
Cerebral Concussion : 

Aconite, 25. 
Cerebral Congestion : 

Aconite, 25. 

Arsenic sulphide, 38. 

Atropine sulphate, 41. 

Bryonia, 52. 

Gelsemium, 100. 



2o6 



THERAPEUTIC INDEX. 



Cerebral Congestion : 

Mercury biniodide, 124. 

Trinitrin, 182. 
Cerebritis : 

Calcium sulphide, 60. 
Chancre : 

Mercury biniodide, 125. 
Chancroid : 

Mercury biniodide, 125. 
Chapped Hands : 

Arsenic sulphide, 38. 
Chest-pains : 

Bryonia, 52. 
Chicken-pox : 

Arsenic sulphide, 38. 

Atropine sulphate, 42. 
Chilblains : 

Mercury biniodide, 125. 
Chlorosis : 

Calcium sulphide, 60. 

Copper arsenite, 85. 

Iron arseniate, 113. 

Mercury biniodide, 125. 

Nuclein, 191. 

Quinine hydrochlorate, 148. 
Choking : 

Atropine sulphate, 42. 
Cholera Asiatic : 

Atropine sulphate, 42. 

Bryonia, 53. 

Calomel, 69. 

Camphor, 72. 

Cannabis indica, 75. 

Copper arsenite, 85. 

Ipecac, 108. 

Mercury biniodide, T25. 

Morphine hydrochlorate, 138. 

Quinine hydrochlorate, 148. 

Strychnine arseniate, 172. 

Zinc sulpho-carbolate, 184. 



Cholera Infantum : 

Calomel, 69. 

Camphor, 72. 

Copper arsenite, 85. 

Nuclein, 191. 

Strychnine arseniate, 172. 

Zinc sulpho-carbolate, 184. 
Cholera Morbus : 

Copper arsenite, 86. 

Morphine hydrochlorate, 138. 
Chordee : 

Aconite, 26. 

Atropine sulphate, 42. 

Camphor, 72. 

Cannabis indica, 76. 

Gelsemium, 100. 

Strychnine arseniate, 172. 
Chorea : 

Atropine sulphate, 42. 

Cannabis indica, 76. 

Copper arsenite, 87. 

Gelsemium, 100. 

Iron arseniate, 114. 

Quinine hydrochlorate, 148. 

Strychnine arseniate, 172. 
Choroiditis : 

Calcium sulphide, 60. 

Gelsemium, 100. 
Cirrhosis : 

Mercury biniodide, 125. 
Climacteric Disorders : 

Aconite, 26. 

Camphor, 72. 

Cannabis indica, 76. 

Iron arseniate, 114. 

Mercury biniodide, 125. 

Strychnine arseniate, 172. 

Trinitrin, 182. 
Colic, Hepatic : 

Atropine sulphate, 42. 



THERAPEUTIC INDEX. 



207 



Colic, Intestinal : 

Alterative pill, 34. 

Atropine sulphate, 42. 

Bryonia, 53. 

Camphor, 72. 

Copper arsenite, 87. 

Morphine hydrochlorate, 139. 

Strychnine arseniate, 172. 
Colic, Lead : 

Atropine sulphate, 42. 

Bryonia, 53. 

Calcium sulphide, 60. 

Copper arsenite, 87. 

Mercury biniodide, 126. 
Coma : 

Trinitrin, 182. 
Conjunctivitis : 

Calcium sulphide, 60. 
Constipation : 

Alterative pill, 34. 

Atropine sulphate, 43. 

Copper arsenite, 87. 

Ipecac, 108. 

Morphine hydrochlorate, 139. 

Strychnine arseniate, 172. 
Convalescence : 

Copper arsenite, 88. 
Convulsions : 

Acetanilide compound, 18. 

Aconite, 26. 

Atropine sulphate, 43. 

Gelsemium, 100. 
Corneal Opacity : 

Calcium sulphide, 60. 

Iron arseniate, 114. 

Mercury biniodide, 126. 
Cough : 

Aconite, 26. 

Alterative pill, 34. 

Atropine sulphate, 43. 



Cough : 

Bryonia, 53. 

Calcium sulphide, 61. 

Calcium compound, 68. 

Cannabis indica, 76. 

Gelsemium, 100. 

Ipecac, 108. 

Trinitrin, 182. 
Croup : 

Aconite, 26. 

Atropine sulphate, 43. 

Calcium sulphide, 61. 

Copper arsenite, 88. 

Ipecac, 108. 

Mercury biniodide, 126. 

Quinine hydrochlorate, 148. 
Cystitis : 

Aconite, 26. 

Bryonia, 53. 

Quinine hydrochlorate, 149. 
Rhus toxicodendron, 161. 

Deafness : 

Calcium sulphide, 61. 

Quinine hydrochlorate, 149. 
Debility : 

Atropine sulphate, 43. 

Cannabis indica, 76. 

Copper arsenite, 88. 

Iron arseniate, 114. 

Mercury biniodide, 126. 

Nuclein, 192. 

Quinine hydrochlorate, 149. 

Strophanthus, 167. 

Strychnine arseniate, 1 72. 
Delirium : 

Atropine sulphate, 43. 

Camphor, 72. 

Cannabis indica, 76. 

Morphine hydrochlorate, 139. 



208 



THERAPEUTIC INDEX. 



Delirium : 

Morphine and tartar emetic, 

145. 
Quinine hydrochlorate, 149. 
Delirium Tremens: 
Atropine sulphate, 43. 
Cannabis indica, 76. 
Copper arsenite, 88. 
Gelsemium, 101. 
Morphine and tartar emetic, 

145. 

Quinine hydrochlorate, 149. 

Strychnine arseniate, 173. 
Dentition : 

Acetanilide compound, 18. 

Atropine sulphate, 43. 

Copper arsenite, 88. 
Diabetes Insipidus : 

Atropine sulphate, 44. 

Mercury biniodide, 126. 

Morphine hydrochlorate, 139. 
Diabetes Mellitus : 

Arsenic sulphide, 39. 

Atropine sulphate, 44. 

Calcium sulphide, 61. 

Iron arseniate, 114. 

Nuclein, 192. 

Quinine hydrochlorate, 150. 
Diarrhoea : 

Aconite, 26. 

Bryonia, 54. 

Calomel, 69. 

Camphor, 72. 

Cannabis indica, 77. 

Copper arsenite, 89. 

Ipecac, 108. 

Mercury biniodide, 126. 

Nuclein, 192. 

Quinine hydrochlorate, 150. 

Zinc sulpho-carbolate, 184. 



Diarrhoea of Phthisis : 

Copper arsenite, 90. 
Diarrhoea of Typhoid : 

Copper arsenite, 90. 
Diphtheria : 

Acetanilide compound, 18. 

Atropine sulphate, 44. 

Copper arsenite, 91. 

Mercury biniodide, 126. 

Nuclein, 193. 

Quinine hydrochlorate, 150. 

Strophanthus, 167. 

Strychnine arseniate, 173. 
Dropsy : 

Aconite, 27. 

Bryonia, 54. 

Cannabis indica, 77. 

Iron arseniate, 1 14. 

Strophanthus, 167. 
Duodenal Catarrh : 

Ipecac, 109. 
Dysentery, see Diarrhoea. 
Dysmenorrhcea : 

Aconite, 27. 

Atropine sulphate, 44. 

Bryonia, 54. 

Calcium sulphide, 61. 

Camphor, 72. 

Cannabis indica, 77. 

Gelsemium, 101. 

Ipecac, 109. 

Iron arseniate, 115. 

Morphine hydrochlorate, 139. 

Nuclein, 194. 

Strychnine arseniate, 173. 
Dyspepsia : 

Atropine sulphate, 44. 

Bryonia, 54. 

Copper arsenite, 91. 

Ipecac, 109. 



THERAPEUTIC INDEX. 



209 



Dyspepsia : 

Mercury biniodide, 126. 

Morphine hydrochlorate, 140. 

Quinine hydrochlorate, 150. 

Strychnine arseniate, 173. 
Dysphagia : 

Atropine sulphate, 45. 
Dysuria : 

Atropine sulphate, 45. 

Camphor, 73. 

Cannabis indica, 77. 

Gelsemium, 101. 

Morphine hydrochlorate, 140. 

Quinine hydrochlorate, 150. 

Strychnine arseniate, 174. 

Earache : 

Calcium sulphide, 62. 

Gelsemium, 101. 

Rhus toxicodendron, 161. 
Ecthyma : 

Mercury biniodide, 127. 

Quinine hydrochlorate, 150. 
Eczema : 

Arsenic sulphide, 39. 

Calcium sulphide, 62. 

Copper arsenite, 91. 

Iron arseniate, 115. 

Mercury biniodide, 127. 

Nuclein, 194. 

Rhus toxicodendron, 162. 
Elephantiasis : 

Iron arseniate, 115. 

Mercury biniodide, 127. 
Emaciation : 

Iron arseniate, 115. 
Emphysema : 

Atropine sulphate, 45. 

Iron arseniate, 115. 

Mercury biniodide, 127. 
14 



Emphysema : 

Strychnine arseniate, 174. 
Empyema : 

Bryonia, 54. 

Calcium sulphide, 62. 

Quinine hydrochlorate, 150. 
Endocarditis : 

Aconite, 27. 

Bryonia, 54. 

Mercury biniodide, 127. 

Quinine hydrochlorate, 151. 
Endometritis : 

Calcium sulphide, 62. 

Quinine hydrochlorate, 151. 
Enteritis : 

Acetanilide compound, 18. 

Aconite, 27. 

Alterative pill, 35. 

Bryonia, 54. 

Calcium sulphide, 62. 

Copper arsenite, 91. 

Gelsemium, 101. 

Iron arseniate, 116. 

Mercury biniodide, 127. 

Morphine hydrochlorate, 140. 
Enuresis : 

Atropine sulphate, 45. 

Rhus toxicodendron, 162. 

Strychnine arseniate, 174. 
Epididymitis, see Testicle, 

Disease of the. 
Epilepsy : 

Atropine sulphate, 45. 

Bryonia, 54. 

Cannabis indica, 77. 

Copper arsenite, 91. 

Iron arseniate, 116. 

Mercury biniodide, 127. 

Quinine hydrochlorate, 151. 

Rhus toxicodendron, 162. 



2IO 



THERAPEUTIC INDEX. 



Epilepsy : 

Strychnine arseniate, 174. 

Trinitrin, 182. 
Epistaxis : 

Aconite, 27. 

Gelsemium, 101. 

Ipecac, 109. 
Erysipelas : 

Aconite, 27. 

Atropine sulphate, 46. 

Iron arseniate, 116. 

Quinine hydrochlorate, 151. 

Rhus toxicodendron, 162. 
Erythema: 

Atropine sulphate, 46. 

Copper arsenite, 92. 

Quinine hydrochlorate, 151. 

Rhus toxicodendron, 162 
Exophthalmus: 

Atropine sulphate, 46. 

Gelsemium, 102. 

Iron arseniate, 116. 

Nuclein, 194. 



Fever : 

Acetanilide compound, 18. 
Aconite, 27. 
Arsenic sulphide, 39. 
Atropine sulphate, 46. 
Calomel, 70. 
Camphor, 73. 
Gelsemium, 102. 
Mercury biniodide, 128. 
Morphine hydrochlorate, 140. 
Nuclein, 195. 

Quinine hydrochlorate, 151. 
Rhus toxicodendron, 162. 
Strophanthus, 167. 
Strychnine arseniate, 174. 



Fissure of the Anus : 

Calomel, 70. 
Flatulence : 

Atropine sulphate, 46. 
Flatulence : 

Camphor, 73. 
Cannabis indica, 77. 
Ipecac, 109. 
Mercury biniodide, 128. 
Strychnine arseniate, 174. 
Zinc sulpho-carbolate, 184. 
Flushing : 
Atropine sulphate, 46. 
Iron arseniate, 116. 
Strychnine arseniate, 174. 



Gastralgia : 

Acetanilide compound, 19. 

Atropine sulphate, 46. 

Bryonia, 55. 

Cannabis indica, 78. 

Copper arsenite, 92. 

Mercury biniodide, 128. 

Morphine hydrochlorate, 140. 

Quinine hydrochlorate, 153. 

Rhus toxicodendron, 163. 

Strychnine arseniate, 174. 

Trinitrin, 182. 
Gastric Ulcer : 

Atropine sulphate, 47. 

Cannabis indica, 78. 

Copper arsenite, 92. 

Mercury biniodide, 128. 

Morphine hydrochlorate, 141. 

Zinc sulpho-carbolate, 184. 
Gastritis : 

Cannabis indica, 78. 

Copper arsenite, 92. 

Ipecac, 109. 



THERAPEUTIC INDEX. 



211 



Gastritis : 

Morphine hydrochlorate, 141. 

Strychnine arseniate, 175. 
Glanders : 

Calcium sulphide, 62. 

Copper arsenite, 92. 

Mercury biniodide, 128. 
Glandular Enlargement : 

Acetanilide compound, 19. 

Atropine sulphate, 47. 

Calcium sulphide, 63. 

Iron arseniate, 117. 

Mercury biniodide, 128. 
Glaucoma : 

Bryonia, 55. 
Gleet : 

Copper arsenite, 92. 

Mercury biniodide, 129. 

Zinc sulpho-carbolate, 184. 
Glossitis : 

Copper arsenite, 93. 
Glottis, CEdema of the : 

Copper arsenite, 93. 
Goitre : 

Mercury biniodide, 129. 
Gonorrhoea : 

Aconite, 29. 

Bryonia, 55. 

Cannabis indica, 78. 

Copper arsenite, 93. 

Gelsemium, 102. 

Mercury biniodide, 129. 

Nuclein, 195. 

Quinine hydrochlorate, 153. 

Zinc sulpho-carbolate, 184. 
Gout: 

Acetanilide compound, 19. 

Atropine sulphate, 47. 

Calcium sulphide, 63. 

Iron arseniate, 117. 



Gout: 

Mercury biniodide, 129. 
Morphine hydrochlorate, 141. 
Quinine hydrochlorate, 153. 
Strychnine arseniate, 175. 
Gums, Spongy: 

Calcium sulphide, 63. 
Copper arsenite, 93. 
Iron arseniate, 117. 

Haematemesis : 

Ipecac, 109. 

Mercury biniodide, 129. 
Haematuria : 

Acetanilide compound, 20. 

Camphor, 73. 

Cannabis indica, 78. 

Quinine hydrochlorate, 153. 
Haemoptysis : 

Acetanilide compound, 20. 

Aconite, 29. 

Atropine sulphate, 47. 

Gelsemium, 102. 

Morphine hydrochlorate, 141. 
Haemorrhage, Intestinal : 

Acetanilide compound, 20. 

Atropine sulphate, 47. 

Morphine hydrochlorate, 141. 
Haemorrhage, Post-partum : 

Ipecac, 109. 

Morphine hydrochlorate, 141. 

Quinine hydrochlorate, 154. 

Strychnine arseniate, 175. 
Haemorrhoids : 

Mercury biniodide, 129. 

Morphine hydrochlorate, 141. 

Rhus toxicodendron, 163. 

Strychnine, arseniate, 175. t 
Hay-fever : 

Atropine sulphate, 47. 



212 



THERAPEUTIC INDEX. 



Hay-fever: 

Bryonia, 55. 

Copper arsenite, 93. 

Quinine hydrochlorate, 153. 
Headache : 

Acetanilide compound, 19. 

Aconite, 29. 

Alterative pill, 35. 

Atropine sulphate, 47. 

Bryonia, 55. 

Camphor, 73. 

Cannabis indica, 78. 

Copper arsenite, 93. 

Gelsemium, 102. 

Iron arseniate, 117. 

Mercury biniodide, 130. 

Morphine hydrochlorate, 142. 

Quinine hydrochlorate, 154. 

Rhus toxicodendron, 163. 

Strychnine arseniate, 175. 

Trinitrin, 182. 
Heartburn : 

Copper arsenite, 94. 

Mercury biniodide, 130. 

Strychnine arseniate, 175. 
Heart, Dilated: 

Cannabis indica, 78. 

Iron arseniate, 117. 

Morphine hydrochlorate, 142. 

Strophanthus, 168. 

Trinitrin, 182. 
Heart, Fatty : 

Atropine sulphate, 47. 

Iron arseniate, 117. 

Rhus toxicodendron, 163. 

Strychnine arseniate, 175. 
Heart, Hypertrophied : 

Acetanilide compound, 19. 

Aconite, 29. 

Atropine sulphate, 47. 



Heart, Hypertrophied : 

Camphor, 73. 

Cannabis indica, 78. 

Gelsemium, 102. 

Trinitrin, 183. 
Heart, Palpitation of the : 

Atropine sulphate, 48. 

Mercury biniodide, 130. 
Heart, Valvular Disease of 
the: 

Aconite, 29. 

Atropine sulphate, 48. 

Iron arseniate, 117. 

Morphine hydrochlorate, 142. 

Strophanthus, 168. 

Strychnine arseniate, 175. 
Hectic : 

Acetanilide compound, 19. 

Gelsemium, 102. 

Iron arseniate, 117. 

Quinine hydrochlorate, 154. 

Strychnine arseniate, 176. 
Hepatitis : 

Acetanilide compound, 20. 

Aconite, 29. 

Bryonia, 55. 

Calomel, 70. 

Mercury biniodide, 130. 

Morphine and tartar emetic, 

145. 
Herpes Zoster : 

Atropine sulphate, 48. 
Rhus toxicodendron, 163. 
Hiccough : 

Atropine sulphate, 48. 
Cannabis indica, 79. 
Morphine hydrochlorate, 142. 
Quinine hydrochlorate, 154. 
Strychnine arseniate, 176. 
Trinitrin, 183. 



THERAPEUTIC INDEX. 



213 



Hydrocephalus : 

Bryonia, 55. 

Mercury biniodide, 130. 
Hydrothorax : 

Bryonia, 55. 
Hypochondriasis : 

Cannabis indica, 79. 

Iron arseniate, 118. 

Strychnine arseniate, 176. 
Hysteria : 

Acetanilide compound, 20. 

Atropine sulphate, 48. 

Camphor, 73. 

Cannabis indica, 79. 

Iron arseniate, 118. 

Morphine and tartar emetic, 

145. 
Strychnine arseniate, 176. 

Impetigo : 

Arsenic sulphide, 39. 
Impotence : 

Cannabis indica, 79. 

Iron arseniate, 118. 

Strychnine arseniate, 176. 
Inflammation : 

Aconite, 30. 

Atropine sulphate, 48. 

Bryonia, 55. 

Calcium sulphide, 63. 

Gelsemium, 102. 

Mercury biniodide, 130. 

Quinine hydrochlorate, 154. 

Rhus toxicodendron, 164. 
Influenza : 

Acetanilide compound, 20. 

Aconite, 30. 

Alterative pill, 35. 

Bryonia, 56. 

Calcium compound, 68. 



Influenza: 

Copper arsenite, 94. 

Gelsemium, 103. 

Morphine and tartar emetic, 145 

Nuclein, 195. 

Quinine hydrochlorate, 154. 

Rhus toxicodendron, 164. 
Insomnia : 

Acetanilide compound, 20. 

Aconite, 30. 

Atropine sulphate, 48. 

Camphor, 73. 

Cannabis indica, 79. 

Gelsemium, 103. 

Morphine and tartar emetic, 
145. 

Morphine hydrochlorate, 142. 

Nuclein, 196. 
Intermittent Fever : 

Acetanilide compound, 20. 

Aconite; 30. 

Gelsemium, 103. 

Ipecac, no. 

Iron arseniate, 118. 

Mercury biniodide, 1 30. 

Quinine hydrochlorate, 154. 

Strychnine arseniate, 176. 
Intertrigo : 

Copper arsenite, 94. 

Mercury biniodide, 131. 
Iritis : 

Atropine sulphate, 49. 

Calcium sulphide, 63. 

Mercury biniodide, 131. 
Irritability : 

Bryonia, 56. 

Jaundice : 
Calomel, 70. 
Ipecac, no. 



214 



THERAPEUTIC INDEX. 



Jaundice : 

Mercury biniodide, 131. 
Quinine hydrochlorate, 156. 

Lactation : 

Atropine sulphate, 49. 
Laryngismus Stridulus : 

Acetanilide compound, 21. 

Atropine sulphate, 49. 

Strychnine arseniate, 176. 
Laryngitis : 

Aconite, 30. 

Atropine sulphate, 49. 

Calcium sulphide, 63. 
Leucorrhcea : 

Calcium sulphide, 63. 

Copper arsenite, 94. 

Iron arseniate, 118. 
Lichen : 

Calcium sulphide, 63. 

Iron arseniate, 118. 
Locomotor Ataxia : 

Acetanilide compound, 21. 

Cannabis indica, 79. 

Rhus toxicodendron, 164. 
Lumbago : 

Acetanilide compound, 21. 

Atropine sulphate, 49. 

Bryonia, 56. 

Cannabis indica, 79. 

Quinine hydrochlorate, 156. 

Rhus toxicodendron, 164. 
Lupus : 

Iron arseniate- 118. 

Malaria : 

Nuclein, 196. 
Mania : 

Acetanilide compound, 21. 
Atropine sulphate, 49. 
Gelsemium, 103. 



Mania :„ 

Iron arseniate, 118. 
Morphine and tartar emetic, 

145. 
Mastitis : 

Atropine sulphate, 49. 

Calcium sulphide, 63. 

Rhus toxicodendron, 164. 
Measles: 

Acetanilide compound, 21. 

Aconite, 30. 

Camphor, 73. 

Gelsemium, 103. 

Nuclein, 197. 

Quinine hydrochlorate, 156. 
Melancholia : 

Atropine sulphate, 49. 

Cannabis indica, 79. 

Gelsemium, 103. 

Iron arseniate, 118. 

Strychnine arseniate, 176. 
Melanosis : 

Nuclein, 197. 
Meniere's Disease : 

Gelsemium, 103. 

Quinine hydrochlorate, 156. 
Meningitis, Cerebral and Cere- 
brospinal : 

Acetanilide compound, 21. 

Aconite, 30. 

Bryonia, 56. 

Gelsemium, 104. 

Mercury biniodide, 13 1. 

Morphine hydrochlorate, 142. 

Quinine hydrochlorate, 156. 
Menorrhagia : 

Cannabis indica, 79. 

Iron arseniate, 118. 

Mercury biniodide, 131. 

Quinine hydrochlorate, 156. 



THERAPEUTIC INDEX. 



215 



Metritis : 

Aconite, 30. 

Gelsemium, 104. 
Muscae Volitantes : 

Iron arseniate, 119. 

Mercury biniodide, 131. 
Myalgia : 

Bryonia, 56. 

Gelsemium, 104. 

Rhus toxicodendron, 164. 
Myelitis : 

Atropine sulphate, 50. 

Mercury biniodide, 131. 

Strychnine arseniate, 176. 

Nausea : 

Copper arsenite, 94. 

Mercury biniodide, 132. 

Morphine hydrochlorate, 142. 
Nephritis, see also Albuminu- 
ria : 

Aconite, 30. 

Atropine sulphate, 50. 

Camphor, 74. 

Cannabis indica, 80. 

Trinitrin, 183. 
Nervousness : 

Acetanilide compound, 21. 

Aconite, 31. 

Alterative pill, 35. 

Gelsemium, 104. 

Iron arseniate, 119. 

Strychnine arseniate, 177. 
Neuralgia : 

Acetanilide compound, 21. 

Aconite, 31. 

Atropine sulphate, 50. 

Cannabis indica, 80. 

Gelsemium, 104. 

Iron arseniate, 119. 



Neuralgia : 

Mercury biniodide, 132. 

Quinine hydrochlorate, 156. 

Rhus toxicodendron, 164. 

Strychnine arseniate, 177. 

Trinitrin, 183. 
Neurasthenia : 

Nuclein, 197. 
Nightmare : 

Copper arsenite, 94. 
Night Sweats : 

Nuclein, 197. 
Nipples, Sore : 

Copper arsenite, 94. 
Nodes : 

Mercury biniodide, 132. 
Nyctalopia : 

Quinine hydrochlorate, 156. 

Strychnine arseniate, 177. 
Nymphomania : 

Camphor, 74. 

Ipecac, no. # 

Obesity : 

Arsenic sulphide, 39. 
Onychia, see Paronychia. 
Ophthalmia, see Conjunctivi- 
tis. 
Orchitis, see Testicle, Disease 

of the. 
Otitis, see Earache. 
Otorrhcea : 

Calcium sulphide, 64. 

Mercury biniodide, 132. 
Ovaritis and Neuralgia : 

Calcium sulphide, 64. 
Ozasna : 

Calcium sulphide, 64. 

Iron arseniate, 119. 

Mercury biniodide, 132. 



2l6 



THERAPEUTIC INDEX. 



Paronychia : 

Calcium sulphide, 64. 

Gelsemium, 104. 

Mercury biniodide, 132. 
Parotiditis : 

Acetanilide compound, 22. 

Aconite, 31. 

Mercury biniodide, 132. 
Pemphigus : 

Arsenic sulphide, 39. 

Calcium sulphide, 64. 

Iron arseniate, 119. 
Pericarditis : 

Acetanilide compound, 22. 

Aconite, 31. 

Bryonia, 56. 

Quinine hydrochlorate, 157. 

Strophanthus, 168. 
Periostitis : 

Mercury biniodide, 132. 
Peritonitis : 

^etanilide compound, 22. 

Aconite, 31. 

Bryonia, 56. 

Copper arsenite, 94. 

Mercury biniodide, 133. 

Quinine hydrochlorate, 157. 
Perspiration : 

Alterative pill, 35. 

Atropine sulphate, 50. 

Iron arseniate, 119. 

Quinine hydrochlorate, 157. 

Strychnine arseniate, 177. 
Pertussis : 

Aconite, 31. 

Calcium compound, 68. 

Calcium sulphide, 64. 

Gelsemium, 104. 

Ipecac, no. 

Quinine hydrochlorate, 157. 



Pharyngitis : 

Aconite, 31. 

Atropine sulphate, 50. 

Calcium sulphide, 64. 

Ipecac, no. 

Iron arseniate, 119. 

ISuclein, 197. 

Quinine hydrochlorate, 157. 

Rhus toxicodendron, 164. 

Strychnine arseniate, 177. 
Phlebitis : 

Mercury biniodide, 133. 
Phlegmasia Alba Dolens : 

Mercury biniodide, 133. 
Photophobia: 

Atropine sulphate, 50. 
Phthisis : 

Acetanilide compound, 22. 

Alterative pill, 35. 

Atropine sulphate, 50. 

Bryonia, 56. 

Calcium compound, 68. 

Calcium sulphide, 64. 

Camphor, 74. 

Cannabis indica, 80. 

Copper arsenite, 94. 

Gelsemium, 104. 

Ipecac, no. 

Iron arseniate, 119. 

Quinine hydrochlorate, 157. 

Strophanthus, 168. 

Strychnine, arseniate, 177. 

Trinitrin, 183. 
Pityriasis : 

Arsenic sulphide, 39. 

Iron arseniate, 119. 
Pleurisy : 

Acetanilide compound, 22. 

Aconite, 31. 

Bryonia, 56. 



THERAPEUTIC INDEX. 



217 



Pleurisy : 

Gelsemium, 105. 

Mercury biniodide, 133. 

Morphine hydrochlorate, 143. 

Quinine hydrochlorate, 157. 
Pleurodynia : 

Acetanilide compound, 22. 

Iron arseniate, 119. 

Quinine hydrochlorate, 158. 

Rhus toxicodendron, 164. 
Pleuropneumonia : 

Bryonia, 57. 
Pneumonia : 

Acetanilide compound, 22. 

Aconite, 31. 

Alterative pill, 35. 

Bryonia, 57. 

Calcium sulphide, 65. 

Gelsemium, 105. 

Mercury biniodide, 133. 

Morphine and tartar emetic, 
146. 

Nuclein, 189. 

Quinine hydrochlorate, 158. 

Strophanthus, 168. 

Strychnine arseniate, 177. 
Prolapsus Ani : 

Copper arsenite, 95. 

Mercury biniodide, 133. 

Strychnine arseniate, 177. 
Prolapsus Uteri : 

Strychnine arseniate, 177. 
Prostate, Enlarged : 

Mercury biniodide, 133. 
Prostatitis : 

Calcium sulphide, 65. 
Prurigo and Pruritus : 

Arsenic sulphide, 39. 

Calcium sulphide, 65. 

Mercury biniodide, 133. 



Psoriasis : 

Arsenic sulphide, 39. 

Calcium sulphide, 65. 

Iron arseniate, 120. 

Mercury biniodide, 133. 
Ptosis : 

Strychnine arseniate, 178. 
Ptyalism : 

Atropine sulphate, 50. 

Calcium sulphide, 65. 
Puerperal Convulsions : 

Aconite, 31. 

Camphor, 74. 
Puerperal Fever : 

Aconite, 32. 

Copper arsenite, 95. 

Mercury biniodide, 134. 

Quinine hydrochlorate, 158. 

Strychnine arseniate, 178. 
Puerperal Mania : 

Camphor, 74, 

Cannabis indica, 80. 

Iron arseniate, 120. 

Morphine and tartar emetic, 
146. 

Quinine hydrochlorate, 158. 
Puerperal Peritonitis : 

Aconite, 32. 
Purpura : 

Arsenic sulphide, 40. 

Iron arseniate, 120. 

Quinine hydrochlorate, 158. 

Rhus toxicodendron, 165. 

Strychnine arseniate, 178. 
Pyaemia : 

Quinine hydrochlorate, 158. 
Pyelo-nephritis : 

Calcium sulphide, 65. 
Pyrosis : 

Camphor, 74. 



218 



THERAPEUTIC INDEX. 



Pyrosis : 

Copper arsenite, 95. 
Mercury biniodide, 134. 
Quinine hydrochlorate, 158. 
Strychnine arseniate, 178. 

Relapsing Fever, see Inter- 
mittent Fever. 
Renal Calculi, see Calculi. 
Rheumatism, Acute: 

Acetanilide compound, 22. 

Aconite, 32. 

Bryonia, 57. 

Mercury biniodide, 134. 

Quinine hydrochlorate, 158. 

Rhus toxicodendron, 165. 
Rheumatism, Chronic : 

Bryonia, 57. 

Quinine hydrochlorate, 159. 

Rhus toxicodendron, 165. 
Rheumatoid Arthritis : 

Acetanilide compound, 22. 

Calcium sulphide, 65. 

Iron arseniate, 120. 

Mercury biniodide, 134. 

Nuclein, 187. 

Quinine hydrochlorate, 159. 

Rhus toxicodendron, 165. 
Rickets : 

Iron arseniate, 120. 

Scabies : 

Calcium sulphide, 65. 
Scarlet Fever: 

Acetanilide compound, 23. 
Aconite, 32. 
Atropine sulphate, 50. 
Copper arsenite, 95. 
Gelsemium, 105. 
Iron arseniate, 120. 
Mercury biniodide, 134. 



Scarlet Fever : 

Nuclein, 198. 

Quinine hydrochlorate, 159. 

Rhus toxicodendron, 165. 

Strychnine arseniate, 178. 
Sciatica : 

Acetanilide compound, 23. 

Mercury biniodide, 134. 

Morphine hydrochlorate, 143. 

Nuclein, 198. 

Rhus toxicodendron, 166. 

Strychnine arseniate, 178. 
Scrofula : 

Calcium sulphide, 65. 

Iron arseniate, 120. 

Mercury biniodide, 134. 
Scurvy : 

Atropine sulphate, 50. 

Copper arsenite, 95. 

Iron arseniate, 120. 

Quinine hydrochlorate, 159. 
Seasickness : 

Acetanilide compound, 23. 

Cannabis indica, 80. 

Copper arsenite, 95. 

Strychnine arseniate, 178. 
Seborrhcea : 

Calcium sulphide, 65. 
Sexual Excitement : 

Acetanilide compound, 23. 

Camphor, 74. 
Sleeplessness : 

Cannabis indica, 80. 

Gelsemium, 105. 

Strychnine arseniate, 178. 
Sneezing : 

Copper arsenite, 95. 

Gelsemium, 105. 
Spermatorrhoea : 

Atropine sulphate, 50. 



THERAPEUTIC INDEX. 



219 



Spermatorrhoea : 

Camphor, 74. 

Iron arseniate, 120. 

Quinine hydrochlorate, 159. 

Strychnine arseniate, 178. 
Spinal Congestion : 

Acetanilide compound, 23. 

Gelsemium, 105. 
Spinal Paralysis and Soften- 
ing : 

Mercury biniodide, 134. 
Splenic Affections : 

Mercury biniodide, 134. 

Quinine hydrochlorate, 159. 
Sprains : 

Rhus toxicodendron, 166. 
Sterility : 

Calcium sulphide, 66, 
Stomatitis : 

Copper arsenite, 96. 

Mercury biniodide, 135. 
Strabismus : 

Atropine sulphate, 51. 

Mercury biniodide, 135. 
Strophulus : 

Copper arsenite, 96. 

Mercury biniodide, 135. 
Sunstroke : 

Acetanilide compound, 23. 

Gelsemium, 105. 

Quinine hydrochlorate, 159. 

Strychnine arseniate, 178. 

Trinitrin, 183. 
Suppuration : 

Calcium sulphide, 66. 

Mercury biniodide, 135. 

Quinine, hydrochlorate, 159. 
Syncope : 

Atropine sulphate, 51. 

Camphor, 75. 



Syncope : 

Strychnine arseniate, 178. 

Trinitrin, 183. 
Synovitis : 

Bryonia, 57. 

Calcium sulphide, 66. 

Mercury biniodide, 135. 
Syphilis : 

Calcium sulphide, 66. 

Calomel, 70. 

Copper arsenite, 96. 

Mercury biniodide, 135. 

Tabes Mesenterica : 

Iron arseniate, 121. 
Testicle, Diseases of the : 

Acetanilide compound, 23. 

Aconite, 32. 

Atropine sulphate, 51. 

Mercury biniodide, 135. 
Tetanus : 

Cannabis indica, 80. 

Gelsemium, 105. 

Quinine hydrochlorate, 160. 

Strychnine arseniate, 179. 
Thread-worm : 

Calomel, 71. 
Tic-douloureux : 

Acetanilide compound, 23. 

Aconite, 32. 

Cannabis indica, 80. 

Gelsemium, 106. 

Iron arseniate, 121. 
Tinea Favosa : 

Calcium sulphide, 66. 

Mercury biniodide, 136. 
Tongue, Disease of the, see 

Glossitis. 
Tonsillitis : 

Aconite, 32. 



220 



THERAPEUTIC INDEX. 



Tonsillitis : 

Atropine sulphate, 51. 

Calcium sulphide, 66. 

Copper arsenite, 96. 

Gelsemium, 106. 

Mercury biniodide, 136. 

Nuclein, 198. 

Quinine hydrochlorate, 160. 

Rhus toxicodendron, 166. 
Toothache : 

Acetanilide compound, 24. 

Calcium sulphide, 66. 

Gelsemium, 106. 

Quinine hydrochlorate, 160. 
Trismus : 

Aconite, 33. 

Cannabis indica, 80. 

Gelsemium, 106. 

Mercury biniodide, 136. 
Tuberculosis : 

Nuclein, 199. 
Tympanites : 

Bryonia, 57. 

Copper arsenite, 96. 
Typhlitis : 

Calcium sulphide, 66. 
Typhoid Fever : 

Acetanilide compound, 24. 

Aconite, 33. 

Atropine sulphate, 51. 

Bryonia, 57. 

Calcium sulphide, 67. 

Calomel, 71. 



Typhoid Fever: 

Cannabis indica, 81. 
Copper arsenite, 96. 
Gelsemium, 106. 
Mercury biniodide, 136. 
Morphine and tartar emetic, 

146. 
Nuclein, 201. 

Quinine hydrochlorate, 160. 
Rhus toxicodendron, 166. 
Strophanthus, 168. 
Strychnine arseniate, 179. 
Zinc sulpho-carbolate, 185. 
Typhus Fever : 
Aconite, 33. 
Atropine sulphate, 51. 
Camphor, 75. 

Quinine hydrochlorate, 160. 
Strychnine arseniate, 179. 

Vomiting : 

Copper arsenite, 97. 
Mercury biniodide, 137. 
Strychnine arseniate, 179. 

Whooping-cough, see Pertus- 



Yellow Fever : 

Camphor, 75. 
Copper arsenite, 98. 
Gelsemium, 106. 
Strychnine arseniate, 179. 
Zinc sulpho-carbolate, 185. 



THE END. 



THE DISEASES OF 
INFANCY AND CHILDHOOD. 

For the Use of Students and Practitioners of Medicine. 
By L. EMMETT HOLT, A. M., M. D., 

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